Buy Xeloda
xeloda
$263.70
- Active ingredient: Capecitabine
- Category: Oncology Support
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Xeloda (Capecitabine) 500mg tablets are available to order from our trusted Singapore pharmacy with discreet packaging. This oral chemotherapy medication converts to 5-fluorouracil in the body, effectively treating breast cancer and colorectal cancer. Xeloda works by interfering with cancer cell DNA production, preventing tumor growth and spread while minimizing damage to healthy cells. The convenient oral administration makes it suitable for patients requiring cancer treatment who prefer home-based therapy over intravenous chemotherapy, offering effective tumor control with manageable side effects.
Table of contents
- Xeloda (Capecitabine) Buyer and Patient Handbook in Singapore
- What is Xeloda?
- Who Should Use Xeloda?
- How Does It Work?
- Why Choose Xeloda?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Xeloda Alternatives
- Frequently Asked Questions
- How long does it take for Xeloda to start working?
- Can I drink coffee while on Xeloda?
- Is it safe to take Xeloda with over-the-counter pain relievers?
- What should I do if I develop hand-foot syndrome?
- Do I need to adjust the dose if I miss a dialysis session?
- Can I travel abroad while taking Xeloda?
- Will Xeloda affect my blood sugar levels?
- How often will my blood tests be done?
- Glossary
- Disclaimer
- Xeloda Properties
- Xeloda Drug Class
- Xeloda Connected Conditions
- How to purchase Xeloda on our Website
- Reviews
- Write your review
Xeloda (Capecitabine) Buyer and Patient Handbook in Singapore
What is Xeloda?
Xeloda is an oral chemotherapy pill belonging to the antimetabolite class, used to treat various solid tumours such as colorectal and Breast Cancer. It works by interfering with Cancer cells’ DNA synthesis. In Singapore, it is approved by the Health Sciences Authority (HSA) and carries the same regulatory standards as FDA-approved products. The medication is supplied as a film-coated tablet.
Who Should Use Xeloda?
- Adults diagnosed with metastatic colorectal, gastric, or breast cancer.
- Patients whose oncologist determines that an oral fluoropyrimidine is appropriate.
- Individuals with adequate liver, kidney, and bone-marrow function to tolerate chemotherapy.
How Does It Work?
Xeloda is a pro-drug that is converted in the body to 5-fluorouracil (5-FU). 5-FU mimics the nucleotide uracil, causing cancer cells to incorporate it into their DNA during replication, which halts cell division and triggers cell death. Think of it as inserting a faulty piece into a machine that makes it stop working. While effective against tumours, it can also affect normal rapidly dividing cells, so monitoring for side effects is essential.
Why Choose Xeloda?
- Convenient oral dosing eliminates the need for frequent clinic-based infusions.
- Proven efficacy in large clinical trials for colorectal, gastric, and breast cancers.
- Cost-effective compared with intravenous regimens, especially when generic equivalents are available. Off-label uses exist (e.g., certain head-and-neck cancers) but should only be considered after professional consultation.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
The usual prescribed amount is 500 mg taken twice daily (total 100 mg per day) on a two-weeks-on, one-week-off schedule. Adjustments may be required based on kidney or liver function.
How to Take
- Swallow the tablet whole with a full glass of water.
- Take doses at the same times each day (e.g., morning and evening) to maintain steady blood levels.
- Do not crush, chew, or split the tablet unless specifically instructed.
Missed Dose
If you remember the missed dose within 8 hours, take it immediately. If it’s been longer, skip the dose and resume the next scheduled dose-do not double-dose.
Overdose
If an overdose is suspected, seek emergency medical care right away. Bring the medication packaging with you for reference.
Special Populations
- Elderly: Start at a lower dose and monitor blood counts closely.
- Renal or hepatic impairment: Dose reductions are often required; a physician will adjust accordingly.
- Pregnancy & breastfeeding: Contra-indicated due to potential harm to the fetus or infant.
