Amaryl

Buy Amaryl
amaryl

$18.80

  • Active ingredient: Glimepiride
  • Category: Diabetes
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Generic Amaryl (Glimepiride) 1 mg / 2 mg / 4 mg tablets are available to buy from our Singapore online pharmacy with efficient delivery. As a sulfonylurea, it stimulates insulin release from the pancreas to help regulate glucose levels in diabetes management. It enhances beta-cell sensitivity to improve metabolic control. This medication is ideal for adults with type 2 diabetes aiming for stable blood sugar through oral therapy.

Table of contents

Amaryl (Glimepiride) Buyer and Patient Handbook in Singapore

What is Amaryl?

Amaryl is a sulfonylurea oral tablet used to lower blood glucose in Type 2 Diabetes. It belongs to the class of insulin-secretagogues that help the pancreas release more insulin. Approved by the FDA, EMA and Singapore’s Health Sciences Authority, it is available in 1 mg, 2 mg and 4 mg tablets.

Who Should Use Amaryl?

  • Adults diagnosed with type 2 diabetes mellitus who need additional glucose control beyond diet and exercise.
  • Patients whose blood-sugar targets are not achieved with Metformin alone.
  • Individuals without a history of severe hypoglycaemia or sulfonylurea allergy.

How Does It Work?

Amaryl stimulates pancreatic β-cells to release extra insulin, much like pressing the accelerator when the engine needs more power. This increased insulin lowers circulating glucose, helping to keep levels within the target range. Note: It can cause hypoglycaemia, especially if meals are skipped or alcohol is consumed.

Why Choose Amaryl?

Amaryl offers a proven, cost-effective option for glycaemic control when added to existing therapy. As a brand formulation, it provides consistent bioavailability, while generic glimepiride tablets are also available for budget-conscious patients. Off-label uses should only be considered after professional consultation.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 1 mg: Starting dose for most adults.
  • 2 mg: May be increased after 2-4 weeks if glucose targets are not met.
  • 4 mg: Maximum recommended daily dose.

How to Take

  • Swallow the tablet whole with a full glass of water.
  • Take it once daily with breakfast or the first main meal.
  • Do not crush or chew the tablet.

Missed Dose

  • If you remember within 12 hours, take it as soon as possible.
  • If more than 12 hours have passed, skip the missed dose and resume your regular schedule.

Overdose

  • Seek immediate medical attention if you suspect an overdose.
  • Symptoms may include severe sweating, confusion, or fainting due to low blood sugar.

Special Populations

  • Elderly: Start at 1 mg; monitor closely for hypoglycaemia.
  • Renal impairment: Dose may need reduction; consult a healthcare professional.
  • Pregnancy & lactation: Generally avoided; discuss alternatives with your doctor.

Lifestyle & Diet

  • Food: Take with meals to reduce the risk of low blood sugar.
  • Alcohol: Limit intake; excessive alcohol can increase hypoglycaemia risk.
  • Grapefruit: No significant interaction, but maintain a balanced diet.

Precautions and Warnings

  • Hypoglycaemia: Recognise signs such as shakiness, sweating, and confusion.
  • Allergy: Discontinue if you develop rash, itching, or swelling.
  • Kidney disease: Use the lowest effective dose and monitor renal function.
  • Heart failure: Use with caution; report worsening symptoms promptly.

Drug Interactions

Drug Class Risk Action
Non-β-blocker antihypertensives May mask hypoglycaemia symptoms Monitor blood glucose closely
NSAIDs Can impair renal function Adjust glimepiride dose if needed
Rifampin Reduces glimepiride levels Consider alternative antidiabetic agent

Potential Side Effects

Common Side Effects

  • Mild hypoglycaemia
  • Weight gain
  • Nausea or stomach upset

Less Common Side Effects

  • Skin rash
  • Headache
  • Dizziness

Serious Side Effects

  • Severe hypoglycaemia (loss of consciousness) - call emergency services
  • Hepatotoxicity (jaundice, dark urine) - seek immediate medical help
  • Allergic reaction (swelling, trouble breathing) - seek urgent care

Who Should Avoid This Medication?

  • Known hypersensitivity to glimepiride or sulfonylureas.
  • Patients with type 1 diabetes or diabetic ketoacidosis.
  • Individuals with chronic liver disease or severe Renal Failure (eGFR < 30 mL/min/1.73 m²).

Storage Instructions

  • Keep tablets in the original blister pack.
  • Store at 15 °C-30 °C, away from moisture and direct sunlight.
  • Keep out of reach of children and pets.

Amaryl Alternatives

Name Class Key Difference
Glimepiride generic Sulfonylurea Same active ingredient, lower cost
Metformin Biguanide Reduces hepatic glucose production; no hypoglycaemia risk
DPP-4 inhibitors (e.g., sitagliptin) Incretin-based Weight-neutral, lower hypoglycaemia risk

Frequently Asked Questions

How quickly does Amaryl start working?

Amaryl begins lowering blood glucose within 2-4 hours after the first dose, with full effect seen after several days of consistent use.

Can I take Amaryl if I drink coffee?

Yes, moderate coffee consumption does not affect Amaryl’s efficacy, but avoid excessive caffeine that may cause dehydration.

