Casodex

Buy Casodex
casodex

$60.50

  • Active ingredient: Bicalutamide
  • Category: Oncology Support
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Casodex (Bicalutamide) 50mg tablets are available to purchase from our Singapore pharmacy with reliable delivery. This anti-androgen medication works by blocking testosterone from binding to prostate cancer cells, slowing their growth. It is typically used in combination with other treatments for men managing advanced prostate cancer who require comprehensive hormonal therapy as part of their cancer management plan.

Table of contents

Casodex (Bicalutamide) Buyer and Patient Handbook in Singapore

What is Casodex?

Casodex is the brand name for bicalutamide, an oral anti-androgen used to treat Prostate Cancer. It belongs to the class of non-steroidal androgen receptor antagonists and is approved by the FDA, EMA, and Singapore’s Health Sciences Authority (HSA). The medication is supplied as a 50 mg tablet (pill).

Who Should Use Casodex?

  • Men diagnosed with locally advanced or metastatic prostate Cancer.
  • Patients undergoing combined androgen blockade with a luteinising hormone-releasing hormone (LHRH) agonist.
  • Individuals whose disease is hormone-sensitive and responsive to anti-androgen therapy.

How Does It Work?

Casodex blocks the androgen receptor, preventing testosterone and dihydrotestosterone from stimulating prostate cancer cells. Think of the receptor as a lock; Casodex is the key that fits into the lock and stops the real key (the hormone) from turning it on. This inhibition slows tumor growth and can improve survival.

Why Choose Casodex?

  • Proven efficacy: Supported by large clinical trials showing delayed disease progression.
  • Convenient dosing: Once-daily oral tablet eliminates the need for injections.
  • Brand consistency: Manufactured by Janssen, ensuring strict quality control, while generic bicalutamide offers a cost-effective alternative after patent expiration.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 50 mg taken orally once daily, preferably at the same time each day.

How to Take

  • Swallow the tablet whole with a glass of water.
  • Can be taken with or without food; consistent routine is recommended.

Missed Dose

  • Take the missed dose as soon as you remember, unless it is within 12 hours of the next scheduled dose.
  • In that case, skip the missed tablet and resume your regular schedule-do not double up.

Overdose

  • If you suspect an overdose, seek emergency medical care immediately.
  • Provide the amount taken and the time of ingestion to healthcare professionals.

Special Populations

  • Elderly: No dose adjustment needed, but monitor liver function closely.
  • Renal impairment: No specific adjustment, yet regular renal labs are advised.
  • Hepatic impairment: Use with caution; reduce dose to 25 mg if severe liver dysfunction (Child-Pugh C) is present.

Lifestyle & Diet

  • Avoid excessive grapefruit juice, which can increase blood levels of bicalutamide.
  • Alcohol does not directly interact, but heavy drinking may worsen liver toxicity.
  • Maintain a balanced diet and stay hydrated to support overall health.

Precautions and Warnings

  • Monitor liver enzymes regularly; elevation may signal hepatotoxicity.
  • Watch for signs of decreased testosterone such as Hot Flashes, reduced libido, or breast tenderness.
  • Rarely, interstitial lung disease has been reported-report persistent Cough or shortness of breath promptly.

Drug Interactions

Drug Class Risk Action
CYP3A4 inhibitors (e.g., ketoconazole) Increased bicalutamide levels Reduce Casodex dose; monitor liver
Warfarin Potential ↑ INR Check INR more frequently
Rifampin (CYP inducer) Decreased efficacy Consider alternative anti-androgen

Potential Side Effects

Common Side Effects

  • Hot flashes
  • Breast tenderness or enlargement
  • Nausea
  • Diarrhoea

Less Common Side Effects

Serious Side Effects

  • Severe liver injury (jaundice, dark urine) - seek medical help immediately.
  • Severe allergic reaction (rash, swelling, breathing difficulty) - call emergency services.

Who Should Avoid This Medication?

  • Patients with known hypersensitivity to bicalutamide or any tablet ingredients.
  • Individuals with severe hepatic impairment (Child-Pugh C).
  • Women and children (the drug is not indicated for these groups).

Storage Instructions

  • Store at 20 °C-25 °C (68 °F-77 °F).
  • Keep the bottle tightly closed, away from moisture and direct sunlight.
  • Keep out of reach of children and pets.

Casodex Alternatives

Name Class Key Difference
Generic bicalutamide Anti-androgen Same active ingredient, lower cost
Enzalutamide Androgen receptor inhibitor More potent, different side-effect profile
Apalutamide Androgen receptor inhibitor Used primarily for non-metastatic disease

Frequently Asked Questions

How long does it take for Casodex to start working?

Therapeutic effects usually become noticeable within 4-6 weeks of consistent daily use.

Can I drink coffee while taking Casodex?

