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Bladder HealthBladder Health

Medicines for overactive bladder can reduce urgency, frequency and leakage. Similar symptoms can result from infection, urinary retention, stones, diabetes or neurological conditions, so assessment matters before treatment.

Vesicare

Solifenacin

5 · 10mg

Solifenacin 5mg and 10mg film-coated tablets, used in the management of overactive bladder. A competitive muscarinic receptor antagonist.

From$1.86/ tabletView

Myrbetriq

Mirabegron

50mg

Myrbetriq is mirabegron 50mg in a prolonged-release tablet for overactive bladder, a beta-3 agonist rather than an antimuscarinic.

From$2.99/ tabletView

Ditropan

Oxybutynin

2.5 · 5mg

Oxybutynin 2.5mg and 5mg tablets, used in the management of urinary incontinence and detrusor overactivity. An antispasmodic acting on bladder muscle.

From$0.70/ tabletView

Detrol

Tolterodine

1 · 2mg

Tolterodine 1mg and 2mg, as film-coated tablets and prolonged-release capsules, used in the management of overactive bladder. An antimuscarinic.

From$1.50/ tabletView

Urispas

Flavoxate

200mg

Flavoxate 200mg film-coated tablets, used for urinary frequency and urgency. A direct smooth muscle relaxant acting in the bladder wall.

From$1.19/ tabletView

Elmiron

Pentosan Polysulfate

100mg

Pentosan polysulfate 100mg hard capsules, used in the management of interstitial cystitis. A heparin-like compound that coats the bladder lining.

From$4.25/ tabletView

Nocdurna

Desmopressin

0.2mg

Desmopressin 0.2mg orodispersible tablets placed under the tongue, used in the management of nocturia and nocturnal enuresis. A vasopressin analogue.

From$4.16/ tabletView

Oxytrol

Oxybutynin

5mg

Oxybutynin 5mg as a transdermal patch, used in the management of overactive bladder. An anticholinergic delivered through the skin rather than swallowed.

From$1.10/ tabletView

Detrol LA

Tolterodine

4mg

Detrol LA is tolterodine 4mg in a prolonged-release hard capsule for overactive bladder. A competitive muscarinic antagonist taken once a day.

From$2.58/ tabletView

Enablex

Darifenacin

7.5mg

Darifenacin 7.5mg prolonged-release tablets, used in the management of overactive bladder. A selective M3 muscarinic antagonist taken once daily.

From$2.55/ tabletView

Urecholine

Bethanechol

25mg

Bethanechol 25mg tablets, used in the management of urinary retention. A muscarinic agonist that mimics acetylcholine to contract the bladder.

From$1.36/ tabletView

Key points

  • Antimuscarinics and other bladder medicines differ in effects on the bowel, eyes, cognition, blood pressure and ability to empty the bladder.
  • Bladder training, fluid timing and management of contributing conditions may be used alongside medicine.
  • Blood in urine, fever with flank pain or inability to pass urine requires prompt medical care rather than symptom treatment.

Listings are for comparison and general information, not a diagnosis or recommendation; suitability and supply depend on clinician and pharmacy checks and prescription requirements.

How the medicine groups differ

Antimuscarinics such as tolterodine, oxybutynin and solifenacin reduce involuntary bladder contractions but may cause dry mouth, constipation, blurred vision or cognitive effects. Mirabegron works through a different pathway and can affect blood pressure. Flavoxate has a separate role that depends on the diagnosis and local clinical practice.

What these medicines are used for

This category includes medicines used for overactive bladder, urinary urgency and urinary incontinence. They do not treat every cause of urinary frequency or leakage.

Important safety checks

A clinician may check urine, bladder emptying, blood pressure and current medicines. Glaucoma, severe constipation, urinary retention, kidney or liver problems and cognitive impairment can change the choice. Report difficulty passing urine after starting treatment.

When to seek urgent care

Seek urgent assessment for inability to urinate, blood or clots in urine, severe lower abdominal pain, fever with back or flank pain, vomiting, new leg weakness or numbness around the groin. New loss of bladder control with neurological symptoms is an emergency.

Further reading