Buy Prometrium
prometrium
$87.00
- Active ingredient: Progesterone
- Category: Women's Health
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Prometrium (Progesterone) 100mg and 200mg capsules are available to order from our Singapore pharmacy with reliable delivery. This natural progesterone hormone works by supporting the uterine lining and balancing estrogen effects throughout the menstrual cycle. It serves as an essential treatment for women managing hormonal imbalances, supporting fertility treatments, or experiencing menopausal symptoms who require natural hormone supplementation.
Prometrium (Progesterone) Buyer and Patient Handbook in Singapore
What is Prometrium?
Prometrium is a synthetic progesterone pill used in women’s health to support the luteal phase and manage hormone-related conditions. It belongs to the progestogen class and is approved by the Health Sciences Authority (HSA) for hormone replacement therapy, luteal-phase support in assisted reproduction, and treatment of Abnormal Uterine Bleeding. The medication is available in 100 mg and 200 mg oral tablets.
Who Should Use Prometrium?
- Women undergoing in-vitro fertilisation (IVF) needing luteal-phase support.
- Individuals with confirmed progesterone deficiency (e.g., during menopause).
- Patients prescribed for secondary amenorrhoea or dysfunctional Uterine Bleeding.
- Women requiring hormone replacement therapy (HRT) after menopause.
How Does It Work?
Prometrium mimics natural progesterone by binding to progesterone receptors in the uterus, breast, and brain. This stabilises the endometrium, reduces uterine contractions, and prepares the lining for possible implantation. The effect is similar to the natural hormone that follows ovulation in a normal menstrual cycle.
Why Choose Prometrium?
- Consistent dosing: Tablet form provides precise, reproducible doses.
- Regulatory assurance: HSA-approved with a clear safety profile.
- Convenient administration: Oral intake fits easily into daily routines.
- Off-label uses (e.g., for Migraine prophylaxis) should only be considered after professional consultation.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- 100 mg tablet: one tablet daily, typically taken in the evening.
- 200 mg tablet: one tablet daily, usually in the evening. Dosage may be adjusted by a qualified health professional based on indication.
How to Take
- Swallow the tablet whole with a full glass of water.
- Take it at the same time each day, preferably with food to minimise stomach upset.
Missed Dose
- If you remember within 12 hours, take the missed tablet now.
- If more than 12 hours have passed, skip it and resume the regular schedule.
Overdose
- Seek immediate medical attention if more than the prescribed amount is taken.
- Symptoms may include Drowsiness, Nausea, or breast tenderness.
Special Populations
- Elderly: No dose reduction required unless hepatic impairment is present.
- Renal or hepatic disease: Use the lowest effective dose; monitor liver function.
- Pregnancy: Not indicated; only used under specialist supervision for luteal support.
Lifestyle & Diet
- Avoid grapefruit or grapefruit juice as they can increase progesterone levels.
- Moderate alcohol consumption; excessive intake may alter hormone metabolism.
- No need to restrict calcium-rich foods.
Precautions and Warnings
- Use only under medical supervision for the indicated conditions.
- Do not combine with estrogen therapy without a professional’s advice, as it may increase thrombotic risk.
- Report any signs of liver dysfunction (yellow skin, dark urine) promptly.
Drug Interactions
| Drug Class | Risk | Action |
|---|---|---|
| CYP3A4 inhibitors (e.g., ketoconazole) | ↑ progesterone exposure | Reduce dose or monitor closely |
| Anticonvulsants (e.g., carbamazepine) | ↓ progesterone levels | Consider alternative therapy |
| Rifampin (enzyme inducer) | ↓ progesterone levels | Adjust dose or choose another option |
Potential Side Effects
Common Side Effects
- Headache
- Drowsiness or Fatigue
- Breast tenderness
- Nausea
Less Common Side Effects
- Mood swings
- Mild abdominal cramps
- Weight gain
Serious Side Effects
- Severe allergic reaction (rash, swelling, difficulty breathing) - call emergency services.
- Signs of liver trouble (jaundice, dark urine).
- Unexplained vaginal bleeding.
Who Should Avoid This Medication?
- History of thromboembolic disorders (deep-vein thrombosis, pulmonary embolism).
- Active or past Breast Cancer.
- Uncontrolled Hypertension.
- Known hypersensitivity to progesterone or any tablet excipients.
Storage Instructions
- Store at 20-25 °C (room temperature).
- Keep the bottle tightly closed, away from moisture and light.
- Keep out of reach of children.
Prometrium Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Utrogestan | Micronized progesterone | Soft-gel capsule, similar bioavailability |
| Crinone | Progesterone gel | Vaginal application, useful for localized therapy |
| Endometrin | Vaginal pessary | Direct uterine delivery, higher local concentrations |
Frequently Asked Questions
1. How long does it take for Prometrium to start working?
Effects on the endometrium are typically evident within 5-7 days of consistent daily use.
2. Can I take Prometrium with birth control pills?
Yes, but discuss timing with a health professional, as combined hormonal regimens may affect clotting risk.
3. Is it safe to use Prometrium while breastfeeding?
Progesterone passes into breast milk in low amounts; most clinicians consider it compatible, but professional guidance is recommended.
4. Will Prometrium cause weight gain?
Mild fluid retention can occur, but significant weight gain is uncommon.
5. Can I take Prometrium if I have liver disease?
Use the lowest effective dose and monitor liver function tests regularly.
6. Does alcohol affect Prometrium?
Moderate alcohol is acceptable, but excessive intake may alter hormone metabolism.
7. What should I do if I experience severe mood swings?
Report the symptom promptly; dosage adjustment or alternative therapy may be needed.
8. Can I travel with Prometrium tablets?
Yes, keep them in their original packaging and carry a copy of the prescribing information for customs checks.
9. Is a blood test required to monitor therapy?
Periodic serum progesterone levels may be measured to confirm adequate exposure, especially in fertility protocols.
10. How long can I stay on Prometrium for hormone replacement?
Long-term use is acceptable under medical supervision; periodic review every 6-12 months is advised.
Glossary
- Bioavailability: The proportion of a drug that reaches systemic circulation unchanged.
- CYP3A4: A liver enzyme that metabolises many drugs, including progesterone.
- Endometrium: The inner lining of the uterus that responds to hormonal signals.
- Luteal Phase: The post-ovulation stage of the menstrual cycle when progesterone predominates.
- Micronized: A process that reduces particle size to enhance absorption.
Disclaimer
The information provided here is for general educational purposes and does not replace professional medical advice. Off-label uses should only be considered after consulting a qualified health practitioner. Our online pharmacy offers convenient access to approved medicines, but the final decision to use Prometrium rests with you and your healthcare provider. Always read the patient information leaflet and report any adverse reactions.
Prometrium Drug Class
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How to purchase Prometrium on our Website
To purchase Prometrium | Progesterone on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Prometrium / Progesterone pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Prometrium pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.