Yes, moderate coffee consumption does not interfere with the drug’s action.

Is it safe to exercise while on Casodex?

Physical activity is encouraged; just stay hydrated and monitor for unusual fatigue.

Will Casodex affect my sexual function?

It can reduce libido and cause erectile difficulties due to lowered testosterone; discuss management options with your clinician.

Do I need regular blood tests?

Liver function tests every 3-6 months are recommended; additional labs may be ordered based on your health status.

Can I take Casodex with other prostate cancer meds?

Casodex is often combined with LHRH agonists; always confirm with your healthcare provider before adding new drugs.

What should I do if I experience severe nausea?

Try taking the tablet with food and a full glass of water; if nausea persists, contact your doctor for possible anti-emetic therapy.

Is there any risk of developing resistance to Casodex?

Tumor cells can become resistant over time; your doctor may adjust therapy or switch to another anti-androgen if disease progression occurs.

Glossary

  • Androgen receptor antagonist: A drug that blocks hormones like testosterone from activating prostate cancer cells.
  • LHRH agonist: Medication that suppresses the body’s production of testosterone, often used together with anti-androgens.
  • Hepatotoxicity: Liver damage caused by medication.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses are not discussed; consult a qualified healthcare professional for individualized guidance. Our service supplies approved medications through a licensed Singapore pharmacy; you remain responsible for ensuring the product is appropriate for your condition. Always discuss any concerns or questions with your doctor before starting or changing therapy.

Casodex Properties

  • Original Manufacturer: AstraZeneca
  • Clinical use: Used in the treatment of prostate cancer.
  • Spectrum of activity: Non-steroidal anti-androgen.
  • Mechanism of action: Blocks the effect of androgens (like testosterone) on prostate cancer cells.
  • Classification: Anti-androgen
  • Recommended Dosage: Typically 50 mg once daily.
  • Basic Side Effects: Hot flashes, Nausea, Fatigue
  • Moderate Side Effects: Breast tenderness, Diarrhea, Weight gain
  • Serious Side Effects: Liver problems, Lung issues

Casodex Drug Class

Antiandrogens Hormones / Antineoplastics

Casodex Connected Conditions

How to purchase Casodex on our Online Drugstore

To purchase Casodex | Bicalutamide on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Casodex / Bicalutamide pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Casodex pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.72/171
Casodex

Been on Casodex for about 6 months now. PSA dropped significantly, which is a huge relief. But man, the hot flashes are no joke. Feels like I'm going through menopause. My wife jokes about it, but it's disruptive, especially at night. Started taking it right before bed, seems to help a bit with the worst of the fatigue.

Wei L. Kuala Lumpur, Malaysia

Only two weeks in. Doctor said it might take time. So far, just feeling really tired and my breasts are tender. Hoping this is just the initial adjustment period. Trying to stay positive but it's tough when you feel drained all the time. Drinking lots of water, not sure if it helps.

Siti R. Singapore

Three years on this medication. It's keeping my cancer stable, so I can't complain too much. The key for me was splitting the 50mg pill in half and taking it twice a day. Reduced the nausea significantly. Also, avoid alcohol completely - even one beer makes the hot flashes ten times worse. It's a trade-off, but life goes on.

Carlos M. Manila, Philippines

It works, but the side effects are a package deal. My skin got super dry, and I lost a lot of muscle mass. On the plus side, my hair got thicker? Weird. I take it with a big meal, otherwise my stomach gets upset. Found a good moisturizer and just accepted the new normal. You get used to it after a year.

Anand S. Bangkok, Thailand

My husband has been on Casodex for 8 months. The emotional swings were hard at first - he'd get frustrated easily. We learned that taking it after dinner, with a bit of yogurt, really helped his mood and digestion. His latest tests are good, so we'll take the mood swings over the alternative any day. It's a learning curve for the whole family.

Mei L. Jakarta, Indonesia

Stopped my cancer progression, so that's the main thing. But the fatigue is real. I force myself to take a short walk every morning, even if I don't want to. It helps with energy levels. Also, the breast tenderness was embarrassing; my doc said it's normal but still. You just have to push through and focus on the good results.

David T. Singapore

Been on it for a month. PSA is down, which is great news. But the side effects hit me hard - intense nausea and dizziness for the first two weeks. Started taking it right before I sleep, and that was a game-changer. No more daytime dizziness. The nausea is still there a bit in the morning, but manageable. Hope it stays this way.

Ahmad F. Johor Bahru, Malaysia

It's effective, no doubt. But the loss of libido is significant. It's a tough pill to swallow, no pun intended. On the advice of a friend, I started lifting weights to combat the muscle loss. It helps with the fatigue and keeps my mind off the other stuff. You have to actively fight the side effects, can't just be passive.

Ramon G. Cebu, Philippines

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