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Digestive HealthDigestive Health

Digestive medicines are chosen according to the cause of symptoms, not the symptom alone. Persistent reflux, nausea, abdominal pain or bowel changes may need assessment before treatment.

Motilium

Domperidone

10mg

Domperidone 10mg film-coated tablets, used in the management of nausea and vomiting. A peripheral dopamine antagonist that speeds gut transit.

From$0.46/ tabletView

Zofran

Ondansetron

4 · 8mg

Ondansetron 4mg and 8mg, as film-coated and orodispersible tablets, used for nausea and vomiting including after surgery. A 5-HT3 antagonist.

From$1.17/ tabletView

Maxolon

Metoclopramide

10mg

Metoclopramide 10mg tablets, used in the management of nausea, vomiting and gastroparesis. A dopamine antagonist that speeds gastric emptying.

From$0.57/ tabletView

Reglan

Metoclopramide

10mg

A 10mg metoclopramide tablet for nausea, vomiting and gastroparesis, blocking dopamine at the chemoreceptor trigger zone while moving the gut along.

From$0.43/ tabletView

Asacol

Mesalazine

400mg

Mesalazine 400mg gastro-resistant tablets, used for ulcerative colitis. An aminosalicylate that acts locally on the lining of the intestine.

From$1.24/ tabletView

Cytotec

Misoprostol

100 · 200mcg

Misoprostol 100mcg and 200mcg tablets, used for gastric and duodenal ulcer, ulcer prophylaxis and medical termination of pregnancy. A prostaglandin E1 analogue.

From$0.91/ tabletView

Urso

Ursodeoxycholic Acid

150 · 300mg

Ursodeoxycholic acid 150mg and 300mg tablets, used in the management of primary biliary cholangitis and dissolution of gallstones. A natural bile acid.

From$1.07/ tabletView

Azulfidine

Sulfasalazine

500mg

Sulfasalazine 500mg tablets, used in the management of rheumatoid arthritis, ulcerative colitis and Crohn's disease. A sulfonamide DMARD.

From$0.85/ tabletView

Pentasa

Mesalazine

400mg

Mesalazine as a 400mg prolonged-release tablet, used in the management of ulcerative colitis and Crohn's disease. The release is spread along the gut.

From$1.32/ tabletView

Serc

Betahistine

8 · 16 · 24mg

Betahistine 8mg, 16mg and 24mg tablets, used for Meniere's disease, vertigo, tinnitus and hearing loss. A histamine analogue acting in the inner ear.

From$1.19/ tabletView

Dexilant

Dexlansoprazole

30 · 60mg

Dexlansoprazole 30mg and 60mg modified-release capsules, used for reflux disease and erosive oesophagitis. A proton pump inhibitor of the H+/K+-ATPase.

From$0.94/ tabletView

Creon

Pancrelipase

150mg

Pancrelipase 150mg gastro-resistant capsules, used for exocrine pancreatic insufficiency. Lipases, proteases and amylases supplementing what the pancreas lacks.

From$3.75/ tabletView

Prevacid

Lansoprazole

15 · 30mg

Lansoprazole 15mg and 30mg hard capsules, used for reflux disease and peptic ulcer disease. A benzimidazole proton pump inhibitor.

From$0.49/ tabletView

Aciphex

Rabeprazole

10 · 20mg

Rabeprazole gastro-resistant tablets at 10mg and 20mg, used for reflux disease and duodenal ulcer. A proton pump inhibitor that cuts stomach acid output.

From$0.54/ tabletView

Compazine

Prochlorperazine

5mg

Compazine is prochlorperazine 5mg tablets for nausea, vomiting and vertigo. A phenothiazine that blocks dopamine at the chemoreceptor trigger zone.

From$0.46/ tabletView

Actigall

Ursodeoxycholic Acid

300mg

Ursodeoxycholic acid 300mg capsules, used in the management of biliary cirrhosis and gallstones. A bile acid that lowers cholesterol output from the liver.

From$2.44/ tabletView

Ranitidine Tablets

Ranitidine

150 · 300mg

Ranitidine 150mg and 300mg tablets, used for peptic ulcer disease and reflux disease. An H2-receptor antagonist that cuts stomach acid.

From$0.21/ tabletView

Motegrity

Prucalopride

2mg

Prucalopride 2mg film-coated tablets, used in the management of chronic constipation. A 5-HT4 agonist that stimulates colonic motility.

From$1.56/ tabletView

Key points

  • Acid reducers, anti-nausea medicines and anti-inflammatory bowel medicines address different problems and are not interchangeable.
  • Persistent or recurring symptoms need review because infection, inflammation, bleeding and medicine effects can look similar.
  • Vomiting blood, black stools, severe abdominal pain or inability to keep fluids down require urgent care.

The listings are for comparison; suitability and supply depend on clinician and pharmacy checks, stock, destination rules and any prescription requirements.

How the medicine groups differ

  • Acid-reducing medicines: lansoprazole and rabeprazole reduce stomach acid but do not identify or remove every cause of reflux or ulcer symptoms.
  • Anti-nausea medicines: metoclopramide and domperidone have different movement, heart-rhythm and interaction considerations.
  • Bowel and bile medicines: mesalazine is used for specific inflammatory bowel conditions, while ursodeoxycholic acid is used for selected bile-related conditions.

What these medicines are used for

Linked conditions include gastro-oesophageal reflux disease, peptic ulcer disease, ulcerative colitis and nausea. These are separate problems that happen to share the digestive tract. Acid suppression helps the first two, inflammatory bowel disease needs medicines aimed at the immune response, and nausea is a symptom with many causes rather than a diagnosis.

Important safety checks

Pregnancy, heart-rhythm problems, kidney or liver disease and other medicines can change suitability. Long-term acid suppression and repeated use of anti-nausea medicine should be reviewed rather than continued without reassessment.

When to seek urgent care

Seek urgent help for vomiting blood, black or bloody stools, severe or worsening abdominal pain, a rigid or swollen abdomen, fainting, severe dehydration or difficulty swallowing with food getting stuck.

Further reading