Buy Pentasa
pentasa
$45.60
- Active ingredient: Mesalamine
- Category: Digestive Health
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Pentasa (Mesalamine) 400mg tablets are available from our Singapore pharmacy with nationwide delivery. This anti-inflammatory medication works directly in the colon to reduce inflammation in the intestinal lining, helping to control symptoms of ulcerative colitis and Crohn's disease. It is essential for adults with inflammatory bowel conditions who need targeted treatment to maintain remission and improve digestive health.
Table of contents
- Pentasa (Mesalamine) Buyer and Patient Handbook in Singapore
- What is Pentasa?
- Who Should Use Pentasa?
- How Does It Work?
- Why Choose Pentasa?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Pentasa Alternatives
- Frequently Asked Questions
- How quickly will Pentasa start working?
- Can I drink coffee or alcohol while taking Pentasa?
- What should I do if I experience no improvement after a month?
- Is it safe to use Pentasa together with probiotic supplements?
- Can I switch from a generic mesalamine to Pentasa without a doctor’s instruction?
- Does Pentasa affect blood sugar or cholesterol levels?
- What is the maximum daily dose allowed?
- Will Pentasa cure ulcerative colitis?
- Glossary
- Disclaimer
- Pentasa Properties
- Pentasa Drug Class
- Pentasa Connected Conditions
- How to purchase Pentasa on our Online Drugstore
- Reviews
- Write your review
Pentasa (Mesalamine) Buyer and Patient Handbook in Singapore
What is Pentasa?
Pentasa is a mesalamine-based medication belonging to the 5-aminosalicylic acid (5-ASA) class, used to treat Ulcerative Colitis. It helps reduce inflammation in the lining of the colon and is approved by both the Health Sciences Authority (HSA) of Singapore and international regulators such as the FDA and EMA. The drug is supplied as oral pills.
Who Should Use Pentasa?
- Adults diagnosed with mild-to-moderate ulcerative colitis
- Patients requiring maintenance therapy to prevent flare-ups
- Individuals whose disease is limited to the colon (no small-bowel involvement)
How Does It Work?
Pentasa releases mesalamine throughout the gastrointestinal tract, where the compound blocks inflammatory chemicals called prostaglandins and leukotrienes. Think of it as a “fire extinguisher” that dampens the local blaze of inflammation without affecting the rest of the body. The drug has a very low potential for abuse.
Why Choose Pentasa?
Pentasa offers a controlled-release formulation that delivers mesalamine directly to the colon, providing more consistent symptom control compared with some immediate-release products. While generic mesalamine tablets are available at a lower price, Pentasa’s tablet design may give better tolerability for certain patients. Off-label uses exist but should be discussed with a healthcare professional.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- 400 mg tablet taken four times daily (total 160 mg per day) for induction of remission in ulcerative colitis, or
- 400 mg tablet taken twice daily (total 800 mg per day) for maintenance therapy, as directed by the prescriber.
How to Take
- Swallow the tablet whole with a full glass of water.
- It may be taken with or without food; consistent timing helps maintain steady drug levels.
Missed Dose
If you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and continue with your regular schedule-do not double-dose.
Overdose
If you suspect an overdose, seek immediate medical attention or contact the local poison-control centre (Singapore: 180-222-1111).
Special Populations
- Elderly: Dose may need adjustment based on kidney function.
- Renal impairment: Use the lowest effective dose; monitor renal parameters.
- Pregnancy & breastfeeding: Generally considered safe, but discuss with a healthcare professional.
Lifestyle & Diet
- Avoid taking the tablet with grapefruit juice, as it can increase mesalamine levels.
- Maintain adequate hydration; large amounts of fluid help the medication travel through the colon.
Precautions and Warnings
- Monitor kidney function periodically, especially if you have pre-existing renal disease.
- Report any signs of severe abdominal Pain, blood in stool, or new onset of fever.
- Discontinue use and seek medical advice if you develop a rash, swelling, or breathing difficulty-possible allergic reaction.
Drug Interactions
| Drug/Class | Risk | Action |
|---|---|---|
| Azathioprine | Increased toxicity | Monitor blood counts |
| Antacids (high dose) | Reduced absorption | Separate dosing by ≥2 h |
| Warfarin | Potential ↑ INR | Check coagulation regularly |
Potential Side Effects
Common Side Effects
- Nausea
- Headache
- Abdominal cramps
Less Common Side Effects
- Flatulence
- Diarrhoea
- Mild skin rash
Serious Side Effects
- Persistent bloody stools
- Severe kidney impairment (elevated creatinine)
- Anaphylactic reactions (swelling, difficulty breathing) - seek urgent medical care
Who Should Avoid This Medication?
