Glibenclamide
Glibenclamide is a sulfonylurea that lowers glucose by increasing insulin release. It can cause severe and prolonged hypoglycaemia. Listed uses include type 2 diabetes mellitus.

Glucovance
Type 2 Diabetes Mellitus
400/2.50 · 500/5mg
Metformin with glibenclamide as a film-coated tablet, used in the management of type 2 diabetes mellitus. A biguanide paired with a sulfonylurea.
Key points
- Missed meals, alcohol, illness or excess exposure can trigger low blood sugar.
- Older adults and people with kidney or liver impairment may have prolonged hypoglycaemia.
- It is not used for type 1 diabetes or diabetic ketoacidosis.
Listings are for comparison only; suitability and supply depend on diabetes assessment, prescription, glucose monitoring and pharmacy checks.
Important safety checks
Review kidney and liver function, meal pattern, alcohol, pregnancy, previous hypoglycaemia and all diabetes medicines. Know the personal low-glucose action plan.
When to seek urgent care
Seek urgent help for severe confusion, seizure, loss of consciousness or low glucose that does not respond to the action plan. Facial swelling or breathing difficulty also needs emergency care.
