Hydrea

Buy Hydrea
hydrea

$86.40

  • Active ingredient: Hydroxyurea
  • Category: Oncology Support
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Hydrea (Hydroxyurea) 500mg capsules are available for order with delivery throughout Singapore. This medication works by slowing the growth of cancer cells or abnormal blood cells in the bone marrow, making it useful for treating certain types of cancer and blood disorders. It is an important therapy for patients managing conditions like chronic myeloid leukemia, sickle cell anemia, or polycythemia vera.

Table of contents

Hydrea (Hydroxyurea) Buyer and Patient Handbook in Singapore

What is Hydrea?

Hydrea is the brand name for hydroxyurea, an antimetabolite used as a cancer-support medication. It belongs to the antineoplastic drug class and is indicated mainly for sickle-cell disease and certain leukemias. In Singapore, the product is approved by the Health Sciences Authority (HSA) and is supplied as oral pills.

Who Should Use Hydrea?

  • Adults diagnosed with sickle-cell disease needing to reduce painful crises.
  • Patients with Chronic Myelogenous Leukemia (CML) or other myeloproliferative disorders as advised by a specialist.
  • Individuals for whom disease-modifying therapy is part of a long-term management plan.

How Does It Work?

Hydroxyurea interferes with DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which limits the production of deoxyribonucleotides needed for cell replication. The result is a reduction in rapidly dividing abnormal blood cells, while also increasing fetal hemoglobin in sickle-cell disease, which improves red-cell flexibility. Abuse potential is low, but regular monitoring is essential to avoid bone-marrow suppression.

Why Choose Hydrea?

Choosing the branded Hydrea provides assurance of consistent formulation and bioavailability, while still offering the therapeutic benefits of hydroxyurea. For patients seeking cost savings, approved generic hydroxyurea tablets are bioequivalent alternatives. Off-label uses (e.g., certain dermatologic conditions) should only be considered after specialist consultation.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • Standard adult dose: 500 mg taken orally once daily (dose may be adjusted by the treating clinician).

How to Take

  1. Swallow the tablet whole with a full glass of water.
  2. Take it at the same time each day to maintain steady blood levels.
  3. Can be taken with or without food; a light snack may reduce stomach upset.

Missed Dose

  • If you remember the dose within 12 hours, take it now.
  • If more than 12 hours have passed, skip the missed dose and resume the regular schedule. Do not double-dose.

Overdose

  • Seek immediate medical attention if symptoms such as severe Nausea, Vomiting, or bleeding occur.
  • Bring the medication packaging to aid clinicians in management.

Special Populations

  • Elderly: Start at a lower dose (e.g., 250 mg) and titrate cautiously.
  • Renal impairment: Dose reduction is recommended; monitor kidney function regularly.
  • Pregnancy & lactation: Use only if benefits outweigh risks; discuss with a specialist.

Lifestyle & Diet

  • Avoid large quantities of grapefruit juice, which can affect drug metabolism.
  • Maintain adequate hydration; aim for at least 1.5 L of fluid daily.
  • Limit alcohol intake, as it may increase bone-marrow suppression risk.

Precautions and Warnings

  • Monitor complete blood count (CBC) every 2-4 weeks during dose titration.
  • Discontinue if severe neutropenia or thrombocytopenia develops.
  • Use effective contraception; hydroxyurea is teratogenic.
  • Report any signs of infection, unusual bruising, or prolonged bleeding promptly.

Drug Interactions

Drug Class Risk Action
Antiretrovirals (e.g., zidovudine) Enhanced myelosuppression Monitor CBC closely; adjust dose
NSAIDs (ibuprofen, naproxen) ↑ bleeding risk Use lowest effective dose; monitor
Live vaccines Reduced efficacy Avoid during therapy or schedule after washout

Potential Side Effects

Common Side Effects

Less Common Side Effects

  • Skin rash
  • Elevated liver enzymes
  • Mild renal impairment

Serious Side Effects

  • Severe neutropenia (infection risk) - Call a doctor immediately
  • Significant thrombocytopenia (bleeding) - Seek urgent care
  • Pulmonary toxicity - Report new shortness of breath

Who Should Avoid This Medication?

  • Patients with known hypersensitivity to hydroxyurea or any excipients.
  • Those with severe bone-marrow failure (e.g., aplastic anemia).
  • Individuals currently receiving other myelosuppressive chemotherapy without specialist guidance.

Storage Instructions

  • Keep tablets in the original container, tightly closed.
  • Store at 20-25 °C (68-77 °F); protect from moisture and direct light.
  • Keep out of reach of children and pets.

Hydrea Alternatives

Name Class Key Difference
Generic Hydroxyurea Antimetabolite Lower cost, same active ingredient
Hydroxycarbamide Antimetabolite Alternative brand, same indication
Myleran (busulfan) Alkylating agent Used for different leukemias

Frequently Asked Questions

How long does it take for Hydrea to show benefits in sickle-cell disease?

Most patients notice a reduction in Pain crises within 3-6 months of stable dosing.

Can I take Hydrea with my regular coffee habit?

Yes, moderate coffee consumption does not affect hydroxyurea’s action.

Is it safe to drink alcohol while on Hydrea?

