Sacubitril
Sacubitril is a neprilysin inhibitor used only in a fixed combination for selected heart failure. Listed uses include Chronic Heart Failure.
Key points
- Sacubitril is not used alone; the complete combination product determines treatment.
- It must be separated appropriately from ACE inhibitors because angioedema risk rises.
- Facial swelling, fainting or severe weakness needs urgent care.
Select a listed product and pack to order online. Ask your doctor or pharmacist whether it suits you and what monitoring it needs.
Important safety checks
Exact combination, prior angioedema, pregnancy, kidney function, potassium and interacting renin-angiotensin medicines require review.
When to seek urgent care
Seek urgent help for facial or throat swelling, breathing difficulty, fainting, severe weakness or very little urine.