Sacubitril
Sacubitril is a neprilysin inhibitor used only in a fixed combination for selected heart failure. Listed uses include Chronic Heart Failure.
Key points
- Sacubitril is not used alone; the complete combination product determines treatment.
- It must be separated appropriately from ACE inhibitors because angioedema risk rises.
- Facial swelling, fainting or severe weakness needs urgent care.
Listings are for comparison and general information; suitability and supply depend on clinician and pharmacy checks, monitoring and prescription requirements.
Important safety checks
Exact combination, prior angioedema, pregnancy, kidney function, potassium and interacting renin-angiotensin medicines require review.
When to seek urgent care
Seek urgent help for facial or throat swelling, breathing difficulty, fainting, severe weakness or very little urine.