Moxifloxacin
Moxifloxacin is a fluoroquinolone antibiotic for selected infections caused by susceptible bacteria. Its heart-rhythm and other class-specific risks must be weighed against suitable alternatives.
Key points
- Moxifloxacin does not treat viral illness and should be selected using the infection site, likely bacteria and resistance information.
- Heart-rhythm effects, tendon injury, peripheral nerve damage and serious neurological effects are important risks.
- Fainting, a fast or irregular heartbeat, tendon swelling or new numbness or weakness needs prompt assessment.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
What Moxifloxacin is used for
Moxifloxacin may be used for selected cases of bacterial pneumonia, acute sinusitis or complicated skin and soft-tissue infection when other appropriate options are unsuitable.
How it works
Moxifloxacin blocks bacterial DNA gyrase and topoisomerase IV, preventing susceptible bacteria from copying and repairing DNA.
Important safety checks
Long-QT syndrome, low potassium or magnesium, interacting heart-rhythm medicines, previous fluoroquinolone reactions, tendon disorders, neuropathy, seizure risk, myasthenia gravis, diabetes and aortic disease require review. Antacids and mineral supplements can reduce absorption. Complete the prescribed course unless a clinician advises stopping because of a serious reaction.
When to seek urgent care
Stop and seek prompt advice for tendon pain or swelling, new burning, tingling, numbness or weakness, severe mood or behaviour change, or marked blood-glucose symptoms. Seek emergency help for fainting, a sustained fast or irregular heartbeat, seizure, severe allergic reaction or sudden severe chest, back or abdominal pain.