Buy Colchicine
colchicine
$67.80
- Active ingredient: Colchicum Autumnale
- Category: Muscle Relaxers
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Generic Colchicine (Colchicum Autumnale 0.5mg) tablets are available to purchase from our registered Singapore pharmacy with dependable shipping. Colchicine works by reducing the inflammation and pain caused by gout flares by inhibiting white blood cell activity and uric acid crystal deposition. It is an effective solution for adults managing acute gout attacks or familial Mediterranean fever, providing targeted relief from painful symptoms.
Table of contents
- Colchicine (Colchicum Autumnale) Buyer and Patient Handbook in Singapore
- What is Colchicine?
- Who Should Use Colchicine?
- How Does It Work?
- Why Choose Colchicine?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Colchicine Alternatives
- Frequently Asked Questions
- How quickly will Colchicine relieve gout pain?
- Can I take Colchicine with alcohol?
- Is it safe to use Colchicine while on a statin?
- What should I do if I develop diarrhea?
- Can I use Colchicine for chronic gout prevention?
- Why is my urine dark after taking Colchicine?
- Is dose adjustment needed for kidney disease?
- How should I store Colchicine when traveling?
- Glossary
- Disclaimer
- Colchicine Properties
- How to purchase Colchicine on our Website
- Reviews
- Write your review
Colchicine (Colchicum Autumnale) Buyer and Patient Handbook in Singapore
What is Colchicine?
Colchicine (Colchicum Autumnale) is a muscle relaxant used primarily to treat acute Gout flares and Familial Mediterranean Fever. It belongs to the alkaloid class of anti-inflammatory agents. In Singapore, it is approved by the Health Sciences Authority (HSA) and available as a .5 mg oral tablet.
Who Should Use Colchicine?
- Adults diagnosed with gout attacks.
- Patients with confirmed familial Mediterranean fever.
- Individuals who can tolerate oral tablets and have no severe kidney or liver impairment.
How Does It Work?
Colchicine stops inflammatory cells from migrating to the joint, reducing swelling and Pain. Think of it as a traffic officer that redirects immune-cell “vehicles” away from the affected area. It does not affect the underlying uric acid level, so lifestyle measures remain important.
Why Choose Colchicine?
- Rapid pain relief within 12-24 hours for gout flares.
- Single-tablet regimen simplifies adherence.
- Generic version offers cost savings without compromising efficacy. Off-label uses (e.g., pericarditis) should only be considered after professional consultation.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Standard acute gout: .5 mg once, then .5 mg after 1 hour (max 1.5 mg in 24 h).
- Familial Mediterranean fever: .5 mg twice daily (adjust for renal function).
How to Take
- Swallow tablet whole with a full glass of water.
- Can be taken with or without food; taking with food may reduce stomach upset.
Missed Dose
- If you remember within 2 hours, take the missed tablet.
- If more than 2 hours have passed, skip it and resume regular schedule.
Overdose
- Call emergency services (995) immediately.
- Monitor for severe Nausea, Vomiting, or diarrhea; seek medical attention promptly.
Special Populations
- Elderly: Start with .5 mg once daily; monitor blood counts.
- Renal impairment: Reduce total daily dose to .5 mg.
- Pregnancy & breastfeeding: Use only if clearly needed; consult a clinician.
Lifestyle & Diet
- Avoid excessive alcohol during an acute flare.
- No specific food interactions, but high-purine meals may trigger gout attacks.
Precautions and Warnings
- Monitor for signs of bone marrow suppression (unusual bruising, Fatigue).
- Use caution if you have liver disease or are taking CYP3A4 inhibitors.
- Do not combine with other colchicine-containing products to prevent toxicity.
Drug Interactions
| Drug Class | Risk | Action |
|---|---|---|
| CYP3A4 inhibitors (e.g., clarithromycin) | ↑ colchicine levels | Reduce dose or avoid |
| Statins (e.g., simvastatin) | Myopathy | Monitor muscle symptoms |
| Digoxin | ↑ toxicity | Check serum levels |
Potential Side Effects
Common Side Effects
- Diarrhea
- Nausea
- Abdominal pain
Less Common Side Effects
- Muscle weakness
- Rash
- Elevated liver enzymes
Serious Side Effects
- Severe neutropenia (infection risk) - seek medical help
- Toxic epidermal necrolysis - call emergency services
- Acute kidney injury - stop medication and get urgent care
Who Should Avoid This Medication?
- Individuals with known hypersensitivity to colchicine.
- Patients with severe renal or hepatic failure.
- Concurrent use of strong CYP3A4 inhibitors without dose adjustment.
Storage Instructions
- Keep tablets in original container, tightly closed.
- Store at 20-25 °C (68-77 °F); protect from moisture and light.
- Keep out of reach of children.
