Buy Zofran
zofran
$36.90
- Active ingredient: Ondansetron
- Category: Oncology Support | Digestive Health
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Zofran (Ondansetron) tablets are available to order from our Singapore pharmacy with reliable delivery. This selective serotonin 5-HT3 receptor antagonist works by blocking the chemical signals that trigger nausea and vomiting in the brain and gut. It provides targeted relief for chemotherapy-induced nausea, postoperative sickness, and radiation-related vomiting. Zofran is an ideal solution for patients undergoing cancer treatment or surgical procedures who need effective antiemetic protection.
Table of contents
- Zofran (Ondansetron) Buyer and Patient Handbook in Singapore
- What is Zofran?
- Who Should Use Zofran?
- How Does It Work?
- Why Choose Zofran?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Zofran Alternatives
- Frequently Asked Questions
- How long does Zofran start working?
- Can I take Zofran on an empty stomach?
- Is Zofran safe for patients with liver disease?
- Will Zofran cause drowsiness?
- Can I drink coffee while on Zofran?
- What should I do if I experience a rapid heartbeat?
- Is Zofran covered by Singapore’s MediShield Life?
- Can I use Zofran for motion sickness?
- Glossary
- Disclaimer
- Zofran Properties
- Zofran Drug Class
- Zofran Connected Conditions
- How to order Zofran from our Online Pharmacy
- Reviews
- Write your review
Zofran (Ondansetron) Buyer and Patient Handbook in Singapore
What is Zofran?
Zofran is an oral anti-emetic belonging to the serotonin-5-HT₃-receptor antagonist class, used to prevent Nausea and Vomiting caused by chemotherapy, radiotherapy, or surgery. It is approved by both the Health Sciences Authority (HSA) and the FDA. Zofran is supplied as a tablet (pill) in 4 mg and 8 mg strengths.
Who Should Use Zofran?
- Adults undergoing chemotherapy or radiotherapy.
- Patients scheduled for surgery who are at risk of post-operative nausea.
- Individuals receiving high-dose opioid therapy who experience nausea.
- Patients with a history of severe nausea not controlled by other measures (under medical guidance).
How Does It Work?
Zofran blocks serotonin receptors in the gut and the brain’s vomiting centre, stopping the signal that triggers nausea. Think of it as putting a “do not disturb” sign on the pathways that cause the brain to feel sick. It has a low potential for abuse, but should be used only as directed.
Why Choose Zofran?
- Rapid relief: Onset of action usually within 30 minutes, with effect lasting up to 5 hours.
- Convenient dosing: Available in two strengths, making dose adjustment simple.
- Well-studied: Extensive clinical data support its safety and efficacy in cancer-support care. Off-label uses exist, but any such use should be discussed with a healthcare professional.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- 4 mg tablet: One dose taken 30 minutes before chemotherapy, then every 8 hours as needed.
- 8 mg tablet: One dose taken 30 minutes before chemotherapy, then every 12 hours as needed.
How to Take
- Swallow the tablet whole with a full glass of water.
- It can be taken with or without food; choose whichever is more comfortable for you.
Missed Dose
- If you remember within 2 hours, take the missed dose.
- If more than 2 hours have passed, skip it and resume the regular schedule.
Overdose
- Call the Singapore Poison Centre (24-hour hotline: 180-222-111) immediately.
- Seek urgent medical attention; supportive care is the main treatment.
Special Populations
- Elderly: Use the lowest effective dose; monitor for constipation.
- Renal or hepatic impairment: Dose reduction may be required; consult a clinician.
- Pregnancy & breastfeeding: Generally considered safe, but discuss benefits and risks.
Lifestyle & Diet
- Avoid grapefruit juice, which can increase drug levels.
- Alcohol does not affect Zofran’s efficacy, but limit intake if you feel dizzy.
Precautions and Warnings
- Use caution if you have a prolonged QT interval or are on other QT-prolonging drugs.
- Notify your provider of any history of heart rhythm disorders.
- Do not use if you are allergic to ondansetron or any tablet ingredients.
Drug Interactions
| Drug Class | Interaction Risk | Recommended Action |
|---|---|---|
| Antifungal azoles (e.g., fluconazole) | Increases Zofran levels | Monitor ECG, consider dose reduction |
| Certain antibiotics (e.g., erythromycin) | QT prolongation | Check ECG, avoid combined use if possible |
| Apomorphine | Severe hypotension | Contraindicated; do not co-administer |
Potential Side Effects
Common Side Effects
- Headache
- Constipation
- Fatigue
Less Common Side Effects
- Dizziness
- Diarrhoea
- Fever
Serious Side Effects
- Irregular heartbeat or palpitations - seek medical help immediately.
- Severe allergic reaction (rash, swelling, difficulty breathing) - call emergency services.
Who Should Avoid This Medication?
- Patients with known hypersensitivity to ondansetron or any tablet component.
- Individuals with a history of severe arrhythmias not well-controlled.
- Those currently taking apomorphine.
Storage Instructions
- Keep tablets below 25 °C, away from moisture and direct sunlight.
- Store in the original container tightly closed.
- Keep out of reach of children.
