Ziac
Hydrochlorothiazide · Bisoprolol
Hydrochlorothiazide with bisoprolol as a 2.5/6.25mg film-coated tablet for hypertension. A cardioselective beta-blocker paired with a thiazide.
- Category
- Heart & Blood Pressure
- Active ingredients
- Hydrochlorothiazide · Bisoprolol
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 2.5/6.25mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Ziac on your behalf.
- Condition
- Hypertension
- Alternative names
- Lodoz
- Therapeutic class
- Beta-blocker; Thiazide Diuretic
- Pharmacological class
- Cardioselective Beta-blocker
- Precautions and warnings
- monitor electrolyte levels; avoid abrupt cessation
- Minor side effects
- fatigue; dizziness; headache; cold extremities
- Moderate side effects
- bradycardia; hypokalaemia; hyperuricaemia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Merck KGaA
- Onset Time
- 1–2 weeks
- Duration
- 24 hours
- Storage instructions
- Store in original packaging at room temperature.
- Drug interactions
- lithium; nsaids
- Age restrictions
- Not suitable for children.
- Pregnancy and breastfeeding
- Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
asthma; severely impaired hepatic function; anuria; second or third-degree heart block
Serious side effects
heart block, requires immediate medical attention; severe electrolyte imbalance, requires immediate medical attention
Patient summary
Hydrochlorothiazide with bisoprolol as a 2.5/6.25mg film-coated tablet for hypertension. A cardioselective beta-blocker paired with a thiazide.
Mechanism of action
Bisoprolol blocks beta-1 adrenergic receptors to reduce heart rate, while hydrochlorothiazide promotes excretion of water and electrolytes, reducing overall blood pressure.
Ziac provides a combination of hydrochlorothiazide and bisoprolol to manage hypertension. The same active ingredients are also marketed under the brand name Lodoz. This medication is as a tablet in the 2.5/6.25mg strength for patients requiring consistent blood pressure support.
Buying Ziac online
Because generic hydrochlorothiazide and bisoprolol, often manufactured in India, offer a more affordable route for expats, many people choose this option when far from a well stocked pharmacy.
What you will receive
Ziac is the originator brand name, made by Merck KGaA. We use it here to identify the medicine only; we are not affiliated with Merck KGaA and do not ship the original Ziac.
- You receive a generic equivalent: the same active ingredient (Hydrochlorothiazide / Bisoprolol) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.