Glucovance
Metformin with glibenclamide as a film-coated tablet, used in the management of type 2 diabetes mellitus. A biguanide paired with a sulfonylurea.
- Category
- Diabetes Management
- Active ingredients
- Metformin · Glibenclamide
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 400/2.50 · 500/5mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Glucovance on your behalf.
Glucovance details
- Condition
- Type 2 Diabetes Mellitus
- Therapeutic class
- Biguanide Antidiabetic; Sulfonylurea
- Pharmacological class
- Biguanide; Sulfonylurea
- Contraindications
- hypersensitivity; severe renal impairment; diabetic ketoacidosis; diabetic coma
- Precautions and warnings
- monitor kidney function regularly; risk of lactic acidosis
- Minor side effects
- nausea; diarrhoea; abdominal pain
- Moderate side effects
- hypoglycaemia; headache; dizziness
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Merck Serono
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store in a cool, dry place away from direct light and moisture.
- Drug interactions
- Alcohol; Cimetidine
- Age restrictions
- Not indicated for use in children.
Serious side effects
lactic acidosis, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Metformin with glibenclamide as a film-coated tablet, used in the management of type 2 diabetes mellitus. A biguanide paired with a sulfonylurea.
Mechanism of action
This medicine combines two active agents: one that lowers liver glucose production and intestinal absorption, and another that stimulates the pancreas to release more insulin. Together, they help maintain balanced blood sugar levels in patients who have not achieved adequate control through diet or exercise alone.
Pregnancy and breastfeeding
Pregnancy: Use is generally avoided; insulin is preferred for blood glucose control. Breastfeeding: Not recommended as safety data is limited.
What you will receive
Glucovance is the originator brand name, made by Merck Serono. We use it here to identify the medicine only; we are not affiliated with Merck Serono and do not ship the original Glucovance.
- You receive a generic equivalent: the same active ingredient (Metformin / Glibenclamide) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.
About Glucovance
Glucovance combines Metformin and Glibenclamide to assist in the treatment of Type 2 Diabetes Mellitus. This medication comes as a tablet in strengths of 400/2.50mg and 500/5mg. It provides an established option for individuals requiring dual-agent support to help manage blood glucose levels effectively.
Buying Glucovance online
Generic versions of Metformin and Glibenclamide, largely produced in India, provide a significantly more affordable option than the original brand for expats and travelers who find themselves far from reliable local health sources.