Zofran Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Granisetron | 5-HT₃ antagonist | Longer half-life, injectable form |
| Palonosetron | 5-HT₃ antagonist | Monthly dosing for chemotherapy |
| Metoclopramide | Dopamine antagonist | May cause drowsiness, less specific for chemotherapy-induced nausea |
Frequently Asked Questions
How long does Zofran start working?
Zofran usually begins to reduce nausea within 30 minutes after ingestion.
Can I take Zofran on an empty stomach?
Yes, the tablet may be taken with or without food.
Is Zofran safe for patients with liver disease?
Dose adjustment is often needed for moderate to severe hepatic impairment; discuss with your clinician.
Will Zofran cause drowsiness?
Drowsiness is uncommon, but if it occurs, avoid driving or operating heavy machinery.
Can I drink coffee while on Zofran?
Moderate coffee intake is permissible; excessive caffeine may increase heart rate, which should be monitored.
What should I do if I experience a rapid heartbeat?
Stop the medication and seek urgent medical attention, as this may signal a serious cardiac reaction.
Is Zofran covered by Singapore’s MediShield Life?
Coverage depends on individual subsidy eligibility; check with your health plan provider.
Can I use Zofran for motion sickness?
It is not the first-line treatment for motion sickness; other agents are typically preferred.
Glossary
- 5-HT₃ receptor antagonist: A drug that blocks serotonin receptors involved in triggering vomiting.
- QT interval: A measurement on an electrocardiogram that reflects heart rhythm; prolongation can increase Arrhythmia risk.
- Bioavailability: The proportion of a drug that enters circulation when introduced into the body and can have an active effect.
Disclaimer
The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses should be discussed with a qualified healthcare provider. Readers are responsible for ensuring the medication is appropriate for their condition and for following the usage guidelines of our online pharmacy platform. Always consult a healthcare professional before starting or changing any medication regimen.
Zofran Properties
- Original Manufacturer: GlaxoSmithKline
- Clinical use: Used to prevent nausea and vomiting, particularly in chemotherapy or post-surgery.
- Spectrum of activity: Acts on the serotonin 5-HT3 receptors in the brain to prevent nausea.
- Mechanism of action: Blocks serotonin receptors in the chemoreceptor trigger zone and gastrointestinal tract.
- Classification: 5-HT3 receptor antagonist
- Recommended Dosage: 4-8 mg orally every 8-12 hours, adjusted based on the condition.
- Basic Side Effects: Headache, Dizziness, Constipation
- Moderate Side Effects: Dry mouth, Fatigue
- Serious Side Effects: Arrhythmias, Serotonin syndrome
Zofran Drug Class
Zofran Connected Conditions
How to order Zofran from our Online Pharmacy
To order Zofran | Ondansetron on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Zofran / Ondansetron pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Zofran pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Absolute lifesaver for chemo nausea, seriously. The 8mg pill kills the feeling dead in its tracks. BUT, I'm talking serious constipation. Like, need a whole bottle of Senokot serious. Lifelong battle now. Try taking it with a huge glass of prune juice, it helps a bit. Don't wait for the symptoms to hit; time it proactively.
Just started Ondansetron 4mg for really bad morning sickness. The vomiting stopped immediately, which is amazing. Feels like I can actually keep food down now. But my head feels heavy, like a constant dull throb. It's not a full headache, just super foggy. Also, the dry mouth is insane. Keep a huge water bottle next to you, trust me. New to this, hoping the head fog goes away soon.
I've been on 4mg for years for IBS-related episodes. It works perfectly, but you NEED to split the tablet. Half of a 4mg (2mg) is usually enough for mild nausea, and it cuts the headache risk by half. If you take the full pill, save the day for when you don't need to drive. It also causes a weird metallic taste if I take it without food. Always keep this stash handy; it's reliable.
Works for the stomach issues, absolutely. Used it after a bad food poisoning episode in Bali. Within 30 minutes, the heaving stopped. The drawback? The next day, I felt completely off. Like my heartbeat was skipping. It was probably just anxiety, but it felt rough. Protip: Don't chew it, obviously, and make sure you drink electrolytes afterwards because the blockage can dehydrate you faster.
I use Zofran for severe motion sickness when flying, but recently tried it for a migraine-induced nausea. Didn't work so well for the migraine, honestly. Took the edge off the sickness but barely touched the head pain. The big side effect for me is the QT prolongation fear. I keep my caffeine intake low on pill days just to be extra careful. Complex drug, great for vomit, iffy for headache synergy.
Been using the 8mg tablets off and on for post-surgery recovery. Massive help. My trick: if I feel a little dizzy after taking it, I immediately lie down for 15 minutes. It seems to stabilize things. My bowel movements are practically non-existent for 48 hours later, though. You have to balance the relief vs the total blockage. Long-term user, accept the trade-off.
New user here. Took the 4mg pill based on my doctor's advice for post-viral nausea. It worked, but I felt a weird tightening in my chest, maybe palpitations? It freaked me out enough that I only took it once. The nausea relief was instant, but the anxiety from the side effect wasn't worth it. Is this common? Should I try splitting it next time? Not sure if I'll risk it again.
This is the gold standard for my cyclic vomiting syndrome. I know exactly when to take the 8mg-at the first sign of that "aura." Stops the cycle from turning catastrophic. However, it completely wipes out my appetite for the next 12 hours *after* it solves the sickness. Also, don't take it right before bed; it messes with my sleep pattern badly. Take it early in the evening.