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Epilepsy

Epilepsy is a neurological disorder characterised by an enduring tendency to have unprovoked seizures, rather than every isolated seizure event.

Neurontin

Gabapentin

100 · 300 · 400 · 600mg

Gabapentin hard capsules from 100mg to 600mg, used in the management of epilepsy and neuropathic pain. A structural analogue of GABA.

From$0.43/ tabletView

Lamictal

Lamotrigine

25 · 50 · 100 · 200mg

Lamotrigine 25mg to 200mg, as plain and dispersible tablets, used in the management of epilepsy and bipolar disorder. It blocks voltage-gated sodium channels.

From$0.86/ tabletView

Topamax

Topiramate

25 · 50 · 100mg

Topiramate 25mg, 50mg and 100mg film-coated tablets, used in the management of epilepsy and migraine prophylaxis. It acts on several channels at once.

From$0.68/ tabletView

Trileptal

Oxcarbazepine

150 · 300 · 600mg

Oxcarbazepine 150mg, 300mg and 600mg film-coated tablets, used in the management of epilepsy. It blocks voltage-sensitive sodium channels.

From$0.67/ tabletView

Depakote

Valproic Acid

125 · 250 · 500mg

Valproic acid 125mg, 250mg and 500mg gastro-resistant tablets, used in the management of epilepsy and bipolar disorder. GABA levels rise under it.

From$0.28/ tabletView

Valparin

Valproic Acid

250 · 500 · 750mg

Valparin is valproic acid 250mg, 500mg and 750mg tablets for epilepsy, bipolar disorder and migraine prophylaxis. GABA rises, sodium channels close.

From$3.06/ tabletView

Tegretol

Carbamazepine

100 · 200 · 400mg

Carbamazepine 100mg, 200mg and 400mg tablets, used in the management of epilepsy and trigeminal neuralgia. It blocks voltage-gated sodium channels.

From$0.48/ tabletView

Mysoline

Primidone

250mg

Primidone 250mg tablets, used in the management of epilepsy. A barbiturate metabolised to phenobarbital and phenylethylmalonamide.

From$0.88/ tabletView

Depakene

Valproic Acid

250 · 750mg

Valproic acid 250mg and 750mg soft capsules, used in the management of epilepsy, bipolar disorder and migraine prophylaxis. It raises GABA in the brain.

From$2.13/ capsuleView

Divalproex Tablets

Divalproex

125 · 250 · 500mg

Divalproex 125mg, 250mg and 500mg prolonged-release tablets, used in the management of epilepsy and bipolar disorder. Sodium valproate with valproic acid.

From$0.28/ tabletView

Key points

  • Focal and generalised seizures require different medicine choices; the wrong drug can aggravate some seizure types.
  • Diagnosis relies on event history, witness or video evidence, EEG and targeted imaging, while a normal EEG does not exclude epilepsy.
  • Pregnancy potential, mood, kidney and liver health, interactions and driving or work risk all affect treatment.

The listings below are not interchangeable seizure medicines; neurological diagnosis and titration are required.

Establishing seizure type and cause

Clinicians distinguish epilepsy from fainting, sleep disorders, migraine and non-epileptic attacks. Blood tests identify provoking metabolic problems, while MRI looks for structural causes. A first seizure does not always lead to long-term medicine; recurrence risk guides the decision.

Living safely with treatment

Antiseizure medicines are selected by seizure type and gradually adjusted. Abrupt stopping can provoke prolonged seizures. Regular sleep, adherence and trigger awareness reduce risk. Preconception review is important because medicines differ in fetal risk and folic-acid planning.

When to seek urgent care

Call emergency services for a first seizure, one lasting five minutes or longer, repeated seizures without recovery, serious injury, breathing difficulty, pregnancy, or a seizure in water.

Further reading