Ribavirin
Ribavirin is an antiviral used as one component of selected treatment regimens. It can cause severe fetal harm and haemolytic anaemia, so treatment requires strict pregnancy precautions and clinical monitoring.
Key points
- Ribavirin is not used alone for hepatitis C and is not suitable for every antiviral regimen.
- Pregnancy must be avoided when either the patient or a male patient’s partner could be exposed during the defined risk period.
- Destruction of red blood cells can cause significant anaemia and may worsen heart problems.
Listings are for comparison only; suitability and supply depend on specialist prescribing, the complete antiviral regimen, pregnancy controls and pharmacy checks.
What ribavirin is used for
Ribavirin may be used with other medicines in selected treatment of chronic hepatitis C or certain other viral infections. The regimen depends on the virus, disease stage, kidney function and previous treatment.
How it works
Ribavirin interferes with processes viruses use to reproduce, but its mechanism and benefit depend on the accompanying antiviral regimen.
Important safety checks
Pregnancy testing and effective contraception may be required for patients and partners according to the treatment programme. The team should review blood counts, kidney and liver function, heart disease and interacting antiviral medicines. Do not donate blood while pregnancy-risk restrictions apply.
When to seek urgent care
Seek urgent help for chest pain, severe breathlessness, fainting, marked weakness, a very fast heartbeat, facial swelling or breathing difficulty. Contact the specialist team promptly about possible pregnancy exposure, dark urine, jaundice or a major decline in energy.