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Clavulanic Acid

Clavulanic acid inhibits selected bacterial beta-lactamases and is used with a penicillin antibiotic. The active combination, not clavulanic acid alone, determines treatment.

Augmentin

Bacterial Infection

250/125 · 500/125 · 750/250 · 875/125mg

Amoxicillin with clavulanate in four film-coated tablet strengths, used for bacterial infection. Clavulanate stops bacteria breaking the antibiotic down.

From$1.62/ tabletView

Advent DT

Bacterial Infection

400/57mg

Advent DT is amoxicillin with clavulanic acid as a 400/57mg dispersible tablet, used for bacterial infection. Clavulanic acid blocks beta-lactamase.

From$2.13/ tabletView

Key points

  • Clavulanic acid expands activity against selected beta-lactamase-producing bacteria but does not overcome all antibiotic resistance.
  • The companion antibiotic, formulation and ingredient ratio must match the prescription.
  • Liver injury and antibiotic-associated diarrhoea are important combination-product risks.

Listings are for comparison only; suitability and supply depend on the complete antibiotic product, bacterial infection, prescription and pharmacy checks.

What clavulanic acid is used for

It is paired with a penicillin for selected bacterial infections. It should not be selected separately or used for viral illness.

How it works

Clavulanic acid binds to selected beta-lactamase enzymes, protecting the companion penicillin from breakdown.

Important safety checks

Review severe beta-lactam allergy, previous combination-related jaundice or liver injury, liver or kidney disease, pregnancy, anticoagulants and previous antibiotic-associated colitis.

When to seek urgent care

Seek urgent help for facial swelling, breathing difficulty, blistering skin, yellow skin or eyes, dark urine, severe abdominal pain, or severe or bloody diarrhoea.

Further reading