Celecoxib
Celecoxib is a COX-2-selective non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. Selectivity does not remove cardiovascular, kidney or gastrointestinal risk. Listed uses include osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Key points
- Celecoxib can increase heart attack or stroke risk and is not suitable around coronary bypass surgery.
- Stomach or intestinal ulceration and bleeding can occur, especially with anticoagulants, antiplatelets or other NSAIDs.
- Kidney disease, dehydration, heart failure, high blood pressure and pregnancy can materially affect suitability.
Listings are for comparison only; suitability and supply depend on clinician and pharmacy checks, prescription requirements and other pain medicines.
How it works
Celecoxib preferentially inhibits COX-2, reducing prostaglandins involved in pain and inflammation. It should not be combined with another NSAID unless specifically directed.
Important safety checks
Review heart disease, stroke, ulcers or bleeding, kidney or liver disease, asthma triggered by aspirin or NSAIDs, pregnancy and sulfonamide reactions. Check anticoagulants, antiplatelets, blood-pressure medicines and other NSAIDs.
When to seek urgent care
Seek urgent help for chest pain, sudden weakness, vomiting blood, black stools, severe abdominal pain, very little urine, blistering skin, facial swelling or breathing difficulty.
Further reading
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