Lamotrigine
Lamotrigine stabilises electrical signalling in the brain and is used for selected seizure disorders and bipolar disorder. It must be introduced carefully because a new rash can occasionally signal a severe reaction.
Key points
- Lamotrigine is adjusted gradually, and restarting after an interruption may require a new plan.
- Valproate and oestrogen-containing contraceptives can substantially change lamotrigine levels or response.
- A new rash with blisters, mouth sores, fever, facial swelling or swollen glands needs urgent assessment.
Select a listed product and pack to order online. Supply depends on stock and destination rules; ask your doctor or pharmacist whether it suits you.
What Lamotrigine is used for
Lamotrigine may be used alone or with other medicines for selected forms of epilepsy. It is also used to help prevent mood episodes in bipolar disorder; it is not a rapid treatment for every acute mood symptom.
How it works
Lamotrigine reduces excessive release of excitatory chemical messengers by stabilising voltage-sensitive sodium channels. The clinical effect develops as treatment is adjusted.
Important safety checks
Previous medicine rash, liver or kidney problems, pregnancy and all other antiseizure or mood medicines require review. Do not stop suddenly. If several doses have been missed, contact the prescriber before restarting rather than resuming automatically.
When to seek urgent care
Seek urgent help for a new spreading or painful rash, blistering or peeling skin, mouth or eye sores, fever with swollen glands, facial swelling, breathing difficulty, severe headache with neck stiffness, a prolonged seizure or thoughts of self-harm.
Further reading
What is lamotrigine used for?
Lamotrigine is used for some forms of epilepsy, either alone or with other medicines. It is also used to help prevent mood episodes in bipolar disorder, though it does not ease every acute mood symptom quickly.
How does lamotrigine work?
Lamotrigine calms overactive electrical signalling in the brain by blocking voltage-sensitive sodium channels, which reduces the release of excitatory chemical messengers.
Which lamotrigine product can I order on SGMeds?
The lamotrigine product on SGMeds is Lamictal, and its page gives the strengths and pack sizes.
How long does lamotrigine take to work?
The effect builds up as treatment is adjusted, so it does not work straight away. Treatment is started carefully and increased gradually.
What are the side effects of lamotrigine?
Common effects include headache, dizziness, nausea and sleepiness, and some people may notice double or blurred vision or problems with coordination. A new rash with blisters, mouth sores, fever, facial swelling or swollen glands needs urgent medical help.
Can lamotrigine be taken with other medicines?
Valproate and oestrogen-containing contraceptives can substantially change how much lamotrigine is in your body or how well it works. If you take these or other epilepsy or mood medicines, ask your doctor or pharmacist before combining them.
How is lamotrigine priced?
The product on this page shows a price for each strength and pack size in Singapore dollars, converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.
Payment and prices →Do I need a prescription for lamotrigine in Singapore?
No. SGMeds does not ask for a prescription to order lamotrigine: we place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.
Ordering without a prescription →Can I buy lamotrigine online in Singapore?
Yes, here on SGMeds: choose the product, strength and pack, then check out. Parcels go to Singapore and Malaysia by Express shipping (tracked, up to 1 week) or Regular shipping (up to 3 weeks).
How ordering works →Related articles

22 Sept 2026 ⋅ 7 min read
Bipolar Medicines Require Different Monitoring
Understand why lithium, lamotrigine, antipsychotics and valproate have different roles, interactions, pregnancy risks and monitoring needs.
Read guide