Combivir
Formulated to target HIV replication and indicated to support management of viral load in patients.
- Category
- HIV Management
- Active ingredients
- Lamivudine · Zidovudine
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 300/150mg
You will receive a quality generic equivalent, depending on stock.
Prescription rules on Combivir vary by country.
Combivir details
- Condition
- HIV Infection
- Therapeutic class
- Antiretroviral
- Pharmacological class
- NRTI
- Contraindications
- neutropaenia; severe anaemia; hypersensitivity
- Minor side effects
- nausea; headache; fatigue; diarrhoea
- Moderate side effects
- anaemia; neutropaenia; muscle pain; insomnia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Prescription medicine; local rules and pharmacy checks apply
- Originator
- ViiV Healthcare
- Onset Time
- 1–2 weeks
- Duration
- Ongoing maintenance
- Storage instructions
- Store below 30°C.
- Drug interactions
- Zalcitabine; Ribavirin; Stavudine
- Age restrictions
- Adjust dose for children by body weight.
Precautions and warnings
monitor liver function; regular blood monitoring for bone marrow suppression; avoid alcohol
Serious side effects
lactic acidosis, requires immediate medical attention; pancreatitis, requires immediate medical attention; peripheral neuropathy, requires immediate medical attention
Patient summary
Formulated to target HIV replication and indicated to support management of viral load in patients.
Mechanism of action
A combination of two nucleoside reverse transcriptase inhibitors that block the reverse transcriptase enzyme, preventing the HIV virus from converting its RNA into DNA, thus inhibiting viral reproduction.
Pregnancy and breastfeeding
Pregnancy: Use if benefit outweighs risk. Breastfeeding: Avoid due to HIV transmission risk.
What you will receive
Combivir is the originator brand name, made by ViiV Healthcare. We use it here to identify the medicine only; we are not affiliated with ViiV Healthcare and do not ship the original Combivir.
- You receive a generic equivalent: the same active ingredient (Lamivudine / Zidovudine) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.
Registration in Singapore and Malaysia
- Singapore
- Malaysia
About Combivir
Combivir combines the active ingredients lamivudine and zidovudine for the management of HIV infection. This medication is presented as a tablet in a 300/150mg strength. The combination of these two agents is designed to assist in the sustained suppression of the virus when taken as part of a daily routine.
Combivir availability in Asia
Combivir is registered across 14 markets, including Singapore, Hong Kong and Thailand, with additional availability in Malaysia, the Philippines and Indonesia. For expats and residents across these regions, consistent access to established antiretroviral therapies is a key part of long-term health. As with all treatments for HIV infection, this medication is best used under the regular guidance and monitoring of a medical professional.