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Isotretinoin

Isotretinoin is an oral retinoid for severe acne when other appropriate treatment has not worked. It can cause serious harm during pregnancy and requires structured clinical monitoring.

Isofair

Severe Acne, Acne Conglobata

10 · 20mg

Isofair is isotretinoin 10mg and 20mg soft capsules for severe, conglobate and cystic acne, a systemic retinoid that shrinks the sebaceous glands.

From$1.17/ tabletView

Tretiva

Severe Acne, Nodulocystic Acne

5 · 10 · 20 · 30mg

Tretiva is isotretinoin from 5mg to 30mg in soft capsules for severe, nodulocystic and cystic acne, cutting sebaceous gland activity and size.

From$0.98/ tabletView

Isotroin

Acne Vulgaris, Severe Acne

10 · 20mg

Isotroin is isotretinoin 10mg and 20mg soft capsules for acne vulgaris and severe cystic acne, a retinoid that cuts sebum at its source.

From$1.17/ tabletView

Key points

  • Isotretinoin is reserved for severe or treatment-resistant acne, not routine mild acne.
  • Pregnancy prevention and testing requirements are essential because exposure during pregnancy can cause severe birth defects.
  • Major mood changes, thoughts of self-harm, severe headache with visual symptoms or a serious skin reaction needs urgent assessment.

Select a listed product and pack to order online. Supply depends on stock and destination rules; ask your doctor or pharmacist whether it suits you.

What Isotretinoin is used for

It may be prescribed for severe acne, including severe cystic acne, nodulocystic acne and acne conglobata, after assessment of previous treatment and scarring risk.

How it works

Isotretinoin reduces sebaceous-gland activity and oil production and changes how skin cells develop within pores. Improvement and adverse effects vary, so treatment is reviewed rather than selected by brand alone.

Important safety checks

Anyone who could become pregnant needs the required pregnancy-prevention plan and must not use isotretinoin during pregnancy. Liver function and blood lipids may require monitoring. Vitamin A supplements and tetracycline antibiotics need interaction review. Do not donate blood during treatment or handle treatment changes without the prescriber.

When to seek urgent care

Seek urgent help for thoughts of suicide or self-harm, marked mood or behaviour change, severe headache with nausea or visual disturbance, extensive blistering or peeling skin, facial swelling, breathing difficulty or severe abdominal pain.

Further reading

What is isotretinoin used for?

Isotretinoin is used for severe acne, including severe cystic acne, nodulocystic acne and acne conglobata, when other suitable treatment has not worked. It is not for routine mild acne.

How does isotretinoin work?

Isotretinoin cuts down the activity of the sebaceous glands and the amount of oil they make, and it changes how skin cells develop inside pores. It also shrinks the sebaceous glands and reduces bacteria, which helps calm inflammation.

Which products contain isotretinoin?

Products containing isotretinoin on SGMeds include Isofair, Tretiva and Isotroin. Compare their forms, strengths and pack sizes.

How long does isotretinoin take to work?

Some improvement can be seen in 2 to 4 weeks, and treatment usually lasts 16 to 24 weeks. How well it works and which effects you notice can differ from person to person.

What are the side effects of isotretinoin?

Common effects include a dry mouth, chapped lips, dry eyes and nosebleeds. Muscle aches, joint pain and raised liver enzymes can also happen. Depression, inflammation of the pancreas (pancreatitis) and harm to an unborn baby are serious and need urgent medical attention.

Can I take isotretinoin with other medicines?

Tetracycline antibiotics and vitamin A supplements can interact with it, so check with a doctor or pharmacist before you take them, and ask them to look at your other medicines too.

What are other names for isotretinoin?

In other countries, isotretinoin is also sold as Roaccutane. Brand names vary between countries, so compare products by their active ingredient.

How much does isotretinoin cost in Singapore?

Each product on this page shows a price for each strength and pack size in Singapore dollars, converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.

Payment and prices →

Can I order isotretinoin without a prescription?

Yes. SGMeds does not ask for a prescription to order isotretinoin: we place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.

Ordering without a prescription →

Where can I buy isotretinoin in Singapore?

You can order isotretinoin here on SGMeds: choose the product, strength and pack, then check out. We deliver to Singapore and Malaysia. Express shipping is tracked and takes up to 1 week, and Regular shipping takes up to 3 weeks.

How ordering works →

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