Bempedoic Acid
Bempedoic acid lowers LDL cholesterol by reducing cholesterol production in the liver. It may be used alongside diet and other lipid-lowering treatment after cardiovascular risk and treatment tolerance are reviewed. Listed uses include primary hypercholesterolaemia and mixed dyslipidaemia.
Key points
- Bempedoic acid lowers LDL cholesterol but does not replace management of smoking, blood pressure, diabetes or diet.
- Gout, high uric acid, tendon disorders and interactions with some statins require review.
- Sudden tendon pain or swelling, inability to bear weight or a severe allergic reaction needs prompt care.
Select a listed product and pack to order online. Supply depends on stock and destination rules; ask your doctor or pharmacist whether it suits you.
How it works
Bempedoic acid inhibits ATP citrate lyase, an enzyme earlier in the liver’s cholesterol-production pathway than the enzyme blocked by statins.
Important safety checks
Uric acid, gout history, tendon injury, liver function and the exact statin regimen need review. Report new tendon discomfort early and avoid strenuous use of the affected area until assessed.
When to seek urgent care
Seek prompt care for a snap or pop with sudden tendon pain, swelling or inability to move or bear weight. Seek urgent help for facial swelling, breathing difficulty or severe widespread rash.
Further reading
What is bempedoic acid used for?
Bempedoic acid lowers LDL cholesterol in people with high cholesterol or mixed dyslipidaemia, alongside diet and other lipid-lowering treatment.
How does bempedoic acid work?
Bempedoic acid blocks an enzyme called ATP citrate lyase in the liver. This enzyme sits earlier in the cholesterol-production pathway than the enzyme statins block, so less LDL cholesterol is made.
Which product contains bempedoic acid?
The bempedoic acid product on SGMeds is Nexletol, and its page gives the strengths and pack sizes.
What is bempedoic acid called in other countries?
In other countries, bempedoic acid is also sold as Nilemdo. Brand names vary between countries, so compare products by their active ingredient.
How long does bempedoic acid take to work?
Bempedoic acid can take 2 to 4 weeks before its full effect shows.
What are the side effects of bempedoic acid?
Common side effects include high uric acid levels (hyperuricaemia), muscle spasms, back pain and abdominal pain. Gout, anaemia and increased liver enzymes have also been reported. Tendon rupture is serious and needs immediate medical attention.
Can bempedoic acid be taken with other medicines?
Bempedoic acid interacts with simvastatin and pravastatin, so if you take either of these statins, ask a doctor or pharmacist before you use it.
How is bempedoic acid priced?
The product on this page shows a price for each strength and pack size in Singapore dollars, converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.
Payment and prices →Can I buy bempedoic acid over the counter in Singapore?
Yes, online. SGMeds does not ask for a prescription to order bempedoic acid: we place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.
Ordering without a prescription →Where can I buy bempedoic acid in Singapore?
You can order bempedoic acid here on SGMeds: choose the product, strength and pack, then check out. We deliver to Singapore and Malaysia. Express shipping is tracked and takes up to 1 week, and Regular shipping takes up to 3 weeks.
How ordering works →