Lifestyle & Diet
- Avoid grapefruit juice as it may increase Xeloda levels.
- Stay hydrated to help kidney function.
- Limit alcohol; excessive intake can worsen liver toxicity.
- Maintain a balanced diet rich in protein to support bone marrow health.
Precautions and Warnings
- Monitor complete blood counts regularly; low neutrophils increase infection risk.
- Watch for signs of hand-foot syndrome (redness, swelling, Pain on palms/soles).
- Report any severe Nausea, Vomiting, or diarrhoea promptly.
- Use effective contraception; Xeloda is teratogenic.
Drug Interactions
| Drug/Class | Risk | Action |
|---|---|---|
| Anticoagulants (e.g., warfarin) | ↑ Bleeding risk | Monitor INR frequently |
| CYP2C9 inhibitors (e.g., fluconazole) | ↑ Xeloda plasma levels | Dose adjustment may be needed |
| Antacids containing magnesium/aluminum | ↓ Absorption | Separate administration by ≥2 h |
Potential Side Effects
Common Side Effects
- Nausea, vomiting
- Diarrhoea
- Fatigue
- Hand-foot syndrome ( redness, swelling of palms/soles)
Less Common Side Effects
- Mild hair thinning
- Low white-blood-cell count (leukopenia)
- Elevated liver enzymes
Serious Side Effects
- Severe neutropenia (infection risk) - seek medical help
- Severe diarrhoea with dehydration - seek medical help
- Cardiac events (rare) - seek medical help
Who Should Avoid This Medication?
- Patients with known hypersensitivity to capecitabine or its excipients.
- Individuals with severe renal or hepatic impairment not amenable to dose reduction.
- Pregnant or nursing women.
Storage Instructions
- Store at room temperature (15-30 °C), away from direct sunlight.
- Keep the bottle tightly closed to protect from moisture.
- Keep out of reach of children and pets.
Xeloda Alternatives
| Name | Class | Key Difference |
|---|---|---|
| 5-Fluorouracil (IV) | Antimetabolite | Intravenous administration only |
| S-1 (Taiho) | Fluoropyrimidine | Oral formulation with different enzyme modulation |
| Trifluridine/Tipiracil (Lonsurf) | Nucleoside analogue | Used after failure of standard fluoropyrimidines |
Frequently Asked Questions
How long does it take for Xeloda to start working?
Therapeutic effects may become evident after 2-3 weeks of treatment, but tumour response is usually assessed after several cycles using imaging.
Can I drink coffee while on Xeloda?
Moderate coffee intake (1-2 cups per day) is generally safe, but avoid excessive caffeine as it may aggravate dehydration.
Is it safe to take Xeloda with over-the-counter pain relievers?
Acetaminophen is usually fine, but avoid NSAIDs (e.g., ibuprofen) unless advised, because they can increase bleeding risk.
What should I do if I develop hand-foot syndrome?
Apply moisturising creams, avoid friction or heat, and inform your healthcare provider-dose reduction may be needed.
Do I need to adjust the dose if I miss a dialysis session?
Xeloda dosing is not directly linked to dialysis; however, discuss any missed sessions with your doctor for individualized advice.
Can I travel abroad while taking Xeloda?
Yes, but keep the medication in its original packaging, carry a copy of the prescription (for reference only), and store it at room temperature.
Will Xeloda affect my blood sugar levels?
It does not directly alter glucose metabolism, but steroid co-medication may. Monitor blood sugar if you have Diabetes.
How often will my blood tests be done?
Typically before each treatment cycle (every 2-3 weeks) to check blood counts, liver, and kidney function.
Glossary
- Antimetabolite: A drug that mimics normal cellular building blocks, disrupting DNA synthesis.
- Hand-foot syndrome: Redness, swelling, and pain on the palms and soles caused by certain chemotherapy agents.
- Pro-drug: An inactive compound that is converted in the body to its active form.
