Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic for selected infections caused by susceptible bacteria. It is generally reserved for situations where safer suitable options are not appropriate.
Key points
- Levofloxacin does not treat viral illness, and bacterial diagnosis, local resistance and kidney function affect selection.
- Tendon injury, peripheral nerve damage, serious neurological effects and heart-rhythm changes can occur.
- Tendon pain or swelling, new numbness or weakness, severe confusion or fainting needs prompt medical assessment.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
What Levofloxacin is used for
Levofloxacin may be prescribed for selected bacterial infections, including some cases of prostatitis, when the suspected or confirmed organism and patient factors support its use.
How it works
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, preventing susceptible bacteria from copying and repairing DNA.
Important safety checks
Previous fluoroquinolone reactions, tendon disorders, neuropathy, seizure risk, myasthenia gravis, heart-rhythm problems, diabetes, aortic disease and kidney function require review. Antacids and mineral supplements can reduce absorption, while corticosteroids can increase tendon risk. Complete the prescribed course unless a clinician advises stopping because of a serious reaction.
When to seek urgent care
Stop and seek prompt advice for tendon pain or swelling, new burning, tingling, numbness or weakness, severe mood or behaviour change, or marked blood-glucose symptoms. Seek emergency help for fainting, seizure, severe allergic reaction or sudden severe chest, back or abdominal pain.
Further reading
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