Mysoline
Primidone 250mg tablets, used in the management of epilepsy. A barbiturate metabolised to phenobarbital and phenylethylmalonamide.
- Condition
- Epilepsy
- Therapeutic class
- Antiepileptic
- Pharmacological class
- Barbiturate
- Known off-label uses
- essential tremor
- Contraindications
- hypersensitivity to primidone; porphyria
- Precautions and warnings
- avoid abrupt withdrawal; may cause drowsiness; monitor blood counts periodically
- Minor side effects
- sedation; dizziness; fatigue; ataxia
- Moderate side effects
- nystagmus; lethargy; confusion
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Concordia International
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store in dry conditions at room temperature.
- Drug interactions
- alcohol; cns depressants; valproate
- Age restrictions
- Use with caution in children.
Serious side effects
megaloblastic anaemia, requires immediate medical attention; blood dyscrasias, requires immediate medical attention
Patient summary
Primidone 250mg tablets, used in the management of epilepsy. A barbiturate metabolised to phenobarbital and phenylethylmalonamide.
Mechanism of action
Primidone is metabolized into phenobarbital and phenylethylmalonamide (PEMA), both of which possess anticonvulsant properties. They enhance GABA-mediated inhibition, suppressing excessive neuronal firing.
Pregnancy and breastfeeding
Pregnancy: Use with extreme caution. Breastfeeding: May cause sedation in infants.
Mysoline is a recognized treatment containing primidone, used for epilepsy. This product is supplied as a 250mg tablet. Individuals requiring consistent daily management for the condition often rely on this specific strength for their treatment needs.
Buying Mysoline online
Purchasing online provides a reliable pathway to maintain a consistent regimen, ensuring you have the necessary support regardless of your location.
What you will receive
Mysoline is the originator brand name, made by Concordia International. We use it here to identify the medicine only; we are not affiliated with Concordia International and do not ship the original Mysoline.
- You receive a generic equivalent: the same active ingredient (Primidone) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.