Disclaimer
This guide provides general information about Xeloda (capecitabine) and is not a substitute for professional medical advice. Off-label uses should only be considered after thorough discussion with a qualified healthcare provider. Readers are responsible for verifying the suitability of this medication for their personal health circumstances. Our platform offers educational resources and facilitates access to licensed pharmacies in Singapore; it does not dispense prescriptions or replace clinical consultation. Always consult a qualified healthcare professional before starting or changing any treatment.
Xeloda Properties
- Original Manufacturer: Roche
- Clinical use: Used to treat breast, colorectal, and gastric cancers.
- Spectrum of activity: Oral chemotherapeutic agent.
- Mechanism of action: Converts to 5-fluorouracil (5-FU) in the body, which interferes with DNA synthesis.
- Classification: Oral fluoropyrimidine carbamate
- Recommended Dosage: Dose varies based on condition and patient response.
- Basic Side Effects: Nausea, Diarrhea, Fatigue
- Moderate Side Effects: Mouth sores, Skin rash, Hand-foot syndrome
- Serious Side Effects: Bone marrow suppression, Liver toxicity
Xeloda Drug Class
Xeloda Connected Conditions
How to purchase Xeloda on our Website
To purchase Xeloda | Capecitabine on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Xeloda / Capecitabine pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Xeloda pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Just finished my first cycle of Capecitabine 500mg. The Hand-Foot Syndrome is 100% real. My soles are burning, walking feels like stepping on hot coals. My oncologist said to expect it but gave no real solution. User hack: Get a thick urea cream, put it on at night, and wear cotton socks. It helps manage the cracking, but the redness is constant. Lost my appetite too.
Been on Xeloda for eight months now. It controls the metastasis, which is the main win, but the diarrhea schedule is brutal. I literally schedule every outing around the restroom availability. Tip I wish I knew sooner: Take the 500mg pills exactly 12 hours apart, and *always* with a hefty meal. Not just a snack, a proper meal. That seems to buffer the GI upset marginally.
I'm only three weeks in. The fatigue hits like a wall around 2 PM, even if I get a full night's sleep. I try to split the dose 12/12, but sometimes I forget and take it closer to 10 hours apart, and the nausea comes back immediately. The good news is my blood markers are improving quickly. I'm just terrified of the fatigue worsening when the dosage increases next month.
This drug is effective for keeping my tumor stable, but it destroys your ability to taste. Everything tastes metallic, like licking a rusty spoon. It's hard to eat enough calories. User hack: Eat spicy food or strongly flavored fruit like mangoes and durian. The intense flavor cuts through that metallic taste slightly, helping me keep weight on. Worth dealing with the HFS pain.
My fingers and toes looked like something from a horror movie after the second cycle. Peeling, cracked skin, and deep redness. Stopped taking Xeloda for a week to let them recover, which worried the doctor, but honestly, I couldn't function. Pro tip: High-dose B6 supplements (Pyridoxine) helps prevent the worst nerve pain symptoms, or at least dulls them significantly. Check with your team first, though.
The mouth sores are the unexpected killer. Swallowing water is painful sometimes. It's frustrating because the drug is doing its job against the main problem, but side effects pile up. I found that mixing baking soda and salt in warm water for rinsing 3-4 times a day prevents them from getting completely out of control. Don't skip the rinse, even if you are tired.
Three years on this. My hair thinned noticeably-it didn't fall out completely, but it's super brittle now. The big complex issue is the constant eye tearing; I feel like I have perpetual allergies. It affects my driving. The trade-off is huge, though. My scans are good, and I have minimal fatigue now compared to the first six months. The body adapts, but the eyes don't.
Started two months ago. My dosage is slightly lower than standard because I couldn't cope with the initial GI distress at 1000mg BID. It's working on the tumor but causing strange neurological symptoms-like brief dizziness when standing up too fast. User hack: Drink massive amounts of water, especially electrolyte drinks (Pocari Sweat works great). Dehydration makes all the symptoms ten times worse.