Aciphex

Buy Aciphex
aciphex

$16.80

  • Active ingredient: Rabeprazole
  • Category: Digestive Health
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Generic Aciphex (Rabeprazole) 10 mg / 20 mg tablets are available to order from our Singapore pharmacy with reliable delivery. This proton pump inhibitor decreases stomach acid production to heal and prevent gastrointestinal issues like heartburn and ulcers. It effectively blocks acid-secreting pumps in the stomach lining for prolonged relief. It is suitable for adults dealing with frequent digestive discomfort who need consistent acid suppression.

Table of contents

Aciphex (Rabeprazole) Buyer and Patient Handbook in Singapore

What is Aciphex?

Aciphex is a rabeprazole-based proton-pump inhibitor (PPI) used to reduce stomach acid production. It belongs to the gastrointestinal drug class and is indicated for conditions such as gastro-oesophageal reflux disease (GERD), erosive oesophagitis, and Zollinger-Ellison Syndrome. The product is approved by the Health Sciences Authority (HSA) of Singapore and is supplied as oral pills.

Who Should Use Aciphex?

  • Adults diagnosed with GERD or persistent heartburn
  • Patients with confirmed erosive oesophagitis
  • Individuals requiring ulcer protection while on NSAIDs
  • Adults with hyper-secretory acid disorders (e.g., Zollinger-Ellison syndrome)
  • Patients whose physicians have assessed that acid suppression is appropriate

How Does It Work?

Aciphex blocks the hydrogen-potassium ATPase enzyme (the “acid pump”) in the gastric parietal cells, preventing the final step of acid secretion. By shutting down this pump, the medication lowers the acidity of the stomach, allowing irritated tissue to heal. The effect typically begins within an hour, with maximal suppression after 2-3 days of regular dosing.

Why Choose Aciphex?

  • Proven efficacy: Clinical trials show rapid symptom relief and high healing rates for erosive oesophagitis.
  • Convenient dosing: Once-daily dosing simplifies adherence compared with older PPIs that required twice-daily intake.
  • Availability in Singapore: Aciphex is listed on the HSA-approved drug register, and generic rabeprazole alternatives are also widely accessible, offering cost-saving options.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 10 mg tablet: One tablet once daily for maintenance therapy after healing.
  • 20 mg tablet: One tablet once daily for initial treatment of GERD or erosive oesophagitis (typically 4-8 weeks).

How to Take

  1. Swallow the tablet whole with a full glass of water.
  2. Take it 30 minutes before breakfast for optimal acid suppression.
  3. Do not crush or chew the tablet, as this may affect its release mechanism.

Missed Dose

  • If you remember the missed dose within 12 hours, take it immediately.
  • If it is later than 12 hours, skip the missed dose and resume your regular schedule. Do not double-dose.

Overdose

  • Immediate action: Contact Singapore’s National Poison Centre (180-222-5555) or seek emergency care.
  • Symptoms: May include Nausea, Vomiting, dizziness, or abdominal Pain. No specific antidote exists; treatment is supportive.

Special Populations

  • Elderly: Start with the lowest effective dose; monitor for kidney function.
  • Renal impairment: No dose adjustment needed for mild to moderate impairment; severe impairment requires physician review.
  • Pregnancy & lactation: Category B2 (Australia); limited data in Singapore. Use only if benefits outweigh risks.

Lifestyle & Diet

  • Avoid grapefruit juice within 2 hours of dosing, as it can increase plasma levels.
  • Limit alcohol if you experience stomach irritation; moderate consumption is generally safe.
  • Maintain a healthy weight and avoid late-night meals to reduce reflux episodes.

Precautions and Warnings

  • Long-term use (≥1 year) may increase the risk of osteoporosis-related fractures; ensure adequate calcium and vitamin D intake.
  • Infection risk: Reduced stomach acid can predispose to Clostridioides difficile infection; report persistent Diarrhea.
  • Hypersensitivity: Discontinue immediately if you develop rash, swelling, or breathing difficulty.

Drug Interactions

Drug Class Interaction Risk Management
Antiplatelet agents (e.g., clopidogrel) Reduced antiplatelet effect Consider alternative PPI or adjust therapy
Ketoconazole / Itraconazole Decreased antifungal absorption Separate administration by ≥2 h
Warfarin Possible increased INR Monitor INR more frequently

Potential Side Effects

Common Side Effects

  • Headache
  • Diarrhea or constipation
  • Mild abdominal pain

Less Common Side Effects

  • Nausea or vomiting
  • Flatulence
  • Dizziness

Serious Side Effects

  • Severe rash or Stevens-Johnson syndrome - seek medical help immediately
  • Signs of kidney problems (e.g., reduced urine output, swelling)
  • Persistent vomiting or dehydration

Who Should Avoid This Medication?

  • Patients with known hypersensitivity to rabeprazole or any excipients
  • Individuals with a history of severe hepatic impairment (use only under specialist advice)
  • Patients taking concomitant drugs that require an elevated gastric pH for absorption (e.g., certain Antivirals) unless supervised

Storage Instructions

  • Keep the tablets in their original container, tightly closed.
  • Store at 20-25 °C (68-77 °F); protect from excess heat and moisture.
  • Keep out of reach of children and pets.

