Duphaston

Buy Duphaston
duphaston

$39.00

  • Active ingredient: Dydrogesterone
  • Category: Women's Health
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Duphaston (Dydrogesterone) 10mg tablets are available to order from our Singapore pharmacy with reliable delivery. This synthetic progesterone hormone provides effective support for menstrual cycle regulation, endometriosis, and hormone-related conditions by mimicking natural progesterone's effects. Duphaston works by preparing the uterine lining for pregnancy and maintaining hormonal balance throughout the menstrual cycle. It is an ideal solution for women seeking reliable hormonal support for cycle regulation and reproductive health management.

Table of contents

Duphaston (Dydrogesterone) Buyer and Patient Handbook in Singapore

What is Duphaston?

Duphaston is a synthetic progestogen tablets (10 mg) used to treat hormonal disorders in women. It belongs to the class of progesterone-like agents and is indicated for conditions such as luteal phase deficiency, irregular menses, and preparation of the uterine lining for assisted reproduction. The product is approved by the Singapore Health Sciences Authority (HSA) and holds FDA and EMA clearances. It is supplied as oral tablets.

Who Should Use Duphaston?

  • Women of reproductive age experiencing luteal-phase insufficiency.
  • Patients undergoing in-vitro fertilisation (IVF) or other assisted reproductive techniques.
  • Women with irregular menstrual cycles or secondary amenorrhoea.
  • Those requiring hormonal support during the luteal phase of the menstrual cycle.

How Does It Work?

Duphaston mimics natural Progesterone, binding to progesterone receptors in the uterus and ovaries. This stimulates the endometrium to become receptive, stabilises the menstrual cycle, and supports early pregnancy. Think of it as a “key” that unlocks the uterine lining, allowing it to thicken appropriately. The medication has a low risk of abuse because it does not produce psychoactive effects.

Why Choose Duphaston?

Choosing Duphaston offers a well-studied, high-purity progestogen with predictable absorption. For patients seeking a reliable hormone supplement, it provides consistent plasma levels and minimal androgenic activity. While off-label uses exist (e.g., certain menstrual-related mood disorders), always discuss them with a qualified healthcare professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 10 mg tablet taken once daily as prescribed for the specific indication.

How to Take

  • Swallow the tablet whole with a glass of water.
  • Take it at the same time each day, preferably after a meal to minimise stomach upset.

Missed Dose

  • If you remember within 12 hours, take the missed tablet.
  • If more than 12 hours have passed, skip the missed dose and continue with the regular schedule-do not double-dose.

Overdose

  • Seek immediate medical attention or contact the HSA Poison Centre (180-222-1414).
  • Symptoms may include Nausea, Vomiting, or heavy menstrual bleeding.

Special Populations

  • Elderly: No specific dose adjustment, but monitor for liver function.
  • Renal or hepatic impairment: Use with caution; dose may be reduced based on clinical judgment.
  • Pregnancy: Intended for use in early pregnancy under medical supervision; discontinue if no longer required.

Lifestyle & Diet

  • Avoid grapefruit juice, which can increase plasma concentration.
  • Moderate alcohol intake; excessive drinking may exacerbate menstrual irregularities.
  • Maintain a balanced diet rich in calcium and vitamin D to support bone health while on progestogens.

Precautions and Warnings

  • Do not use if you have a known allergy to dydrogesterone or any tablet excipients.
  • Caution in patients with a history of thromboembolic disease, uncontrolled Hypertension, or severe liver disease.
  • Report any unexpected vaginal bleeding or severe abdominal Pain promptly.

Drug Interactions

Drug Class Risk Action
Antifungals (e.g., ketoconazole) ↑ Duphaston levels Monitor for excess progesterone effects
Antiepileptics (e.g., carbamazepine) ↓ Duphaston efficacy Consider alternative progestogen
CYP3A4 inducers (e.g., rifampicin) ↓ Duphaston levels Adjust dose or switch therapy

Potential Side Effects

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood swings

Less Common Side Effects

  • Dizziness
  • Abdominal bloating
  • Skin rash

Serious Side Effects

  • Severe allergic reaction ( swelling of face, difficulty breathing ) - seek urgent care
  • Unexplained vaginal bleeding or spotting
  • Signs of blood clots ( leg pain, swelling, sudden shortness of breath ) - call emergency services

Who Should Avoid This Medication?

  • Women with active or history of Breast Cancer
  • Patients with uncontrolled Diabetes mellitus
  • Individuals with known hypersensitivity to dydrogesterone or any tablet component
  • Those with severe liver disease (Child-Pugh C)

Storage Instructions

  • Keep the tablets in their original blister pack.
  • Store at room temperature, ≤ 25 °C, away from direct sunlight and moisture.
  • Keep out of reach of children and pets.

Duphaston Alternatives

Name Class Key Difference
Micronor Progestogen Micronised natural progesterone
Utrogestan Progestogen Micronised micronised natural source
Vaginal progesterone gel Progestogen Local delivery, reduces systemic exposure

Frequently Asked Questions

How long does it take for Duphaston to regulate my cycle?

Typically, cycle regularity improves within 2-3 months of consistent use, though individual response varies.

