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Chlorthalidone

Chlorthalidone is a long-acting thiazide-like diuretic used to lower blood pressure or reduce selected fluid retention. It can alter sodium, potassium, kidney function and glucose. Listed uses include hypertension and oedema.

Azilsartan and Chlorthalidone Tablets

Hypertension

40/12.5mg

Azilsartan with chlorthalidone as a 40/12.5mg film-coated tablet for hypertension. An angiotensin receptor blocker paired with a thiazide-like diuretic.

From$1.35/ tabletView

Hygroton

Hypertension, Oedema

6.25 · 12.5mg

Chlorthalidone 6.25mg and 12.5mg tablets, used in the management of hypertension and oedema. A thiazide-like diuretic with a long duration.

From$0.49/ tabletView

Edarbyclor

Hypertension

40/12.5mg

Edarbyclor pairs azilsartan with chlorthalidone in a 40/12.5mg tablet for hypertension, adding renal salt and water excretion to receptor blockade.

From$1.35/ tabletView

Key points

  • Blood-pressure benefit develops with regular treatment; extra tablets are not a safe response to a high reading.
  • Low sodium or potassium can cause weakness, confusion, cramps or abnormal heart rhythm.
  • Vomiting, diarrhoea, poor fluid intake or hot weather can increase dehydration and kidney risk.

Listings are for comparison only; suitability and supply depend on clinician and pharmacy checks, prescription requirements and laboratory monitoring.

How it works

Chlorthalidone increases sodium and water excretion by the kidneys and has a prolonged blood-pressure effect.

Important safety checks

Review kidney or liver disease, gout, diabetes, low sodium or potassium, pregnancy and interacting medicines such as lithium, NSAIDs, digoxin or other blood-pressure treatments. Blood pressure, kidney function and electrolytes may need monitoring.

When to seek urgent care

Seek urgent help for fainting, severe confusion, a seizure, marked weakness, a new irregular heartbeat, very little urine, severe eye pain or facial swelling and breathing difficulty.

Further reading