Skip to content

Domperidone

Domperidone is a dopamine antagonist that can increase upper digestive-tract movement and reduce Nausea and Vomiting. Its use is limited by heart-rhythm risk and important interactions.

Motilium

Nausea, Vomiting

10mg

Domperidone 10mg film-coated tablets, used in the management of nausea and vomiting. A peripheral dopamine antagonist that speeds gut transit.

From$0.46/ tabletView

Key points

  • Domperidone treats symptoms rather than the underlying cause of persistent nausea or vomiting.
  • Heart disease, abnormal electrolytes and medicines that prolong the QT interval or raise domperidone levels can increase arrhythmia risk.
  • Fainting, chest pain or a fast or irregular heartbeat requires urgent medical care.

Select a listed product and pack to order online. Product information is not a recommendation. Whether it suits you depends on the cause of symptoms; ask your doctor or pharmacist.

What domperidone is used for

Domperidone may be used for selected nausea and vomiting or motility-related symptoms. Ongoing vomiting, weight loss, swallowing difficulty or gastrointestinal bleeding needs diagnosis rather than repeated symptom suppression.

Important safety checks

Heart-rhythm history, age, liver function and potassium or magnesium disturbances can affect suitability. Several antibiotics, antifungals, heart medicines and other products can increase cardiac risk. The lowest suitable exposure and shortest necessary treatment are clinical decisions; do not extend treatment without review.

When to seek urgent care

Seek emergency help for fainting, chest pain, severe breathlessness or a rapid or irregular heartbeat. Vomiting blood, black stools, severe abdominal pain, marked dehydration, confusion or inability to keep fluids down also requires urgent assessment.

Further reading

What is domperidone used for?

Domperidone is used for some types of nausea and vomiting and for symptoms linked to slow digestion. It eases the symptoms rather than treating the cause, so ongoing vomiting needs to be checked by a doctor.

How does domperidone work?

Domperidone speeds up the movement of food through the upper gut and blocks dopamine signals that trigger nausea. This helps settle feelings of sickness.

What domperidone product does SGMeds list?

The domperidone product on SGMeds is Motilium, and its page gives the strengths and pack sizes.

How long does domperidone take to work?

Domperidone usually starts to work within 30 to 60 minutes, and the effect lasts about 4 to 8 hours.

What are the side effects of domperidone?

Dry mouth is common, and some people get headaches, diarrhoea or anxiety. Rarely it can cause a serious heart rhythm problem or sudden cardiac death, which needs immediate medical attention.

Can domperidone be taken with other medicines?

Antacids and medicines that prolong the QT interval can interact with it. Some antibiotics, antifungals and heart medicines can also raise the risk of heart rhythm problems, so check with a doctor or pharmacist before combining them.

Who should not take domperidone?

It is not suitable if you have severe liver problems or a heart conduction disorder. If you have a heart condition, low or high electrolyte levels, or reduced liver function, ask a doctor or pharmacist first.

How is domperidone priced?

The product on this page shows a price for each strength and pack size in Singapore dollars, converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.

Payment and prices →

Can I order domperidone without a prescription?

Yes. SGMeds does not ask for a prescription to order domperidone: we place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.

Ordering without a prescription →

Where can I buy domperidone in Singapore?

You can order domperidone here on SGMeds: choose the product, strength and pack, then check out. We deliver to Singapore and Malaysia. Express shipping is tracked and takes up to 1 week, and Regular shipping takes up to 3 weeks.

How ordering works →