Buy Lopid
lopid
$69.00
- Active ingredient: Gemfibrozil
- Category: Cholesterol Management
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Lopid (Gemfibrozil) 300mg tablets are available to order from our Singapore pharmacy with reliable delivery. This fibrate medication works by reducing triglyceride production in the liver and increasing HDL cholesterol levels, providing targeted lipid management. It is particularly effective for adults with high triglyceride levels who require specialized treatment beyond standard statin therapy for comprehensive cardiovascular protection.
Table of contents
- Lopid (Gemfibrozil) Buyer and Patient Handbook in Singapore
- What is Lopid?
- Who Should Use Lopid?
- How Does It Work?
- Why Choose Lopid?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Lopid Alternatives
- Frequently Asked Questions
- How quickly will Lopid lower my triglycerides?
- Can I drink coffee while taking Lopid?
- Is it safe to exercise while on Lopid?
- What should I do if I experience mild stomach upset?
- Does Lopid interact with over-the-counter vitamins?
- Can I take Lopid together with a statin?
- What happens if I miss several doses in a row?
- Is Lopid covered by the MediSave scheme?
- Will Lopid affect my blood sugar levels?
- Can I travel with Lopid overseas?
- Glossary
- Disclaimer
- Lopid Properties
- Lopid Drug Class
- Lopid Connected Conditions
- How to order Lopid from our Online Pharmacy
- Reviews
- Write your review
Lopid (Gemfibrozil) Buyer and Patient Handbook in Singapore
What is Lopid?
Lopid (Gemfibrozil) is a lipid-modifying oral medication classified as a fibric acid derivative. It is primarily prescribed to lower elevated triglyceride levels and to raise high-density lipoprotein (HDL) cholesterol. The drug is approved by the Health Sciences Authority (HSA) in Singapore and is available as a 300 mg tablet.
Who Should Use Lopid?
- Adults with severe hypertriglyceridaemia (triglycerides > 500 mg/dL)
- Patients who have not achieved target lipid levels with diet and lifestyle alone
- Individuals at risk of pancreatitis due to High Triglycerides
- Those whose primary goal is to increase HDL-C
How Does It Work?
Lopid activates peroxisome proliferator-activated receptor-α (PPAR-α), a nuclear receptor that regulates genes involved in fatty-acid metabolism. Activation speeds up the breakdown of triglyceride-rich particles and boosts the liver’s ability to clear them from the bloodstream. Think of it as turning up the engine that “burns” excess fats, similar to how a car’s turbocharger increases performance.
Why Choose Lopid?
- Proven efficacy for reducing triglycerides and modestly raising HDL-C.
- Rapid onset of action-significant lipid changes can be seen within 2-4 weeks.
- For patients who cannot tolerate statins or need additional triglyceride control, Lopid offers a complementary option.
Note: Off-label uses (e.g., primary prevention of cardiovascular events) should only be considered after discussing potential benefits and risks with a qualified healthcare professional.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Standard adult dose: 300 mg tablet taken twice daily, 30 minutes before the first main meal of the day.
How to Take
- Swallow the tablet whole with a glass of water.
- Take the first dose before breakfast and the second before dinner.
- Do not crush or split the tablet.
Missed Dose
- If you remember within 2 hours, take the missed dose.
- If it’s later than 2 hours, skip it and continue with the regular schedule. Do not double-dose.
Overdose
- Seek immediate medical attention or call emergency services.
- Symptoms may include Nausea, Vomiting, abdominal Pain, or muscle weakness.
Special Populations
- Elderly: No dose adjustment required, but monitor renal function.
- Renal impairment: Use with caution; dose may need reduction if creatinine clearance < 30 mL/min.
- Pregnancy & lactation: Generally avoided; discuss alternatives with your clinician.
Lifestyle & Diet
- Avoid large meals high in saturated fat during the first hour after dosing.
- Limit alcohol as it can increase triglyceride levels and raise the risk of pancreatitis.
- Grapefruit juice does not significantly interact, but maintain consistent intake.
