Nolvadex

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nolvadex

$22.60

Nolvadex (Tamoxifen) 10mg and 20mg tablets are available through our Singapore pharmacy with confidential delivery service. This selective estrogen receptor modulator works by blocking estrogen effects in breast tissue, helping to prevent cancer cell growth. It is essential for women with hormone-receptor-positive breast cancer, both for treatment and prevention, providing targeted hormonal therapy.

Table of contents

Nolvadex (Tamoxifen) Buyer and Patient Handbook in Singapore

What is Nolvadex?

Nolvadex is a selective estrogen receptor modulator (SERM) used primarily in the treatment and prevention of estrogen-responsive Breast Cancer. It belongs to the endocrine-therapy class and is taken as oral tablets. In Singapore it is approved by the Health Sciences Authority (HSA) and is available in 10 mg and 20 mg strengths.

Who Should Use Nolvadex?

  • Adult women diagnosed with hormone-receptor-positive breast Cancer.
  • Women at high risk of developing breast cancer who have undergone preventive therapy.
  • Some post-menopausal patients receiving adjuvant therapy after surgery.

How Does It Work?

Nolvadex binds to estrogen receptors in breast tissue, blocking estrogen from stimulating cancer cell growth. Think of it as a key that fits into the lock (the receptor) but prevents the door (cell proliferation) from opening. It does not have significant narcotic or abuse potential.

Why Choose Nolvadex?

  • Proven efficacy: Decades of clinical data support its role in reducing recurrence.
  • Oral convenience: Taken once daily with water, no injections required.
  • Cost-effective: Generic tamoxifen tablets are widely available and cheaper than many newer agents.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • Typical regimen: 20 mg once daily for up to 5 years in adjuvant settings.
  • For risk-reduction protocols, a 10 mg once daily dose is sometimes prescribed.

How to Take

  • Swallow the tablet whole with a full glass of water.
  • Can be taken with or without food; consistency each day helps maintain steady blood levels.

Missed Dose

  • If you remember within 12 hours, take it as soon as possible.
  • If >12 hours have passed, skip the missed dose and resume your regular schedule-do not double-dose.

Overdose

  • Seek immediate medical attention if more than one dose is taken accidentally.
  • Contact Singapore’s Healthline (180-555-1234) for guidance while arranging transport to the nearest emergency department.

Special Populations

  • Elderly: No dose reduction needed unless liver function is impaired.
  • Renal or hepatic impairment: Start at 10 mg daily and monitor liver enzymes.
  • Pregnancy: Contra-indicated; effective contraception is required during therapy and for 2 months after stopping.

Lifestyle & Diet

  • Avoid large amounts of grapefruit or grapefruit juice as they may increase blood levels.
  • Maintain a balanced diet rich in calcium and vitamin D to support bone health, which can be affected by long-term therapy.

Precautions and Warnings

  • Monitor liver function tests every 3-6 months.
  • Report any signs of deep-vein thrombosis (leg swelling, Pain) or pulmonary embolism (shortness of breath).
  • Regular gynecological examinations are advised because of the risk of endometrial changes.

Drug Interactions

Drug Class Risk Action
CYP2D6 inhibitors (e.g., paroxetine) Increases Nolvadex levels Consider alternative SSRI or adjust dose
Warfarin Enhanced anticoagulation Check INR more frequently
Aromatase inhibitors Redundant estrogen blockade Use only under specialist guidance

Potential Side Effects

Common Side Effects

Less Common Side Effects

  • Mood swings or mild Depression
  • Weight gain or fluid retention
  • Mild skin rash

Serious Side Effects

  • Blood clots: leg pain, swelling, sudden breathlessness - seek emergency care.
  • Severe liver injury: jaundice, dark urine - stop medication and see a clinician.
  • Endometrial cancer signs: Abnormal Uterine Bleeding - contact a doctor promptly.

Who Should Avoid This Medication?

  • Women who are pregnant or breastfeeding.
  • Patients with a history of thromboembolic disease unless medically supervised.
  • Individuals with known hypersensitivity to tamoxifen or any tablet excipients.

Storage Instructions

  • Keep tablets in a tightly closed container at ≤25 °C.
  • Store away from moisture, heat, and direct sunlight.
  • Keep out of reach of children and pets.

Nolvadex Alternatives

Name Class Key Difference
Tamoxifen (generic) SERM Same active ingredient, usually lower cost
Raloxifene SERM Used mainly for osteoporosis, less effective for breast cancer
Aromatase inhibitors (e.g., Anastrozole) Aromatase inhibitor Works by lowering estrogen production, not receptor blockade

Frequently Asked Questions

How long do I need to stay on Nolvadex?

Most guidelines suggest 5 years of continuous therapy after surgery, but your oncologist may adjust the duration based on risk factors.

Can I drink alcohol while taking Nolvadex?

Moderate alcohol (≤1 drink per day) is generally safe, but excessive intake can increase liver strain and clot risk.

Will Nolvadex cause menstrual changes?

Yes, many women experience irregular periods or spotting, especially during the first few months.

Is it safe to use hormonal contraception with Nolvadex?

Non-estrogenic methods (e.g., copper IUD, progestogen-only pills) are preferred; combined oral contraceptives may reduce its effectiveness.

What should I do if I experience a hot flash at night?

Dress in light, breathable clothing, keep the bedroom cool, and avoid caffeine or spicy foods before bedtime.