Small amounts are generally tolerated, but excessive alcohol can worsen bone-marrow suppression; limit intake.

What should I do if I develop a rash?

Stop the medication and contact a healthcare professional; a rash may signal an allergic reaction.

Will Hydrea affect my fertility?

Hydroxyurea can reduce sperm count and affect menstrual cycles; discuss fertility preservation with a specialist if relevant.

Can I travel internationally while on Hydrea?

Yes, but carry a copy of your medical record and ensure you have a supply for the trip duration.

My blood tests show low platelets-should I continue the drug?

Do not adjust the dose yourself; consult your clinician promptly for guidance.

Are there any over-the-counter supplements I should avoid?

Avoid high-dose folic acid or vitamin B12 without medical advice, as they may mask blood-count changes.

Glossary

  • Antimetabolite: A drug that mimics normal cellular building blocks, disrupting DNA synthesis.
  • Fetal hemoglobin: A form of hemoglobin that remains in newborns; increasing its level improves red-cell flexibility in sickle-cell disease.
  • Myelosuppression: Decreased production of blood cells by the bone marrow, leading to anemia, neutropenia, or thrombocytopenia.

Disclaimer

The information provided here is for general educational purposes only and does not substitute professional medical advice. Off-label uses should be discussed with a qualified healthcare provider. Readers are responsible for verifying the suitability of Hydrea for their own health situation. Our platform offers a convenient way to obtain licensed medicines in Singapore, but it does not prescribe or guarantee clinical outcomes. Always consult a doctor or pharmacist before initiating or changing any medication regimen.

Hydrea Properties

  • Original Manufacturer: Cephalon, Inc.
  • Clinical use: Used to treat sickle cell anemia, certain cancers, and psoriasis.
  • Spectrum of activity: Antimetabolite.
  • Mechanism of action: Inhibits DNA synthesis by interfering with ribonucleotide reductase, leading to cell death.
  • Classification: Antimetabolite
  • Recommended Dosage: Dose varies based on condition and patient response.
  • Basic Side Effects: Nausea, Fatigue, Mouth sores
  • Moderate Side Effects: Skin ulcers, Infections, Liver issues
  • Serious Side Effects: Bone marrow suppression, Cancer

Hydrea Drug Class

Antimetabolites

How to order Hydrea from our Online Pharmacy

To order Hydrea | Hydroxyurea on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Hydrea / Hydroxyurea pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Hydrea pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.74/148
Hydrea

Been on Hydrea for about 3 weeks now for my blood condition. The fatigue hit me like a truck for the first few days, honestly thought I couldn't continue. But my doctor said to push through, and it's getting a bit better now. The weirdest thing is the skin on my hands and feet is so dry and dark now, like I've been gardening without gloves. Taking it with a big meal helps a lot with the nausea.

Siti A. Kuala Lumpur, Malaysia

Hydrea is keeping my platelet count in check, which is a huge relief. But man, the mouth ulcers are no joke. I found that using a soft-bristle toothbrush and avoiding spicy food makes a big difference. Also, my hair feels thinner, which is a bummer. It's a trade-off I guess. I've learned to take it right before bed to sleep through the worst of the initial wooziness.

Maria L. Manila, Philippines

Two years on this medication. It's controlling my condition, but you have to be smart about it. I never skip my blood tests. The key hack I learned from an online group: HYDRATE like crazy. I drink 3 liters of water a day minimum, otherwise the leg cramps are unbearable. Also, always use sunscreen. My skin got super sensitive to the sun. It's a maintenance drug, not a cure.

Ahmad R. Singapore

It works, but the side effects are real. The fatigue is manageable now, but I still get these random fevers. My doctor says it's normal. I split my 500mg pill as advised to take half in the morning and half at night. Smoother that way. Biggest issue is the taste? The pill itself has this weird, chalky taste if it even slightly dissolves in your mouth. Chase it with juice, not water.

Chandra S. Denpasar, Indonesia

Been taking Hydrea for 8 months. My counts are stable, which is the main thing. You get used to the side effects. The dry skin is the most persistent issue for me. I slather on moisturizer twice a day. A tip: take it with a spoonful of yogurt. It really helps coat the stomach. Don't take it on an empty stomach, learned that the hard way.

David T. Bangkok, Thailand

This medication is a double-edged sword for me. It's essential for my blood disorder, but it's wrecked my nails. They're brittle and have these ridges. Also, I can't seem to shake off a constant, low-grade headache. I tried taking it with food, without food, different times of day... the headache stays. But stopping isn't an option. You just learn to live with it.

Anita G. Johor Bahru, Malaysia

Newbie here. One week in. The nausea was intense at first. My doctor prescribed an anti-nausea pill to take 30 mins before the Hydrea, and that was a game-saver. Also experiencing a weird metallic taste in my mouth all the time. Chewing sugar-free gum helps. Hoping these initial side effects settle down soon because the alternative is worse.

Wei J. Singapore

Five-year veteran. Hydrea gave me my life back from my condition, but it's not without cost. The most important advice: be religious with your blood monitoring. I've had to adjust my dose a few times over the years. The fatigue comes and goes in waves. I plan my most demanding tasks for the days I feel good. It's about management, not a magic bullet.

Rosa D. Cebu City, Philippines

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