Sorafenib
Sorafenib is a targeted cancer medicine that blocks several kinases involved in tumour growth and blood-vessel formation. Treatment requires oncology monitoring and early reporting of toxicity. Listed uses include hepatocellular carcinoma, renal cell carcinoma and differentiated thyroid carcinoma.
Key points
- Sorafenib selection depends on cancer type, stage, liver function, prior treatment and treatment goals.
- Blood pressure, skin and hand-foot symptoms, bleeding, heart function and wound healing require review.
- Chest pain, severe bleeding, bowel-perforation symptoms or a blistering rash needs urgent care.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
How it works
Sorafenib inhibits RAF and several receptor tyrosine kinases involved in cancer-cell signalling and tumour angiogenesis.
Important safety checks
Blood pressure, liver function, bleeding and clot risk, heart disease, skin toxicity, pregnancy, planned surgery and interacting medicines require review. Hand-foot pain, redness or blistering should be reported early before it limits walking or hand use.
When to seek urgent care
Seek urgent help for chest pain, sudden breathlessness, stroke signs, vomiting blood, black stools, severe abdominal pain with fever, extensive blistering skin, fainting or severe uncontrolled blood-pressure symptoms.