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Cyproheptadine

Cyproheptadine is a first-generation antihistamine used for selected symptoms of allergic rhinitis or urticaria. It can cause substantial drowsiness and anticholinergic effects.

Periactin

Allergic Rhinitis, Urticaria

4mg

Cyproheptadine 4mg tablets, used for allergic rhinitis and urticaria. A first-generation antihistamine that also blocks serotonin at its receptors.

From$0.48/ tabletView

Key points

  • Cyproheptadine may reduce allergy symptoms but does not replace emergency treatment for anaphylaxis.
  • Alcohol, sedatives, glaucoma, urinary retention and breathing disease require review.
  • Throat swelling, breathing difficulty, collapse or severe confusion needs urgent care.

Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.

How it works

Cyproheptadine blocks histamine H1 receptors and also has antiserotonin and anticholinergic activity.

Important safety checks

Narrow-angle glaucoma, urinary or bowel obstruction, enlarged prostate, severe asthma symptoms and use of monoamine-oxidase inhibitors require review. Avoid alcohol and driving until individual alertness is known. Appetite or weight concerns should be assessed rather than treated without a clear indication.

When to seek urgent care

Use the prescribed emergency allergy plan and seek emergency help for tongue or throat swelling, wheezing, breathing difficulty, fainting or collapse. Severe agitation, confusion, hallucinations, high fever or inability to urinate also needs urgent assessment.

Further reading