Conjugated Oestrogens
Conjugated oestrogens are a mixture of oestrogen hormones used for selected menopausal or oestrogen-deficiency indications. Systemic and vaginal products have different exposure and risk considerations. Listed uses include menopausal symptoms and oestrogen deficiency.
Key points
- A person with a uterus may need progestogen protection with systemic oestrogen to reduce endometrial overgrowth and cancer risk.
- Systemic treatment can increase blood-clot and stroke risk, with suitability shaped by personal history and route.
- New or unexplained vaginal bleeding requires assessment rather than an independent treatment change.
Listings are for comparison only; suitability and supply depend on indication, route, individual risk assessment, prescription and pharmacy checks.
How they work
Conjugated oestrogens activate oestrogen receptors in multiple tissues. Route affects how much medicine reaches the rest of the body.
Important safety checks
Review unexplained bleeding, uterus status, pregnancy, blood clots, stroke, migraine, liver disease, breast or endometrial cancer risk, smoking and interacting medicines. Screening and review needs depend on the individual plan.
When to seek urgent care
Seek urgent help for chest pain, sudden breathlessness, coughing blood, one-sided leg swelling, signs of stroke, sudden vision loss, severe headache, facial swelling or breathing difficulty.