Buy Zanaflex
zanaflex
$38.40
- Active ingredient: Tizanidine
- Category: Muscle Relaxers
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Zanaflex (Tizanidine) tablets are available to purchase from our Singapore pharmacy with reliable shipping. This short-acting muscle relaxant works by blocking nerve impulses that cause muscle spasms and stiffness, providing relief for conditions like multiple sclerosis and spinal cord injuries. Zanaflex acts on the central nervous system to reduce muscle tone and spasticity without weakening muscles significantly. With 2mg and 4mg dosage options, it offers flexible treatment for adults managing muscle spasticity who need effective relaxation with rapid onset of action for improved mobility and comfort.
Table of contents
- Zanaflex (Tizanidine) Buyer and Patient Handbook in Singapore
- What is Zanaflex?
- Who Should Use Zanaflex?
- How Does It Work?
- Why Choose Zanaflex?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Zanaflex Alternatives
- Frequently Asked Questions
- How long does it take for Zanaflex to start working?
- Can I take Zanaflex with my other muscle relaxants?
- Will Zanaflex affect my blood pressure?
- Is it safe to take Zanaflex while pregnant?
- Can I stop Zanaflex abruptly?
- Does Zanaflex interact with over-the-counter sleep aids?
- My muscles feel stiff again after a week-what should I do?
- Is grapefruit juice completely prohibited?
- Can I take Zanaflex if I have mild liver disease?
- Will Zanaflex cause dependence?
- Glossary
- Disclaimer
- Zanaflex Properties
- Zanaflex Drug Class
- Zanaflex Connected Conditions
- How to order Zanaflex from our Pharmacy
- Reviews
- Write your review
Zanaflex (Tizanidine) Buyer and Patient Handbook in Singapore
What is Zanaflex?
Zanaflex (Tizanidine) is a centrally-acting muscle relaxant used to treat spasticity, a condition where muscles are continuously contracted. It is approved by the U.S. FDA, EMA and Singapore’s Health Sciences Authority for use in adults with multiple-sclerosis-related or spinal-cord-injury-related muscle stiffness. The medication is supplied as oral pill tablets.
Who Should Use Zanaflex?
- Adults diagnosed with Spasticity from neurological disorders
- Patients who experience involuntary muscle tightness that limits mobility
- Individuals whose physicians have determined that a centrally-acting relaxant is appropriate
How Does It Work?
Tizanidine binds to α₂-adrenergic receptors in the spinal cord, decreasing the release of excitatory neurotransmitters that keep muscles contracted. Think of it as turning down the volume on a noisy speaker: the signal that tells the muscle to stay tight is dampened, allowing the muscle to relax. While dependence is uncommon, abrupt discontinuation after high-dose, long-term use can cause rebound Hypertension, so tapering under supervision is advised.
Why Choose Zanaflex?
The brand formulation offers consistent bioavailability and a well-characterised safety profile, which many patients and clinicians trust. Generic tizanidine tablets are also available in Singapore, providing a lower-cost alternative with the same therapeutic effect.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Initial: 2 mg taken up to three times daily.
- Usual: 4 mg per dose, not exceeding 12 mg per day. Adjustments are made based on response and tolerability.
How to Take
Swallow the tablet whole with a glass of water. It may be taken with or without food; taking it with a light snack can lessen dizziness. Avoid crushing or chewing the tablet.
Missed Dose
If you remember a missed dose and the next scheduled dose is more than 4 hours away, take it. Otherwise, skip the missed dose and resume your regular schedule-do not double-dose.
Overdose
Symptoms may include severe Drowsiness, low blood pressure, or slowed heart rate. Seek immediate medical help or call Singapore’s emergency number 995.
Special Populations
- Elderly: Start at 2 mg; monitor for excessive Sedation.
- Hepatic impairment: Reduce the dose by half; consult a healthcare professional.
- Renal dysfunction: No dose adjustment is required for mild to moderate impairment, but close monitoring is advised.
