Zofran
Ondansetron 4mg and 8mg, as film-coated and orodispersible tablets, used for nausea and vomiting including after surgery. A 5-HT3 antagonist.
- Category
- Digestive Health
- Active ingredient
- Ondansetron
- Route
- Oral use
- Form
- Film-coated tablet; Orodispersible tablet
- Strengths
- 4 · 8mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Zofran on your behalf.
- Condition
- Nausea and Vomiting
- Therapeutic class
- Antiemetic; 5-HT3 Antagonist
- Pharmacological class
- 5-HT3 Receptor Antagonist
- Known off-label uses
- gastroenteritis
- Contraindications
- hypersensitivity to ondansetron; concurrent use of apomorphine
- Minor side effects
- headache; flushing; constipation
- Moderate side effects
- elevation of liver enzymes; dizziness; abdominal discomfort
- Dosage forms
- Film-coated tablet; Orodispersible tablet
- Administration route
- Oral use
- Originator
- Novartis
- Onset Time
- 30–60 minutes
- Duration
- 8–12 hours
- Storage instructions
- Store in a cool, dry place away from direct light and humidity.
- Drug interactions
- apomorphine; qt interval prolonging drugs
- Age restrictions
- Use with caution in children; follow specialist paediatric dosing guidance.
Precautions and warnings
monitor for QT prolongation; use caution in patients with hepatic impairment; monitor for severe constipation; may mask symptoms of bowel obstruction
Serious side effects
qt prolongation, requires immediate medical attention; arrhythmia, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Ondansetron 4mg and 8mg, as film-coated and orodispersible tablets, used for nausea and vomiting including after surgery. A 5-HT3 antagonist.
Mechanism of action
Ondansetron functions as a potent, highly selective 5-HT3 receptor antagonist. By blocking these receptors located on the vagus nerve terminals and in the chemoreceptor trigger zone of the brain, it effectively inhibits the emetogenic response to chemotherapy and surgery.
Pregnancy and breastfeeding
Pregnancy: Use of ondansetron is not routinely recommended, especially during the first trimester. Breastfeeding: Formula feeding is recommended if treatment is necessary.
Zofran contains ondansetron, a medication used to prevent nausea and vomiting, including post-operative nausea and vomiting. It is supplied as a tablet in strengths of 4mg and 8mg. This treatment is widely used for managing symptoms related to surgical recovery or medical therapies.
Buying Zofran online
Generic ondansetron, much of it made in India, provides a more affordable option than the original brand for expats or residents lacking easy access to a well stocked pharmacy.
Do I get the original Zofran?
No. SGMeds ships a generic with the same active ingredient (ondansetron) at the strength you choose, not the original Zofran made by Novartis. We use the brand name so you can find the medicine, and the generic's manufacturer varies with stock.
How much does Zofran cost in Singapore?
Zofran comes in 4 and 8mg strengths, in packs of 30 to 180 tablets. Each option's price is shown on this page in Singapore dollars, converted from US dollars, so the exchange rate can change the final amount. Larger packs work out cheaper per tablet.
Payment and prices →What is Zofran used for?
Zofran is used for nausea and vomiting.
What are the side effects of Zofran?
The most common side effects of ondansetron are headache, flushing and constipation. Less common ones are elevation of liver enzymes, dizziness and abdominal discomfort. Serious side effects include a heart rhythm change (QT prolongation), arrhythmia and a severe allergic reaction (anaphylaxis). Get medical help straight away if you notice one of these serious effects.
What does Zofran interact with?
Ondansetron can interact with apomorphine and drugs that prolong the QT interval. Before you start Zofran, tell your doctor or pharmacist about any medicines, supplements or herbal remedies you take.
How fast does Zofran work?
Zofran usually starts to work within 30 to 60 minutes. This varies from person to person.
Can I order Zofran without a prescription?
Yes. SGMeds does not ask for a prescription to order Zofran: we place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.
Ordering without a prescription →Where can I buy Zofran in Singapore?
You can order Zofran here on SGMeds: choose the strength and pack, then check out. Parcels go to Singapore and Malaysia by Express shipping (tracked, up to 1 week) or Regular shipping (up to 3 weeks).
How ordering works →What you will receive
Zofran is the originator brand name, made by Novartis. We use it here to identify the medicine only; we are not affiliated with Novartis and do not ship the original Zofran.
- You receive a generic equivalent: the same active ingredient (Ondansetron) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.