Colcrys
Colcrys is colchicine 0.5mg tablets for gout, a tubulin inhibitor. Microtubule function in white blood cells is where it does its work.
- Category
- Pain Management
- Active ingredient
- Colchicine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 0.5mg
No prescription needed: we place your order for Colcrys on your behalf.
- Condition
- Gout
- Alternative names
- Colchimax
- Therapeutic class
- Anti-inflammatory agent
- Pharmacological class
- Tubulin inhibitor
- Known off-label uses
- familial mediterranean fever
- Precautions and warnings
- monitor for muscle pain or weakness; use with caution in elderly patients
- Minor side effects
- diarrhoea; nausea; vomiting; abdominal pain
- Moderate side effects
- fatigue; myalgia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Onset Time
- 12–24 hours
- Duration
- 24–48 hours
- Storage instructions
- Store at room temperature in a tightly closed container.
- Drug interactions
- clarithromycin; cyclosporin; statins
- Age restrictions
- Adults
Contraindications
hypersensitivity to colchicine; severe renal impairment; severe hepatic impairment
Serious side effects
rhabdomyolysis, requires immediate medical attention; pancytopenia, requires immediate medical attention
Patient summary
Colcrys is colchicine 0.5mg tablets for gout, a tubulin inhibitor. Microtubule function in white blood cells is where it does its work.
Mechanism of action
Colchicine interferes with the function of microtubules in white blood cells. By inhibiting neutrophil migration and activation at the site of inflammation, it reduces the inflammatory response associated with gout crystals.
Pregnancy and breastfeeding
Pregnancy: Not recommended unless clearly necessary. Breastfeeding: Use with caution as it is distributed into breast milk.
Colcrys is designed for the management of gout, utilising the active ingredient colchicine to prevent and control acute attacks. The same compound is also marketed under brands like Colchimax, providing a therapeutic option for patients. It is supplied as a tablet, typically available in 0.5mg strength to support specific treatment requirements.
Buying Colcrys online
For expats or travellers based far from a well stocked pharmacy, generic colchicine, frequently manufactured in India, offers a more affordable alternative to the original brand.