Lifestyle & Diet
- Alcohol: Use sparingly; combined depressant effects can intensify drowsiness.
- Grapefruit: Avoid grapefruit juice as it may raise tizanidine levels.
- Driving: Do not operate machinery until you know how the medication affects you.
Precautions and Warnings
- Do not use if you have uncontrolled High Blood Pressure or severe liver disease.
- Monitor blood pressure regularly during the first weeks of therapy.
- Inform your clinician of any history of heart rhythm problems.
Drug Interactions
| Drug/Class | Risk | Action |
|---|---|---|
| Ciprofloxacin | ↑ tizanidine plasma levels | Reduce Zanaflex dose by 50 % |
| Fluconazole | ↑ tizanidine plasma levels | Reduce dose; monitor for sedation |
| Antihypertensives (beta-blockers) | Additive ↓ blood pressure | Check BP; adjust antihypertensive dose |
Potential Side Effects
Common Side Effects
- Drowsiness
- Dry mouth
- Weakness
Less Common Side Effects
- Light-headedness
- Nausea
- Muscle Pain
Serious Side Effects
- Severe hypotension (very low blood pressure) - seek urgent care
- Hallucinations or vivid dreams - consult a clinician
- Liver enzyme elevation - monitor liver function tests
Who Should Avoid This Medication?
- Individuals with known hypersensitivity to tizanidine or any tablet component
- Patients with severe hepatic impairment (Child-Pugh C)
- Those taking strong CYP1A2 inhibitors unless dose is reduced
Storage Instructions
- Keep the tablets in the original blister pack until use.
- Store at room temperature (15 °C-30 °C); protect from excess moisture and heat.
- Keep out of reach of children and pets.
Zanaflex Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Baclofen | GABA-B agonist | Primarily acts on spinal reflexes |
| Cyclobenzaprine | Tricyclic derivative | More sedating; not for spasticity |
| Methocarbamol | Carbamate derivative | Less effect on tone, more on pain |
Frequently Asked Questions
How long does it take for Zanaflex to start working?
Most patients notice a reduction in muscle stiffness within 30 minutes to 2 hours after the first dose.
Can I take Zanaflex with my other muscle relaxants?
Generally avoid combining two central muscle relaxants because the risk of excessive sedation and respiratory Depression rises.
Will Zanaflex affect my blood pressure?
Yes, it can lower blood pressure, especially after the first few doses; regular monitoring is recommended.
Is it safe to take Zanaflex while pregnant?
There is insufficient data on safety during pregnancy; discuss alternatives with your healthcare provider.
Can I stop Zanaflex abruptly?
Stopping suddenly after prolonged use may cause rebound hypertension; a gradual taper is advisable.
Does Zanaflex interact with over-the-counter sleep aids?
Most OTC antihistamines increase sedation; use caution and discuss with a clinician before combining.
My muscles feel stiff again after a week-what should I do?
Consult your prescriber; the dose may need adjustment or a short drug holiday.
Is grapefruit juice completely prohibited?
Yes, grapefruit significantly raises tizanidine levels, increasing the risk of severe drowsiness.
Can I take Zanaflex if I have mild liver disease?
Mild impairment usually requires dose reduction; your clinician will determine the appropriate amount.
Will Zanaflex cause dependence?
Physical dependence is rare, but psychological reliance on the calming effect can develop; follow prescribed dosing.
Glossary
- Spasticity: Muscle stiffness or involuntary contraction caused by nervous-system damage.
- α₂-adrenergic receptor: A protein that, when activated, reduces nerve signals that cause muscle contraction.
- CYP1A2: An enzyme in the liver that metabolises many drugs, including tizanidine.
Disclaimer
The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses are not discussed; any change in therapy should be guided by a qualified healthcare professional. Our service offers convenient online access to approved medicines in Singapore, but the final decision to use any medication rests with you and your clinician.