Colchicine Alternatives
| Name | Class | Key Difference |
|---|---|---|
| NSAIDs (e.g., indomethacin) | Anti-inflammatory | Faster onset, GI risk |
| Corticosteroids (e.g., prednisolone) | Steroid | Useful when NSAIDs contraindicated |
| IL-1 inhibitors (e.g., anakinra) | Biologic | For refractory gout or FMF |
Frequently Asked Questions
How quickly will Colchicine relieve gout pain?
Most patients feel relief within 12-24 hours after the first dose.
Can I take Colchicine with alcohol?
Moderate alcohol can worsen gout; limit intake during an attack.
Is it safe to use Colchicine while on a statin?
Yes, but monitor for muscle pain; inform your clinician of both medications.
What should I do if I develop diarrhea?
Stay hydrated and contact a healthcare professional if diarrhea persists >2 days.
Can I use Colchicine for chronic gout prevention?
Long-term low-dose therapy is an option; discuss dosing with your clinician.
Why is my urine dark after taking Colchicine?
Rarely, colchicine can cause pigment changes; report any unusual discoloration.
Is dose adjustment needed for kidney disease?
Yes, reduce the total daily dose; patients with severe impairment should avoid use.
How should I store Colchicine when traveling?
Keep the tablet container sealed, avoid extreme heat, and carry it in hand luggage.
Glossary
- Alkaloid: Naturally occurring chemical compound with pharmacologic activity.
- CYP3A4: Liver enzyme that metabolizes many drugs; inhibitors can raise drug levels.
- Neutropenia: Low count of a type of white blood cell, increasing infection risk.
Disclaimer
The information provided is for general educational purposes only and does not replace professional medical advice. Off-label uses require clinician guidance. Our online pharmacy platform offers convenient access to approved medicines, but the final decision to use any medication rests with the individual. Always consult a qualified healthcare professional before starting or changing any treatment.
Colchicine Properties
- Original Manufacturer: Various
- Clinical use: Anti-gout agent
- Spectrum of activity: Anti-inflammatory
- Mechanism of action: Inhibits microtubule formation to reduce inflammation
- Classification: Tubulin inhibitor
- Recommended Dosage: 0.6-1.8 mg daily, divided into doses
- Basic Side Effects: Nausea, Diarrhea, Abdominal pain
- Moderate Side Effects: Vomiting, Muscle pain, Rash
- Serious Side Effects: Liver problems, Kidney problems, Bone marrow suppression
How to purchase Colchicine on our Website
To purchase Colchicine | Colchicum Autumnale on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Colchicine / Colchicum-autumnale pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Colchicine pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
First gout attack last week, doc gave me this. Took the first pill and felt nothing for hours, then the stomach cramps hit. By the next morning though, the swelling in my toe went down a bit. It's not instant relief, you have to wait it out. My advice: drink tons of water, the cramping is no joke. I'm sticking with it for now.
Was so scared to start because everyone talks about the side effects. My rheumatologist said take 2 pills at the first sign of a flare, then one an hour later. That seems like a lot! I only took one and my joint pain started easing. But yeah, got hit with diarrhea the next day. Kind of a trade-off, pain or stomach issues. Still figuring it out.
Been on colchicine for 3 years now for gout prevention. The key is to not wait. The minute I feel that tiny twinge in my big toe, I take one pill with a full glass of milk. Milk helps with the stomach, trust me. If I wait even a few hours, it's too late and I need a bigger dose, which means worse side effects. It's kept me mostly flare-free.
This pill is a lifesaver for stopping a full-blown gout attack. But long-term, even the low 0.5mg dose makes my hair feel thinner. I mentioned it to my doctor and he said it's rare but possible. So now I only use it as a rescue med, not daily. I keep a strip in my wallet at all times. For daily prevention, I stick to Allopurinol.
Absolute magic for my pericarditis. Stops the chest pain within a day. The trick I learned from an old-timer: take it right after a solid meal, never on an empty stomach. If I forget and take it empty, I pay for it with nausea. Also, cut out grapefruit juice completely, it messes with the medication. Small price to pay for being able to breathe properly.
It lets me run again, which is everything. But you can't cheat. If I have a big seafood dinner or drink red wine, I know I'm playing with fire. I take one pill preemptively sometimes, but it's a fine line between prevention and side effects. The stomach stuff is manageable if you eat clean with it. It's a tool, not a cure.
Stops the gout pain in my knee brilliantly. But after a 3-day course, I get this weird muscle weakness in my legs for a week. It's like my thighs are made of jelly. Doctor says it's myopathy, a known side effect. So it fixes one problem and gives me another. I only use it for severe flares now, when I can't walk at all.
My rheumy prescribed this for my Behçet's disease mouth ulcers. Didn't do much for that, honestly. But surprisingly, it completely eliminated the recurring pain in my ankles. So I keep taking it just for that benefit. The diarrhea was brutal at first, but my body got used to it after a month. Weird how medicines work differently for everyone.