Entacapone
Entacapone is a COMT inhibitor used with levodopa in Parkinson’s disease.
Key points
- It has no useful antiparkinsonian effect without levodopa.
- It can intensify dyskinesia, low blood pressure or hallucinations.
- Severe rigidity with fever or dangerous behaviour needs urgent care.
Listings are for comparison and general information; suitability and supply depend on clinician and pharmacy checks, monitoring and prescription requirements.
Important safety checks
Liver health, diarrhoea, hallucinations, impulse changes and all Parkinson medicines require review.
When to seek urgent care
Seek urgent help for high fever with rigidity, severe confusion, fainting, suicidal intent or persistent severe diarrhoea.