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Severe Acne

Severe acne involves widespread inflammation, deep nodules or cysts, or substantial scarring risk. Early clinical assessment can limit permanent marks and address the psychological burden.

Isofair

Isotretinoin

10 · 20mg

Isofair is isotretinoin 10mg and 20mg soft capsules for severe, conglobate and cystic acne, a systemic retinoid that shrinks the sebaceous glands.

From$1.17/ tabletView

Tretiva

Isotretinoin

5 · 10 · 20 · 30mg

Tretiva is isotretinoin from 5mg to 30mg in soft capsules for severe, nodulocystic and cystic acne, cutting sebaceous gland activity and size.

From$0.98/ tabletView

Isotroin

Isotretinoin

10 · 20mg

Isotroin is isotretinoin 10mg and 20mg soft capsules for acne vulgaris and severe cystic acne, a retinoid that cuts sebum at its source.

From$1.17/ tabletView

Key points

  • Deep painful lesions, draining tracts, widespread trunk involvement or active scarring indicate disease beyond simple comedonal acne.
  • Acne severity, pregnancy potential, medicines, hormonal features, mental health and previous treatment guide the plan.
  • Isotretinoin can be effective for selected severe acne but requires strict pregnancy prevention where relevant and adverse-effect monitoring.

Catalogue matches do not establish acne severity or show that an oral retinoid or hormone treatment is suitable.

What causes deep inflammatory lesions?

Follicle blockage, sebum, Cutibacterium acnes and inflammation interact. Hormones and genetics may contribute, but severe acne is not proof of poor hygiene or a specific diet. Picking or squeezing increases tissue damage.

How is treatment escalated?

A clinician may combine appropriate topical treatment with oral therapy and scar prevention. Isotretinoin has major fetal risk and other monitoring needs. Hormonal options are selected according to clot risk and individual health, not solely because acne occurs around cycles. See skin care.

When to seek urgent care

Seek prompt care for rapidly worsening painful disease with fever, large areas of skin breakdown or severe mood change. Suspected pregnancy while taking isotretinoin requires immediate prescriber contact.

Further reading