Zanaflex Properties
- Original Manufacturer: Acorda Therapeutics
- Clinical use: Muscle relaxant
- Spectrum of activity: Central nervous system
- Mechanism of action: Acts on alpha-2 adrenergic receptors to reduce muscle tone
- Classification: Alpha-2 adrenergic agonist
- Recommended Dosage: 2-12 mg daily, divided into doses
- Basic Side Effects: Dry mouth, Drowsiness, Fatigue
- Moderate Side Effects: Hypotension, Dizziness, Insomnia
- Serious Side Effects: Liver problems, Severe hypotension, Arrhythmias
Zanaflex Drug Class
Zanaflex Connected Conditions
How to order Zanaflex from our Pharmacy
To order Zanaflex | Tizanidine on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Zanaflex / Tizanidine pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Zanaflex pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
First week on 2mg. The muscle spasms are definitely calmer, I can actually sleep through the night now, which is a massive win. But man, the morning hangover is real. I feel like I just chugged three beers. My doc said this is normal, but trying to drive to work feels dangerous. Seriously considering splitting the 2mg and taking half earlier. Need coffee, but they say coffee makes the dizzy worse. Stuck.
Been using Zanaflex 4mg for chronic neck spasms for six years. It works, period. The trick: take it with a high-fat snack, like a small yogurt or peanut butter toast. Taking it on an empty stomach makes the blood pressure drop too fast and you nearly black out. Yes, the dry mouth is insane, but Biotène helps. Don't bother trying to wake up and take another dose in the middle of the night; you'll just be groggy all day. One dose at 8 PM, that's the rule.
This fixed my severe trigeminal nerve pain better than Gabapentin ever did, especially at the 4mg dose at night. Here's the bad part: my bladder is completely messed up. I wake up constantly needing to go, and sometimes I feel like I can't fully empty it. It's a trade-off. Pain-free sleep versus bathroom marathon. I’ve started taking Magnesium Citrate hoping it balances something out, but not much luck yet. It's good for the nerves, terrible for the plumbing.
I only use the 2mg pill *as needed* for severe intermittent back spasms, maybe twice a month. It knocks the pain out fully in about 45 minutes, but the dizziness is immediate. I learned the hard way not to take it standing up. Sit down, lay down, and plan on being useless for 8 hours. Pro tip: if you need to function the next morning, take it before 7 PM. If you take it later, forget it, you'll be dragging until noon. It's heavy duty stuff.
I was prescribed 4mg Zanaflex for anxiety-related muscle tension (neck and shoulders constantly tight). Yes, it relaxes the muscles perfectly. But the side effect is extreme fatigue *and* weird mood swings. I get super irritable the next day, snapping at everyone. It's like I traded physical tension for emotional tension. Thinking about cutting the pill in half and trying 1mg doses during the day, maybe that minimizes the mood drop.
Long time user (3 years) for MS spasticity. I cycle between 2mg and 4mg depending on my day. Never, ever abruptly stop taking this; I tried once and the rebound spasms and headaches were lethal. You have to taper off slowly. Also, be careful with grapefruit juice, it supercharges the effect and makes you feel way too sedated. It works consistently, but it demands respect. Treat it like a sedative, not a simple painkiller.
New here, just started 4mg for nocturnal leg cramps that wake me up. The first night I thought I was hallucinating. I had extremely vivid, bizarre dreams. I woke up feeling rested because the cramps were gone, but the mental fog was thick until lunchtime. My coworker asked if I was sick. I need a solution for the leg pain, but if I can't perform at work, it's not worth it. If this doesn't improve after two weeks, I'm asking for something else.
I initially got Zanaflex for shoulder pain, but I found out it actually helps dramatically calm my Restless Legs Syndrome (RLS) during the day. I take a tiny 2mg dose around 4 PM. Side effects? The dry eyes are almost worse than the dry mouth sometimes. I have to carry eye drops everywhere. If you're using this at night, wear a sleep mask-the slightest bit of light seems to give me rebound headaches now. Still, better than constant jerking motions.