Tenofovir Emtricitabine
HIV Infection, Pre-exposure Prophylaxis
300/200mg
Tenofovir with emtricitabine as a 300/200mg film-coated tablet, for HIV infection and pre-exposure prophylaxis. Two reverse transcriptase inhibitors.
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Tenofovir
Tenofovir is delivered through different prodrugs, mainly tenofovir disoproxil or tenofovir alafenamide. Products and combinations used for HIV, PrEP or hepatitis B are not automatically interchangeable.
Key points
- HIV treatment requires a complete active regimen, while PrEP requires confirmed HIV-negative status and follow-up testing.
- Kidney, bone and hepatitis B considerations differ between formulations and combination products.
- Severe weakness, very low urine output, jaundice or rapid breathing needs urgent assessment.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
What Tenofovir is used for
Tenofovir-containing products may be used in combination treatment for HIV infection, in complete PrEP regimens or for chronic hepatitis B. The exact active ingredients determine the indication.
Important form differences
Tenofovir disoproxil and tenofovir alafenamide deliver the same active antiviral inside cells but have different systemic exposure and kidney, bone and interaction profiles.
Important safety checks
HIV status, hepatitis B status, kidney function, bone health, pregnancy and all combination ingredients require review. Stopping HBV-active treatment can trigger a hepatitis flare. Do not switch formulations or stop one component without the HIV or liver team.
When to seek urgent care
Seek urgent help for marked weakness with rapid or deep breathing, very low urine output, severe bone pain after minor injury, yellow skin or eyes, severe abdominal swelling, confusion or a serious allergic reaction.