Nevirapine
Nevirapine is an antiretroviral medicine used with other active medicines to treat HIV-1. It should not be used alone because resistance can develop quickly.
Key points
- Nevirapine must be part of a clinician-selected combination regimen and is not a complete HIV treatment by itself.
- Liver injury and severe skin reactions are most important early-treatment risks and require active monitoring.
- Rash with fever, mouth sores, facial swelling or yellow skin or eyes needs urgent assessment.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
What Nevirapine is used for
Nevirapine may be used within combination treatment for HIV infection. Selection depends on resistance history, previous treatment, liver health, interactions and the other medicines in the regimen.
How it works
Nevirapine blocks HIV reverse transcriptase, reducing the virus’s ability to copy its genetic material. A combination of active medicines is needed to achieve and maintain viral suppression.
Important safety checks
Liver tests and skin symptoms need close review after treatment starts. Pregnancy, hepatitis, all current medicines and prior antiretroviral exposure can affect the plan. Do not stop only one component, restart after an interruption or switch the regimen without the HIV care team.
When to seek urgent care
Seek urgent help for a painful or blistering rash, peeling skin, mouth or eye sores, rash with fever or swollen glands, facial swelling, breathing difficulty, yellow skin or eyes, dark urine, severe abdominal pain or marked weakness.