Kombiglyze XR
Kombiglyze XR pairs saxagliptin with metformin in a prolonged-release tablet for type 2 diabetes mellitus, a DPP-4 inhibitor alongside a biguanide.
- Category
- Diabetes Management
- Active ingredients
- Saxagliptin · Metformin
- Route
- Oral use
- Form
- Prolonged-release tablet
- Strengths
- 5/500 · 5/1000mg
No prescription needed: we place your order for Kombiglyze XR on your behalf.
Kombiglyze XR details
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- Kombiglyze
- Therapeutic class
- Dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide combination
- Pharmacological class
- Biguanide; DPP-4 inhibitor
- Contraindications
- diabetic ketoacidosis; renal impairment; hypersensitivity
- Minor side effects
- nausea; diarrhoea; gastrointestinal distress
- Moderate side effects
- urinary tract infection; headache
- Dosage forms
- Prolonged-release tablet
- Administration route
- Oral use
- Manufacturer
- AstraZeneca
- Onset Time
- 1–2 weeks
- Duration
- Ongoing
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Cimetidine
- Age restrictions
- Not for children.
- Pregnancy and breastfeeding
- Pregnancy: Use is not recommended. Breastfeeding: Not recommended.
Precautions and warnings
risk of lactic acidosis; monitor renal function; watch for symptoms of pancreatitis
Serious side effects
lactic acidosis, requires immediate medical attention; pancreatitis, requires immediate medical attention
Patient summary
Kombiglyze XR pairs saxagliptin with metformin in a prolonged-release tablet for type 2 diabetes mellitus, a DPP-4 inhibitor alongside a biguanide.
Mechanism of action
Combines a DPP-4 inhibitor to increase insulin release and a biguanide to decrease hepatic glucose production and improve insulin sensitivity.
About Kombiglyze XR
Kombiglyze XR combines Saxagliptin and Metformin to assist with the management of Type 2 Diabetes Mellitus. The same fixed-dose combination is also supplied as Kombiglyze. This medication from AstraZeneca is provided in extended-release tablet form, with available strengths ranging between 5/500 and 5/1000mg for specific requirements.
Buying Kombiglyze XR online
Generic versions containing Saxagliptin and Metformin are often significantly more affordable than the original brand, offering a practical solution for expats and those living in areas without consistent local supply.