Hydroquinone Cream
Hyperpigmentation
4%
Hydroquinone 4% cream, applied to the skin for hyperpigmentation. A tyrosinase inhibitor that interrupts the first step of melanin formation.
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Hydroquinone
Hydroquinone is a topical depigmenting medicine used for selected localised hyperpigmentation after assessment. It should not be used for general skin bleaching or an undiagnosed changing lesion. Results vary and recurrence can occur.
Key points
- Diagnosis matters because melanoma and other lesions can be mistaken for pigmentation.
- Prolonged or inappropriate use can cause paradoxical blue-black darkening called exogenous ochronosis.
- Sun protection is central because ultraviolet exposure can worsen pigmentation and undermine treatment.
Listings are for comparison only; suitability depends on diagnosis, concentration, formulation and clinician or pharmacy checks.
Important safety checks
Review pregnancy, breastfeeding, sensitive or broken skin, other irritating products and prior ochronosis. Avoid eyes and mucous membranes and stop if marked irritation develops.
When to seek urgent care
Seek urgent help for facial swelling or breathing difficulty. Prompt dermatology assessment is needed for a rapidly changing, bleeding or irregular pigmented lesion or severe blistering.