Colestyramine
Colestyramine is a non-absorbed resin that binds bile acids in the intestine. This can lower LDL cholesterol or reduce selected bile-related itching, but it can also reduce absorption of other medicines.
Key points
- Other oral medicines often need to be separated from colestyramine according to product and pharmacist instructions.
- Constipation can worsen and may become severe, particularly in people with existing bowel problems.
- Long-term use can reduce absorption of fat-soluble vitamins and requires condition-specific review.
Listings are for comparison only; suitability and supply depend on the indication, other medicines, prescription and clinician or pharmacy checks.
What colestyramine is used for
Uses may include selected hypercholesterolaemia or bile-acid-related pruritus. It does not treat every cause of itching or high triglycerides.
How it works
Colestyramine binds bile acids in the gut so they leave the body in stool. It can bind medicines and nutrients at the same time.
Important safety checks
Review bowel obstruction or severe constipation, high triglycerides, swallowing problems, pregnancy and every oral medicine or supplement. Mix and take only as the product directs; dry powder should not be swallowed on its own.
When to seek urgent care
Seek urgent help for severe abdominal pain or swelling, repeated vomiting, inability to pass stool or gas, choking, facial swelling or breathing difficulty.