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Maxalt (Rizatriptan) Buyer and Patient Handbook in Singapore

What is Maxalt?

Maxalt is a tablet-form triptan medication used to treat acute Migraine attacks. It belongs to the class of selective serotonin 5-HT₁B/1D receptor agonists and is approved by the FDA, EMA and Singapore’s Health Sciences Authority. The medication is available in 5 mg and 10 mg tablets.

Who Should Use Maxalt?

• Adults experiencing moderate to severe migraine with or without aura.
• Individuals who need rapid relief of migraine-related headache, Nausea or light sensitivity.
• Patients who have tried over-the-counter analgesics without adequate control.

How Does It Work?

Rizatriptan binds to 5-HT₁B/1D receptors on cranial blood vessels, causing them to narrow and reducing the release of inflammatory substances. This action stops the migraine cascade, easing Pain and associated symptoms. Do not use if you have a history of cardiovascular disease because constricting blood vessels can be hazardous.

Why Choose Maxalt?

The brand formulation provides consistent absorption, delivering relief within about half an hour for many users. Generic versions contain the same active ingredient and are bioequivalent, offering a lower-cost option. Off-label uses (e.g., Cluster Headaches) should only be considered after professional guidance.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 5 mg tablet: single dose for mild attacks.
• 10 mg tablet: single dose for moderate to severe attacks. Do not exceed 30 mg in a 24-hour period.

How to Take

Swallow the tablet whole with a glass of water; it may be taken with or without food. If the migraine returns, a second dose can be taken after at least 2 hours, provided the total daily limit is not exceeded.

Missed Dose

If you forget a dose and the migraine is still present, take the tablet as soon as you remember, provided you have not reached the 30 mg daily maximum. Do not double the dose.

Overdose

Seek immediate medical attention if you suspect an overdose (e.g., taking more than 30 mg in 24 hours). Overdose symptoms may include chest pain, tightness or severe dizziness.

Special Populations

• Elderly: start with the 5 mg dose; monitor for cardiovascular side effects.
• Renal or hepatic impairment: dosage adjustment may be required; consult a healthcare professional.
• Pregnancy & lactation: only use if the benefit clearly outweighs the risk.

Lifestyle & Diet

Avoid grapefruit juice within 24 hours of taking Maxalt, as it can increase drug levels. Alcohol does not interact directly but may worsen migraine symptoms; consume in moderation.

Precautions and Warnings

• Do not use if you have uncontrolled Hypertension, ischemic heart disease, stroke, or peripheral vascular disease.
• Use cautiously in patients with risk factors for Arrhythmia.
• Discontinue if you develop chest pain, palpitations, or severe shortness of breath during treatment.

Drug Interactions

Potential Side Effects

Common Side Effects

• Tingling or numbness in fingers or toes
• Dry mouth
• Dizziness

Less Common Side Effects

• Flushing
• Fatigue
• Nasal congestion

Serious Side Effects

• Chest pain or pressure (possible Heart Attack) - seek emergency care
• Sudden, severe headache or visual changes - consult a doctor
• Allergic reaction (rash, swelling, difficulty breathing) - stop medication and seek help

Who Should Avoid This Medication?

• Patients with known hypersensitivity to rizatriptan or any tablet excipients.
• Individuals with a history of coronary artery disease, uncontrolled hypertension, or severe cerebrovascular disorders.
• Those who have taken an ergot medication within the past 24 hours.

Storage Instructions

• Keep at room temperature (15-30 °C), away from moisture and direct sunlight.
• Store out of reach of children and pets.
• Do not refrigerate or freeze.

Maxalt Alternatives

Frequently Asked Questions

How quickly can I expect relief after taking Maxalt?

Most people feel relief within 30-60 minutes, though the exact time varies with migraine severity.

Can I take Maxalt if I have mild heart disease?

Only if your doctor has confirmed that the benefits outweigh the cardiovascular risk.

Is it safe to combine Maxalt with my daily aspirin?

Aspirin does not interact directly, but discuss all cardiovascular medications with a healthcare professional.

What should I do if the migraine returns after the first dose?

You may take a second dose after 2 hours, staying within the 30 mg daily limit.

Can I use Maxalt for tension-type headaches?

No; it is specifically indicated for migraine attacks.

Will alcohol affect the effectiveness of Maxalt?

Alcohol does not reduce effectiveness but can trigger or worsen migraine symptoms.

Is there a risk of developing medication overuse headache?

Using triptans more than 10 days per month can lead to rebound headaches; limit use accordingly.

How should I store Maxalt when traveling abroad?

Keep the tablets in a cool, dry place inside your carry-on luggage, away from extreme temperatures.

Glossary

• Triptan: A class of drugs that constrict dilated blood vessels in the brain, relieving migraine pain.
• Serotonin 5-HT₁B/1D receptor: Protein sites that, when activated, narrow cranial vessels and block pain pathways.
• Bioequivalent: Two products that deliver the same amount of active ingredient into the bloodstream at the same rate.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses require a qualified healthcare provider’s evaluation. Our online pharmacy supplies medications under the regulations of Singapore’s Health Sciences Authority; users are responsible for ensuring safe and appropriate use. Always consult a qualified healthcare professional before starting, stopping, or changing any medication regimen.