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Hyplon (Zaleplon) Buyer and Patient Handbook in Singapore

Hyplon (Zaleplon) is a short-acting sleep medication belonging to the non-benzodiazepine hypnotic class, commonly prescribed for the short-term treatment of Insomnia. It is approved by the Health Sciences Authority (HSA) and is available as a 10 mg oral pill.

What is Hyplon?

Hyplon contains the active ingredient Zaleplon, a sedative-hypnotic that helps you fall asleep faster. It is indicated for adults who have difficulty initiating sleep. The medication is marketed in a 10 mg tablet form.

Who Should Use Hyplon?

• Adults (18 years and older) experiencing difficulty falling asleep.
• Individuals without a history of severe liver disease.
• Patients without known hypersensitivity to Zaleplon or related compounds.

How Does Hyplon Work?

Zaleplon binds selectively to the GABA-A receptor complex, enhancing the inhibitory effect of the neurotransmitter GABA. This action reduces neuronal activity, promoting sleep onset within 15-30 minutes. The drug’s short half-life (about 1 hour) means it is less likely to cause next-day Drowsiness, but it also carries a low risk of dependence if used repeatedly.

Why Choose Hyplon?

• Rapid onset: Helps you fall asleep quickly, ideal for occasional sleepless nights.
• Short duration: Minimises morning grogginess, suitable for people who need to stay alert after bedtime.
• Generic option: Often more affordable than brand-only formulations while meeting the same bio-equivalence standards.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Standard dose: 10 mg taken orally once per night, right before bedtime.

How to Take

• Swallow the tablet whole with a small glass of water.
• Take it only when you can dedicate a full night (7-8 hours) to sleep.

Missed Dose

• If you forget to take a dose, skip it and resume the regular schedule the next night. Do not take a double dose.

Overdose

• In case of suspected overdose, seek immediate medical attention or call Singapore’s emergency number 995.

Special Populations

• Elderly: Start with a reduced dose of 5 mg if tolerability is a concern.
• Renal or hepatic impairment: Dose adjustment may be required; consult a healthcare professional.
• Pregnancy & breastfeeding: Use only if the potential benefit outweighs the risk.

Lifestyle & Diet

• Avoid alcohol, as it can enhance sedative effects.
• Limit caffeine intake in the late afternoon and evening.
• Grapefruit juice does not significantly interact with Zaleplon, but maintain a balanced diet.

Precautions and Warnings

• Do not operate heavy machinery or drive after taking Hyplon until you know how it affects you.
• Inform your healthcare provider of any history of Depression, suicidal thoughts, or substance abuse.
• Discontinue use if you experience severe Allergic Reactions (rash, swelling, difficulty breathing).

Drug Interactions

Potential Side Effects

Common Side Effects

• Drowsiness the next day (rare)
• Headache
• Dizziness

Less Common Side Effects

• Nausea
• Dry mouth
• Unusual dreams

Serious Side Effects

• Allergic reaction (rash, itching, swelling) - seek medical help immediately
• Mood changes, depression, or suicidal thoughts - contact a healthcare professional promptly

Who Should Avoid This Medication?

• Individuals with known hypersensitivity to Zaleplon or any formulation component.
• Patients with severe hepatic impairment.
• Those with a history of complex sleep-related behaviors (e.g., sleepwalking, sleep-driving).

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at room temperature (15-30 °C).
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Hyplon Alternatives

Frequently Asked Questions

How long does Hyplon stay in my system?

Hyplon has an elimination half-life of about 1 hour, so it is usually cleared within 4-6 hours after the last dose.

Can I take Hyplon with a cup of coffee in the morning?

A moderate amount of coffee is generally safe, but avoid excessive caffeine that could interfere with sleep quality.

Is it safe to use Hyplon on consecutive nights?

Short-term use (≤2 weeks) is considered safe; longer continuous use should be discussed with a healthcare professional.

What should I do if I feel groggy the next morning?

If grogginess persists, reduce the dose or take the medication only on nights when you have no early commitments.

Can I combine Hyplon with over-the-counter sleep aids?

Combining with other sedatives can increase the risk of excessive sedation; consult a healthcare professional before doing so.

Does Hyplon affect my ability to drive the next day?

Most users experience minimal next-day impairment, but you should test your alertness before driving after the first dose.

What happens if I miss a dose?

Simply skip the missed dose and resume your regular bedtime schedule; do not double-dose.

Is Hyplon addictive?

Physical dependence is low when used as directed for short periods, but misuse can lead to psychological dependence.

Glossary

• GABA (Gamma-aminobutyric acid): The main inhibitory neurotransmitter in the brain that promotes relaxation and sleep.
• Half-life: The time required for the concentration of a drug in the plasma to reduce by half.
• CYP3A4: An enzyme in the liver that metabolises many medications; inhibitors can raise drug levels.

Disclaimer

The information provided here is for general educational purposes only and should not replace professional medical advice. Hyplon may be used off-label only under the guidance of a qualified healthcare professional. Readers are responsible for verifying details and discussing any medication use with their own clinician. Our platform offers convenient access to licensed pharmacies in Singapore; all purchases are subject to local regulations and the discretion of the dispensing pharmacist.