What should I do if I experience a low blood sugar episode?

Consume 15 g of fast-acting carbohydrate (e.g., glucose tablets, fruit juice), re-check glucose after 15 minutes, and repeat if still low. If you cannot treat yourself, ask someone for help or call emergency services.

Is it safe to exercise while on Amaryl?

Exercise is beneficial, but monitor blood glucose before, during, and after activity to prevent hypoglycaemia. Adjust food intake or timing of the dose if needed.

Can I take Amaryl with other oral diabetes medicines?

Amaryl can be combined with metformin, SGLT2 inhibitors, or DPP-4 inhibitors under professional guidance; avoid duplicate sulfonylurea therapy.

Does Amaryl cause weight gain?**

Some patients experience modest weight gain due to increased insulin levels; maintaining a balanced diet and regular exercise can mitigate this effect.

How often should I have my blood sugar checked?

Check fasting glucose once daily and post-prandial glucose 2 hours after meals; more frequent testing may be needed during dose adjustments.

Will my health insurance cover Amaryl in Singapore?**

Coverage varies by insurer and plan; review your policy or contact your insurer for specific details.

Glossary

  • Sulfonylurea: A class of drugs that stimulate insulin release from the pancreas.
  • Hypoglycaemia: Abnormally low blood glucose, typically below 3.9 mmol/L.
  • Bioavailability: The proportion of a drug that enters the circulation and can have an active effect.

Disclaimer

This handbook provides general information for educational purposes only and does not replace professional medical advice. Off-label uses should be discussed with a qualified healthcare provider. Readers are responsible for verifying the suitability of Amaryl for their personal health needs and for abiding by Singapore’s regulations when purchasing through our online pharmacy platform. Always consult a qualified doctor or pharmacist before starting or changing any medication regimen.

Amaryl Properties

  • Original Manufacturer: Sanofi
  • Clinical use: Oral antidiabetic drug used to manage type 2 diabetes mellitus.
  • Spectrum of activity: Primarily used for controlling blood glucose levels in patients with type 2 diabetes.
  • Mechanism of action: Enhances the secretion of insulin from the pancreas by closing potassium channels in beta cells.
  • Classification: Sulfonylurea
  • Recommended Dosage: 1-4 mg once daily, adjusted based on blood glucose levels.
  • Basic Side Effects: Headache, Dizziness, Nausea
  • Moderate Side Effects: Hypoglycemia, Weight gain
  • Serious Side Effects: Allergic reactions, Hepatotoxicity

Amaryl Drug Class

Sulfonylureas

Amaryl Connected Conditions

How to order Amaryl from our Online Pharmacy

To order Amaryl | Glimepiride on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Amaryl / Glimepiride pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Amaryl pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.71/177
Amaryl

Been on amaryl for about three weeks. It definitely brings my sugar down, that's for sure. But man, the first few days were rough. Felt super dizzy and tired, like I could sleep for a week. My doc said it might get better. The key for me is to take it right after a meal, never on an empty stomach.

Wei L. Kuala Lumpur, Malaysia

Just started 1mg last month. It's scary how quickly it works. My morning reading is finally under control, but I had a hypo episode last week. Felt shaky and confused until I drank some fruit juice. Learned my lesson: gotta be super careful with portions now. My aunty who's been on it for years told me to always carry candy.

Maria S. Manila, Philippines

Two years on glimepiride 2mg. It's kept my A1C in check, but it's a constant balancing act. My biggest tip: eat a small, consistent snack like a piece of fruit or a few crackers about 3 hours after taking the pill with breakfast. That stops the late-morning slump. Still get some indigestion, but it's better than the alternatives.

Siti R. Singapore

Been using this for 5 years, now on 4mg. It works, but the weight gain is real and frustrating. I've had to double down on walking after dinner. I found that splitting the dose with my doc's OK-2mg in the morning, 2mg with dinner-helps avoid a huge sugar crash at lunchtime. You really have to listen to your body.

Chandra K. Bangkok, Thailand

It controls my sugar effectively, no doubt. But the trade-off is the bloating. Feels like I'm pregnant sometimes. What helps me is drinking a lot of water and avoiding oily foods, especially for breakfast. My numbers are good though, so I guess I'll stick with it.

Anita D. Jakarta, Indonesia

After a year, my main issue is the metallic taste in my mouth. Very annoying. But it's the only med that keeps my post-meal spikes low without making me feel weird. I chew sugar-free gum, which helps a bit. You get used to it, I suppose. Just part of the routine now.

David T. Penang, Malaysia

It's weird. My blood sugar is perfect, better than it's been in years. But my skin has gotten more sensitive to the sun. Got a rash after a day out. Doc confirmed it's a rare side effect. So now it's amaryl, sunscreen, and a hat every day. A fair trade for good health, but annoying.

Ling L. Singapore

Works for glucose but my vision gets a bit blurry sometimes, especially in the afternoon. Doc says it might be the medication causing low sugar effects. Started having a small yogurt at 3 PM and it's helped. Frustrating to have to micromanage like this, but at least there's a workaround.

Ramon G. Pampanga, Philippines

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