Buy Isotretinoin (Accutane)
Isotretinoin (Accutane)
$46.80
- Active ingredient: Isotretinoin
- Category: Hair & Skin Care
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Isotretinoin (Accutane) 10mg and 20mg capsules are available to order from our Singapore pharmacy with reliable delivery. This powerful retinoid medication works by reducing oil production in skin glands, preventing pore clogging and bacterial growth that cause severe acne. Its comprehensive action addresses the root causes of cystic and nodular acne. It is a transformative solution for adolescents and adults struggling with severe, treatment-resistant acne who seek lasting clearance.
Isotretinoin (Accutane) (Isotretinoin) Buyer and Patient Handbook in Singapore
What is Isotretinoin (Accutane)?
Isotretinoin (Accutane) is an oral retinoid medication used primarily for severe Acne that has not responded to conventional therapies. It belongs to the vitamin A-derivative class and works by reducing oil production and inflammation in the skin. The drug is approved by the Singapore Health Sciences Authority (HSA) and is available in tablet form.
Who Should Use Isotretinoin (Accutane)?
- Adults (≥ 18 years) with nodular or cystic acne resistant to topical and oral Antibiotics.
- Individuals who have tried and failed isotretinoin-compatible systemic treatments.
- Patients without pregnancy potential (see contraindications).
How Does It Work?
Isotretinoin normalises the growth and function of sebaceous glands, cutting down the amount of sebum that fuels acne-causing bacteria. Think of it as turning down the thermostat on an over-active oil heater in the skin. Because it influences cell differentiation, the drug can cause changes in other vitamin A-sensitive tissues, so monitoring is essential.
Why Choose Isotretinoin (Accutane)?
- High efficacy: Clinical studies show up to 90 % of users achieve clear or near-clear skin after a full course.
- Long-lasting results: Many patients experience lasting remission after a single treatment cycle.
- Versatility: Though marketed for acne, physicians sometimes consider it for severe Rosacea or refractory seborrhoeic dermatitis under specialist guidance.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Initial dose: 10 mg once daily.
- Typical maintenance: 20 mg once daily, adjusted to body weight and tolerance.
How to Take
- Swallow the tablet whole with a full glass of water.
- Take with food to improve absorption and reduce stomach upset.
Missed Dose
- If you remember within 12 hours, take the missed tablet.
- If more than 12 hours have passed, skip it and resume the regular schedule.
Overdose
- Seek immediate medical attention if more than 2 times the prescribed dose is taken.
- Report symptoms such as severe headache, visual changes, or Vomiting.
Special Populations
- Elderly: Start at the lower end (10 mg) and monitor liver function.
- Renal or hepatic impairment: Dose reduction may be required; regular blood tests are advised.
- Women of child-bearing potential: Must use effective contraception before, during, and for one month after treatment.
Lifestyle & Diet
- Avoid vitamin A-rich supplements unless approved by a clinician.
- Limit alcohol intake, as it can increase liver stress.
- Stay hydrated and use a non-comedogenic moisturizer to counter dryness.
Precautions and Warnings
- Pregnancy: Highly teratogenic; strict contraception is mandatory.
- Skin sensitivity: Expect dryness of lips, eyes, and skin; use moisturisers and lip balm.
- Psychiatric effects: Monitor mood changes; report persistent Depression or suicidal thoughts promptly.
Drug Interactions
| Drug Class | Risk | Action |
|---|---|---|
| Tetracyclines (e.g., doxycycline) | Increased intracranial pressure | Avoid concurrent use |
| Vitamin A supplements | Additive toxicity | Discontinue or reduce vitamin A intake |
| Oral contraceptives | May reduce efficacy | Confirm effective backup contraception |
Potential Side Effects
Common Side Effects
- Dry lips, dry skin, mild itching
- Mild nosebleeds (due to nasal mucosa dryness)
- Elevated triglycerides
Less Common Side Effects
- Joint or Muscle Pain
- Vision changes (night blindness)
- Hair thinning
Serious Side Effects
- Severe depression or suicidal thoughts → Seek immediate help
- Persistent abdominal Pain or jaundice → Contact a healthcare professional
- Severe allergic reaction (rash, swelling, breathing difficulty) → Emergency care required
Who Should Avoid This Medication?
- Pregnant or breastfeeding women
- Individuals with a known hypersensitivity to isotretinoin or any component of the tablet
- Patients with uncontrolled hyperlipidaemia or severe liver disease
Storage Instructions
- Keep tablets in the original blister pack, away from moisture.
- Store at 20 °C-25 °C (68 °F-77 °F); do not refrigerate.
- Keep out of reach of children and pets.
Isotretinoin (Accutane) Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Adapalene gel | Topical retinoid | Applied locally; less systemic exposure |
| Oral doxycycline | Antibiotic | Targets bacteria; not effective for severe nodular acne |
| Spironolactone | Hormonal agent | Useful for hormonal acne in females |
Frequently Asked Questions
How long does a typical treatment course last?
A full course usually spans 4-6 months, depending on the dose and individual response.
Can I drink coffee while taking Isotretinoin?
Yes, moderate coffee consumption does not interfere with the medication’s effectiveness.
Will I be able to work out while on Isotretinoin?
Physical activity is safe, but stay well-hydrated and protect your skin from excessive sun exposure.
Is it safe to take vitamins alongside Isotretinoin?
Only vitamin A-free supplements are recommended; consult a healthcare professional before adding any.
How soon will I see improvement in my skin?
Noticeable reduction in lesions often appears after 4-6 weeks, but full benefits may take several months.
What should I do if I develop severe dry skin?
Use a fragrance-free moisturizer several times daily and consider a gentle, non-stripping cleanser.
Can men use Isotretinoin without contraception?
Men do not need contraception for teratogenic risk, but they should avoid sharing medication and follow safety guidelines.
What are the signs of an allergic reaction?
Swelling of the face, lips, tongue, or throat, along with hives or difficulty breathing, require immediate emergency care.
Glossary
- Sebum: An oily substance produced by skin glands that can clog pores.
- Teratogenic: Capable of causing birth defects when taken during pregnancy.
- Hyperlipidaemia: Elevated levels of fats (lipids) in the blood, such as cholesterol or triglycerides.
Disclaimer
The information presented here is for educational purposes only and does not substitute professional medical advice. Off-label uses should be discussed with a qualified healthcare professional. Readers are responsible for verifying the suitability of Isotretinoin (Accutane) for their own health circumstances. Our online pharmacy platform provides convenient access to approved medications; however, we do not prescribe or dispense without appropriate clinical evaluation. Always consult a licensed practitioner before initiating or altering any treatment.
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Isotretinoin (Accutane) / Isotretinoin pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Isotretinoin (Accutane) pills are dispatched from outside Singapore due to prescriptions issued overseas.
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