- Continue a heart-healthy diet (high fiber, omega-3 rich fish, reduced simple sugars).
Precautions and Warnings
- Liver function: Baseline and periodic liver enzymes are recommended.
- Kidney function: Monitor serum creatinine, especially in patients with pre-existing renal disease.
- Gallstones: May increase the risk; report any abdominal pain or jaundice promptly.
- Muscle toxicity: Rare, but watch for unexplained Muscle Pain, weakness, or dark urine.
Drug Interactions
| Drug Class | Risk | Action |
|---|---|---|
| Statins (e.g., simvastatin) | Increased muscle toxicity | Use low-dose statin; monitor CK. |
| Anticoagulants (warfarin) | Enhanced anticoagulation | Check INR more frequently. |
| Thiazide diuretics | Elevated serum uric acid | Monitor uric acid; consider gout prophylaxis. |
Potential Side Effects
Common Side Effects
- Gastrointestinal upset (nausea, dyspepsia)
- Mild abdominal pain
- Diarrhoea
Less Common Side Effects
- Headache
- Dizziness
- Elevated liver enzymes
Serious Side Effects
- Pancreatitis: Sudden severe abdominal pain, vomiting. Seek medical help immediately.
- Severe allergic reaction: Rash, swelling, difficulty breathing. Call emergency services.
- Myopathy or rhabdomyolysis: Muscle pain, weakness, dark urine. Stop the drug and obtain urgent care.
Who Should Avoid This Medication?
- Known hypersensitivity to gemfibrozil or any component of the tablet.
- Active liver disease (elevated transaminases > 3× ULN).
- Severe renal impairment (creatinine clearance < 30 mL/min) without specialist guidance.
Storage Instructions
- Keep tablets below 30 °C, away from direct sunlight.
- Store in the original container, tightly closed, out of reach of children.
- Do not use after the expiry date printed on the pack.
Lopid Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Fenofibrate | Fibric acid | Longer half-life; once-daily dosing. |
| Omega-3 fatty acids (EPA/DHA) | Marine oil | Non-prescription, modest triglyceride reduction. |
| Statins (e.g., atorvastatin) | HMG-CoA reductase inhibitor | Primary LDL-C lowering; may need combination for triglycerides. |
Frequently Asked Questions
How quickly will Lopid lower my triglycerides?
Most patients see a 15-30 % reduction within the first 2 weeks, with maximal effect at 4-6 weeks.
Can I drink coffee while taking Lopid?
Yes, moderate coffee intake does not affect the drug’s efficacy.
Is it safe to exercise while on Lopid?
Regular aerobic exercise is encouraged; it synergistically improves lipid profiles.
What should I do if I experience mild stomach upset?
Take the tablet with a small amount of food and consider an antacid if needed, but continue the medication unless symptoms persist.
Does Lopid interact with over-the-counter vitamins?
Low-dose multivitamins are generally safe; however, high-dose niacin may increase the risk of flushing and liver enzyme elevation.
Can I take Lopid together with a statin?
Yes, but the combination raises the risk of muscle toxicity; a low-dose statin is usually recommended and liver enzymes should be monitored.
What happens if I miss several doses in a row?
Contact a healthcare professional for guidance; you may need a temporary dose adjustment.
Is Lopid covered by the MediSave scheme?
Lopid is listed under the Approved Medicines List (AML); eligibility depends on individual MediSave contributions and prescription status.
Will Lopid affect my blood sugar levels?
Gemfibrozil has minimal impact on glucose metabolism, but regular monitoring is advised for diabetic patients.
Can I travel with Lopid overseas?
Yes, keep the medication in its original packaging, carry a copy of the prescription (if required by customs), and store it at room temperature.
Glossary
- Triglycerides: The main form of fat stored in the body; high levels increase pancreatitis risk.
- HDL-C: “Good” cholesterol that helps remove excess cholesterol from arteries.
- PPAR-α: A protein that regulates genes involved in fat metabolism, targeted by fibric acids.