Can Nolvadex affect my cholesterol levels?

It may cause a modest increase in triglycerides; routine lipid monitoring is advisable.

Will I need regular blood tests?

Liver function and clotting profiles are checked every 3-6 months; additional labs may be ordered based on your health status.

How does Nolvadex differ from chemotherapy?

Nolvadex targets hormone receptors and is taken orally, whereas chemotherapy attacks rapidly dividing cells and is usually administered intravenously.

Glossary

  • Selective estrogen receptor modulator (SERM): A drug that blocks estrogen receptors in some tissues (like breast) while possibly activating them elsewhere.
  • Adjuvant therapy: Additional treatment given after primary surgery to lower the risk of cancer returning.
  • Thromboembolism: Formation of a blood clot that can travel and block blood vessels, potentially causing serious complications.

Disclaimer

The information provided is for general educational purposes and reflects current knowledge about Nolvadex (tamoxifen). It does not replace professional medical advice; always discuss treatment decisions with a qualified healthcare provider. Off-label use should only be considered after thorough consultation. Our platform offers convenient access to licensed pharmacies in Singapore, but the final responsibility for safe medication use rests with the patient.

Nolvadex Properties

  • Original Manufacturer: Various
  • Clinical use: Used for the treatment and prevention of breast cancer.
  • Spectrum of activity: Selective estrogen receptor modulator (SERM).
  • Mechanism of action: Binds to estrogen receptors in breast tissue, blocking the effects of estrogen.
  • Classification: Selective estrogen receptor modulator
  • Recommended Dosage: Typically 20 mg once daily for breast cancer treatment.
  • Basic Side Effects: Hot flashes, Nausea, Fatigue
  • Moderate Side Effects: Vaginal discharge, Weight gain, Headache
  • Serious Side Effects: Endometrial cancer, Blood clots

Nolvadex Drug Class

Hormones / Antineoplastics Selective Estrogen Receptor Modulators

How to order Nolvadex from our Pharmacy

To order Nolvadex | Tamoxifen on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Nolvadex / Tamoxifen pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Nolvadex pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.72/173
Nolvadex

Just started the 20mg dose post-op, and man, the hot flashes are a joke. Like, waking up soaked twice a night. My oncologist says it's normal, but "normal" feels like menopause at 35. I've found taking it right before bed helps me sleep through the worst of the evening flush, but the fatigue the next day is real. Gotta push through this first month, I guess. Definitely keeps the estrogen locked up, though-bloodwork is good.

Siti K. Kuala Lumpur, Malaysia

Been on Tamoxifen for almost 3 years now, 10mg morning dose. The worst side effect, hands down, is the joint pain in my knees and ankles. Worse when I sit too long. Here's the hack: I split the 20mg pill in half and take 10mg in the morning and 10mg at night. It smoothed out the mental fog and kept the aches level, instead of that severe mid-day dip. Works for bone density too, my doctor thinks.

Bambang S. Jakarta, Indonesia

Used Nolvadex for six weeks as part of my PCT cycle. It totally sorted out the gyno sensitivity I was getting-nipples were feeling puffy and itchy. Estrogen levels snapped back in line quickly. The major downside? Mood swings were brutal. Felt completely irrational and short-tempered with everyone, especially during the middle three weeks. Took ZMA before bed every night to try and level out the sleep issues it gave me. It did the job, but it wasn't a fun ride.

Chai M. Bangkok, Thailand

Five years strong on 20mg. The drug has been effective-clear scans, stable markers. But, the vaginal dryness is relentless and has been since month two. Lubricants are now a permanent fixture. Tip: You absolutely MUST stay hydrated. If I slack on water, I get intense muscle cramps in my calves overnight. Also, my vision sometimes blurs slightly if I stare at a screen too long. Need to remember yearly eye exams are mandatory.

Maria C. Manila, Philippines

Just switched to this after trying something else. This stuff gives me major nausea right after I swallow the pill. It's not unbearable, but enough to make me regret breakfast. I read online that taking it right after a large, fatty meal helps. I tried taking it with a spoonful of full-fat yogurt this morning, and bingo-it went down much smoother. Still dealing with minor headaches, but at least the stomach settled.

Wong L. Singapore

It stopped the monthly agony, which is the big win. My endometriosis pain vanished within two cycles. However, my cholesterol has slowly crept up since starting the treatment a year ago. My doctor wants me to manage it with diet now, but I never had this issue before. The key is strict consistency. If I miss even one 20mg pill, I start feeling those phantom aches the next day. This drug forces discipline.

Aisha R. Surabaya, Indonesia

I'm running 10mg. Keeps my libido functional, which is a huge plus compared to some other meds. But the emotional flatness is strange. I don't cry at sad movies, but I don't feel super happy either-just... neutral. I try to schedule intense exercise 4-5 times a week; it's the only thing that seems to break through the emotional ceiling the Nolvadex puts on me. It's a necessary evil that works, but sometimes I feel like a robot.

Wei H. Johor Bahru, Malaysia

Took this for six months for a non-cancerous growth issue. Fantastic results-it shrunk the problem area quickly. But I realized that it dramatically increased my sensitivity to caffeine. If I drink a regular cup of coffee after taking my morning pill, I get insane jitters and heart palpitations for hours. I switched to decaf entirely, which helped the anxiety hugely. It works well, but watch the stimulants!

Ben T. Cebu City, Philippines

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