Can I take Duphaston while breastfeeding?

Safety in lactation has not been fully established; discuss alternatives with your clinician.

Is it safe to consume coffee while on Duphaston?

Moderate coffee intake (≤ 2 cups per day) does not affect Duphaston’s efficacy.

What should I do if I experience persistent nausea?

Take the tablet with food and a full glass of water; if nausea continues, consult your healthcare provider.

Does Duphaston interact with oral contraceptives?

No clinically significant interaction has been reported, but combined use should be supervised by a professional.

Can I use Duphaston for endometriosis pain relief?

It is sometimes prescribed off-label for endometriosis; discuss risks and benefits with a specialist.

Will Duphaston affect my mood?

Some users report mood swings; if symptoms are severe, seek medical advice.

How should I store Duphaston when traveling abroad?

Keep the medication in the original packaging, avoid excessive heat, and carry it in hand luggage to prevent loss.

Glossary

  • Progestogen: A hormone that mimics the action of natural progesterone, essential for regulating the menstrual cycle and maintaining pregnancy.
  • Luteal phase: The post-ovulation portion of the menstrual cycle when progesterone prepares the uterine lining for implantation.
  • Bioequivalence: Demonstrates that a generic product delivers the same amount of active ingredient into the bloodstream as the reference brand.

Disclaimer

The information presented here is for general educational purposes and does not replace professional medical advice. Off-label uses should only be considered after discussion with a qualified healthcare provider. Readers are responsible for verifying the suitability of any medication for their personal health condition. Our service provides medication information and convenient ordering through an online platform; it does not prescribe or dispense drugs. Always consult a licensed clinician before starting or changing any therapy.

Duphaston Properties

  • Original Manufacturer: Abbott Laboratories
  • Clinical use: Progestogen therapy
  • Spectrum of activity: Progestogen
  • Mechanism of action: Mimics progesterone to stabilize the uterine lining
  • Classification: Progestogen
  • Recommended Dosage: 10-20 mg daily, depending on condition
  • Basic Side Effects: Headache, Fatigue, Nausea
  • Moderate Side Effects: Breast tenderness, Mood changes
  • Serious Side Effects: Thromboembolism, High blood pressure

How to purchase Duphaston on our Website

To purchase Duphaston | Dydrogesterone on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Duphaston / Dydrogesterone pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Duphaston pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.72/173
Duphaston

First week on Duphaston and it's a rollercoaster. My spotting stopped almost immediately, which is great, but the bloating is unreal. I look pregnant. Also getting these weird headaches that come and go. My gynae said to push through for at least one cycle, so I'm sticking with it. Taking it right after dinner seems to help a bit with the nausea.

Mei L. Kuala Lumpur, Malaysia

Doc prescribed this to regulate my cycle before IVF. On day 5 now. The fatigue hit me hard by day 3, I could sleep for 10 hours and still feel tired. Mood swings are something else too - cried at a shampoo commercial yesterday. Hoping this is just my body adjusting. Pro tip: set an alarm to take it at the exact same time every day, it makes a difference.

Sarah T. Singapore, Singapore

Been on Duphaston for 3 years for endometriosis. It's been a lifesaver for the pain, my periods are finally manageable. The key is to take it with food, otherwise my stomach gets upset. I did gain about 4kg over the first year, but it stabilized. Small price to pay for being functional. Sometimes I split the 10mg pill if I feel my symptoms are mild that month, seems to work fine.

Anita R. Jakarta, Indonesia

Using it for 8 months for irregular periods. It works, my cycle is like clockwork now. But the breast tenderness is no joke, especially the week before my period. I also noticed my hair shedding more when I first started, but it slowed down after 3 months. Drink lots of water, it helps with the bloating. I skip the occasional dose if I know I'm going out for drinks, doesn't seem to affect me.

Chloe P. Manila, Philippines

Two years on Duphaston for luteal phase defect. It's the only thing that helped me carry my pregnancy to term. The side effects were rough at first - acne breakout and moodiness - but they faded after the first two cycles. Now I don't even notice I'm on it. I take it at 9 PM sharp with a small snack. Don't take it on an empty stomach, trust me on that.

Priya S. Penang, Malaysia

Prescribed for heavy bleeding. It definitely lightens the flow, but the trade-off is constant low-level nausea and this metallic taste in my mouth. I found sucking on a lemon drop right after taking the pill helps with the taste. My skin has actually cleared up, which was a nice surprise. It's okay, not great, but better than the alternative.

Maria G. Cebu, Philippines

My experience is mixed. It completely stopped my spotting, which was the goal. But it also killed my libido, which my doctor didn't warn me about. It's like a switch flipped. I'm less irritable on it, which my husband appreciates, but the other side effect is frustrating. Thinking of asking to lower the dose or try something else after this pack.

Ling W. Bangkok, Thailand

Took Duphaston for 10 days to induce a period. It worked, my period came 3 days after finishing the course. But the emotional dip during those 10 days was intense. Felt really down and anxious for no reason. Also had crazy vivid dreams every night. Glad I only needed it short-term, not sure I could handle that long-term. Taking it right before bed helped me sleep through the worst of the moodiness.

Dewi A. Bali, Indonesia

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