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Vomiting

Vomiting is forceful expulsion of stomach contents and can result from gut infection, obstruction, migraine, pregnancy, medicines, toxins, vestibular disease or brain and metabolic disorders.

Motilium

Domperidone

10mg

Domperidone 10mg film-coated tablets, used in the management of nausea and vomiting. A peripheral dopamine antagonist that speeds gut transit.

From$0.46/ tabletView

Maxolon

Metoclopramide

10mg

Metoclopramide 10mg tablets, used in the management of nausea, vomiting and gastroparesis. A dopamine antagonist that speeds gastric emptying.

From$0.57/ tabletView

Reglan

Metoclopramide

10mg

A 10mg metoclopramide tablet for nausea, vomiting and gastroparesis, blocking dopamine at the chemoreceptor trigger zone while moving the gut along.

From$0.43/ tabletView

Compazine

Prochlorperazine

5mg

Compazine is prochlorperazine 5mg tablets for nausea, vomiting and vertigo. A phenothiazine that blocks dopamine at the chemoreceptor trigger zone.

From$0.46/ tabletView

Key points

  • Hydration status, age, pregnancy, pain, neurological symptoms and duration matter more than vomiting frequency alone.
  • Small frequent amounts of oral rehydration may help mild illness, but ongoing losses can disturb salts and kidney function.
  • Antiemetics target particular pathways and can mask deterioration, prolong QT or cause movement and other adverse effects.

Catalogue matches do not identify the cause of vomiting or indicate a safe antiemetic and dose.

What clues point to the cause?

Diarrhoea and sick contacts suggest infection, while abdominal swelling or inability to pass stool raises obstruction concern. Morning vomiting may have several causes; pregnancy testing, medicine review and neurological assessment are used where relevant.

How are antiemetics selected?

Metoclopramide, domperidone and prochlorperazine are not interchangeable. Heart rhythm, Parkinsonism, bowel obstruction, age and interactions affect suitability; see digestive health.

When to seek urgent care

Seek urgent care for vomiting blood or green fluid, severe abdominal pain or swelling, stiff neck, severe headache, confusion, head injury, very low urine, fainting or inability to keep fluids down.

Further reading