Efudex
Fluorouracil 1% and 5% cream, applied to the skin for actinic keratosis and basal cell carcinoma. An antimetabolite that blocks thymidylate synthase.
- Categories
- Skin Care · Oncology Support
- Active ingredient
- Fluorouracil
- Route
- Cutaneous use
- Form
- Cream
- Strengths
- 1 · 5%
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Efudex on your behalf.
- Conditions
- Actinic Keratosis · Basal Cell Carcinoma
- Alternative names
- Efudix
- Therapeutic class
- Antineoplastic agent
- Pharmacological class
- Antimetabolite
- Known off-label uses
- viral warts
- Contraindications
- hypersensitivity to fluorouracil; pregnancy
- Minor side effects
- burning; stinging; erythema; pruritus
- Moderate side effects
- erosions; ulceration; dermatitis
- Serious side effects
- severe inflammatory reaction, requires immediate medical attention
- Dosage forms
- Cream
- Administration route
- Cutaneous use
- Originator
- Viatris
- Onset Time
- 2–4 weeks
- Duration
- 3–6 weeks
- Storage instructions
- Store between 15°C and 25°C.
Precautions and warnings
avoid exposure to sunlight; wash hands thoroughly after application; do not apply to mucosal surfaces
Patient summary
Fluorouracil 1% and 5% cream, applied to the skin for actinic keratosis and basal cell carcinoma. An antimetabolite that blocks thymidylate synthase.
Mechanism of action
Fluorouracil is an antimetabolite that inhibits thymidylate synthase, thereby interfering with DNA synthesis in rapidly dividing cells, which leads to the selective destruction of actinic keratosis and neoplastic skin lesions.
Pregnancy and breastfeeding
Pregnancy: Contraindicated. Breastfeeding: Not recommended due to potential systemic absorption.
Efudex is a well-known brand of Fluorouracil, used as a topical treatment for actinic keratosis and basal cell carcinoma. This medication is also available under the alternative name Efudix. It is supplied in a tube and is available in strengths of 1% and 5%.
Buying Efudex online
Generic Fluorouracil, much of which is produced in India, offers a more cost-effective alternative to the original brand. This availability benefits expats and those living in remote regions who need access to reliable dermatological care. As with any condition, this medication is best used under a doctor’s care.
What you will receive
Efudex is the originator brand name, made by Viatris. We use it here to identify the medicine only; we are not affiliated with Viatris and do not ship the original Efudex.
- You receive a generic equivalent: the same active ingredient (Fluorouracil) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.