Disclaimer
The information provided here is for general educational purposes only and does not substitute professional medical advice. Lopid may be used off-label only after a qualified healthcare professional evaluates the risks and benefits. Our online pharmacy platform offers convenient access to medications, but users are responsible for ensuring that any medication they obtain is appropriate for their health condition. Always consult a licensed clinician before starting, stopping, or changing any medication regimen.
Lopid Properties
- Original Manufacturer: Pfizer
- Clinical use: Reduction of triglycerides and LDL cholesterol
- Spectrum of activity: Fibrate
- Mechanism of action: Increases lipoprotein lipase activity, reducing triglycerides and LDL
- Classification: Fibrate
- Recommended Dosage: 600 mg twice daily
- Basic Side Effects: Abdominal pain, Muscle pain, Headache
- Moderate Side Effects: Increased liver enzymes
- Serious Side Effects: Rhabdomyolysis, Severe liver dysfunction
Lopid Drug Class
Lopid Connected Conditions
How to order Lopid from our Online Pharmacy
To order Lopid | Gemfibrozil on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Lopid / Gemfibrozil pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Lopid pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Just started the 300mg Lopid pill for my crazy high triglycerides. My first week has been rough. The abdominal cramping is no joke and I feel constantly bloated. It reminds me a bit of a bad food poisoning episode, but less intense. The nurse told me this usually settles down by week two. Really hoping that’s true, because right now, I dread taking the second dose of the day. Results aren't in yet, so keeping my fingers crossed this pain isn't for nothing.
Been on Gemfibrozil 300mg now for almost three years. Lipids are definitely under control, HDL improved significantly. This drug works, period. BUT, you absolutely cannot miss the food requirement. If you take this thing on an even slightly empty stomach, get ready for nausea and maybe the worst gas of your life. My hack: Always take it with a full meal, preferably dinner, and a glass of milk to buffer it. Saved me many times!
This medication lowered my VLDL fantastically, which is the main win here. Trade-off? I definitely think it contributes to muscle aches. Not full-blown rhabdo, but a persistent, dull ache in my thighs and lower back that wasn't there before. I discussed splitting the 300mg twice daily dose with my GP-taking 150mg x 4 times a day-to try and keep serum levels more stable and mitigate the peak body load. Too early to tell if the hack helps.
Trying to bring my tri levels down urgently, and Lopid is the one my specialist prescribed. I feel like my gallbladder is protesting! Severe upper right quadrant pain when I eat anything remotely fatty. It works quickly to improve the numbers, I'll give it that. But the severe digestive upset makes me question if I can stay on this long-term. Anyone else experience extreme, almost sudden constipation starting this pill?
I’ve been taking Gemfibrozil for almost 10 years now. It does its job better than statins did for me personality, with fewer mental fog issues, which is why I stuck with it. The number one long-term side effect that nobody seems to mention is the dry mouth. It’s constant. I carry water everywhere. Pro Tip: Use specific dry mouth lozenges (Xylitol ones) religiously, especially before sleeping, or you wake up feeling like you swallowed sand.
My liver enzymes started looking dicey on this 300mg dose after six months, which sucks because my triglycerides were absolutely perfect for the first time in years. The numbers were great, but the internal health markers were worrying the doctor. So, it worked for my lipid panel, but seemingly stressed my liver. Now I have to switch to something else. It's always a trade-off, isn't it?
The weirdest thing about Lopid is the metallic taste that comes and goes. Like sucking on old coins. It’s a very intermittent but persistent side effect for me, after about five months on the drug. My lipid profile is fantastic now, so the benefits outweigh the weird taste. I started chewing strong mint gum immediately after taking the pill, which is the only thing that masks the taste successfully for an hour or so, letting me eat breakfast normally.
I originally took it at night hoping to sleep through the stomach ache, but that was a mistake. I ended up with restless legs syndrome (RLS) keeping me awake. Switched to taking it right with my lunch and early afternoon dose. RLS went away almost immediately. My triglycerides are down by 40%, excellent result. So, great drug, but the timing is everything. Do NOT take this anywhere near bedtime if you are prone to RLS.