Aciphex Alternatives

Name Class Key Difference
Generic Rabeprazole (e.g., Rabacid) PPI Same active ingredient, lower cost
Omeprazole (Prilosec) PPI Slightly slower onset, different metabolic pathway
Pantoprazole (Pantoloc) PPI Higher dose flexibility, useful in refractory cases

Frequently Asked Questions

How quickly will I feel relief after starting Aciphex?

Most patients notice a reduction in heartburn within 1 hour, with full symptom control developing over 2-3 days of daily use.

Can I take Aciphex with coffee?

Yes, but avoid consuming coffee on an empty stomach as it may temporarily increase acid production, counteracting the medication’s effect.

Is it safe to use Aciphex while taking ibuprofen?

Aciphex can protect the stomach lining from ibuprofen-related ulcers, but you should still use the lowest effective ibuprofen dose and discuss long-term combined use with your healthcare provider.

What should I do if I experience persistent diarrhea?

Report the symptom to a healthcare professional promptly, as it could indicate Clostridioides difficile infection, especially with prolonged acid suppression.

Can I stop Aciphex abruptly after a few weeks?

For short-term therapy (≤4 weeks) stopping is usually safe, but gradual tapering is recommended after long-term use to prevent rebound acid hypersecretion.

Does Aciphex interact with vitamin B12 supplements?

Long-term use may reduce vitamin B12 absorption; consider periodic monitoring of B12 levels if therapy exceeds 6 months.

Is Aciphex suitable for children?

Aciphex is not approved for pediatric use in Singapore; a pediatric formulation of rabeprazole may be prescribed under specialist guidance.

How should I store the medication during travel?

Keep the tablets away from direct sunlight and high temperatures, ideally in a cool, dry bag. Do not expose them to airline cargo holds where temperature can exceed recommended limits.

Glossary

  • Proton-pump inhibitor (PPI): A drug class that blocks the final step of gastric acid production.
  • Rebound acid hypersecretion: An increase in stomach acid after stopping a PPI abruptly.
  • Bioavailability: The proportion of a drug that enters systemic circulation and can have an active effect.

Disclaimer

The information presented here is for general educational purposes and does not replace professional medical advice. Off-label use should only be considered after consulting a qualified healthcare professional. Readers are responsible for verifying the suitability of Aciphex for their individual health needs. Our platform provides access to licensed pharmacies in Singapore; all purchases are subject to the buyer’s own discretion and compliance with local regulations. Always discuss any medication changes with a qualified clinician.

Aciphex Properties

  • Original Manufacturer: Eisai Inc.
  • Clinical use: Used for treating acid-related gastrointestinal conditions.
  • Spectrum of activity: Reduces gastric acid secretion.
  • Mechanism of action: Inhibits the proton pump in gastric parietal cells, reducing acid production.
  • Classification: Proton pump inhibitor (PPI)
  • Recommended Dosage: 10-20 mg once daily, adjusted based on the condition being treated.
  • Basic Side Effects: Headache, Diarrhea, Nausea
  • Moderate Side Effects: Abdominal pain, Constipation
  • Serious Side Effects: Bone fractures, Acute interstitial nephritis

Aciphex Drug Class

Proton Pump Inhibitors

How to purchase Aciphex on our Online Drugstore

To purchase Aciphex | Rabeprazole on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Aciphex / Rabeprazole pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Aciphex pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.76/147
Aciphex

Been on Aciphex for about 3 weeks now. The heartburn is way down, I can actually sleep through the night. But man, the headaches hit me hard for the first few days. My pharmacist said to take it with food, not just water, and that's helped a lot. Still getting used to it.

Wei L. Singapore, Singapore

Doctor just switched me from omeprazole. It's... okay? The burning sensation is less intense, but I feel bloated all the time now. And my stomach feels weirdly sensitive. Giving it another week to see if my body adjusts. Taking it first thing in the morning is a must.

Maria D. Manila, Philippines

Two years on Aciphex 20mg. It's been a lifesaver for my GERD. The trick is to be religious about it - 30 mins before breakfast, no exceptions. If I skip a day, the acid comes back with a vengeance. Only downside is I get joint pain sometimes, but it's better than the alternative.

Ahmad R. Kuala Lumpur, Malaysia

My GI doc said I might need to be on this long-term. It controls the acid, but I've had to seriously up my water intake because of the dry mouth. Also learned the hard way: never take it with orange juice, makes it totally useless. Stick to plain water.

Chandra S. Jakarta, Indonesia

After 6 months, my stomach is finally calm. But I had to figure out my own routine. I split the 20mg pill in half and take one half in the morning, one before dinner. Works better for me than one big dose. Doctor said it's fine as long as the pill isn't a time-release type.

Siti K. Penang, Malaysia

It stops the acid, but now I'm dealing with constant gas and bloating. Like, really bad. I started eating yogurt every day and that seems to help a bit. It's a trade-off. I don't miss the pain, but this new issue is frustrating. Maybe it's not for everyone.

David T. Bangkok, Thailand

Strange one. Aciphex completely fixed my acid reflux, which was amazing. But after a few months, I started feeling more anxious and had trouble sleeping. My GP thinks it might be affecting my magnesium levels. So it's great for my stomach, not so great for my head.

Anjali P. Singapore, Singapore

I take it for Barrett's esophagus. It's effective, no doubt. But the long-term use worries me. I get blood tests every 6 months to check my B12 and magnesium. It's a necessary evil. Pro tip: get a pill cutter, the 20mg is often cheaper than the 10mg.

Ling W. Cebu, Philippines

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