- Patients with known hypersensitivity to mesalamine or any component of the tablet
- Individuals with a history of severe Allergic Reactions to 5-ASA drugs
- Patients with acute intestinal obstruction (contraindicated)
Storage Instructions
- Keep tablets in the original container, tightly closed.
- Store at 20 °C ± 5 °C (room temperature), away from excess heat and moisture.
- Keep out of reach of children and pets.
Pentasa Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Asacol | Mesalamine (delayed-release) | Higher dose per tablet, different release profile |
| Salofalk | Mesalamine (controlled-release) | Similar efficacy, varies in dosing frequency |
| Generic mesalamine | Mesalamine (immediate-release) | Lower cost, requires more frequent dosing |
Frequently Asked Questions
How quickly will Pentasa start working?
Most patients notice improvement in bowel habits within 2-4 weeks of consistent use, though full remission may take longer.
Can I drink coffee or alcohol while taking Pentasa?
Moderate coffee and alcohol intake are generally permitted, but excessive consumption may worsen gastrointestinal symptoms.
What should I do if I experience no improvement after a month?
Re-evaluate with your healthcare provider; dosage adjustment or alternative therapy may be required.
Is it safe to use Pentasa together with probiotic supplements?
Yes, probiotics do not interact with mesalamine and may support gut health, but discuss any new supplement with your clinician.
Can I switch from a generic mesalamine to Pentasa without a doctor’s instruction?
Changing formulations can alter drug release patterns; always consult a healthcare professional before switching.
Does Pentasa affect blood sugar or cholesterol levels?
No direct impact has been reported, but individual responses vary; monitor as part of routine health checks.
What is the maximum daily dose allowed?
For ulcerative colitis, the maximum recommended daily dose is 4 g (400 mg) of mesalamine, which translates to ten 400 mg tablets.
Will Pentasa cure ulcerative colitis?
Pentasa controls inflammation and helps maintain remission but does not cure the underlying disease; lifelong management may be necessary.
Glossary
- 5-ASA (5-Aminosalicylic Acid): The active anti-inflammatory component in mesalamine drugs.
- Induction therapy: Initial treatment aimed at achieving remission.
- Maintenance therapy: Ongoing treatment to prevent relapse after remission.
Disclaimer
This handbook provides general information about Pentasa (Mesalamine) and is not a substitute for professional medical advice. Off-label use should be discussed with a qualified healthcare provider. Users are responsible for verifying any information with their own healthcare professional and for adhering to the rules of our online pharmacy platform.
Pentasa Properties
- Original Manufacturer: Ferring Pharmaceuticals
- Clinical use: Used for treating inflammatory bowel diseases, particularly ulcerative colitis.
- Spectrum of activity: Reduces inflammation in the colon.
- Mechanism of action: Inhibits the production of inflammatory chemicals in the colon.
- Classification: Aminosalicylate
- Recommended Dosage: 400-800 mg orally three times daily, adjusted based on the condition.
- Basic Side Effects: Diarrhea, Abdominal pain, Headache
- Moderate Side Effects: Nausea, Vomiting
- Serious Side Effects: Liver damage, Allergic reactions
Pentasa Drug Class
Pentasa Connected Conditions
How to purchase Pentasa on our Online Drugstore
To purchase Pentasa | Mesalamine on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Pentasa / Mesalamine pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Pentasa pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Finally got the UC symptoms under control, but man, the fatigue is crushing. I feel like I constantly need a twenty-minute nap after lunch. My doctor said that's normal with Mesalamine, something about the dose. Tip: If you are taking four pills a day, try splitting it 2 in the morning, 2 at night RIGHT before bed. It seems to soften the afternoon crash.
This is my first week on Pentasa 400mg. The diarrhea is better, less urgent, but the constant low-grade headache is killing me. It feels like pressure right above the eyes. I read online some people get fever spikes, thankfully not me yet. I feel really spaced out and can't concentrate at work. Does this side effect go away after the first month or should I push for a switch?
It works perfectly for my distal colitis, keeps me in remission since 2019. The huge downside is the cost here in Manila, it burns my wallet monthly. Also, the pills themselves are massive. User hack: take the dose with a thick smoothie or yogurt, it goes down way easier. Don't try to dry-swallow unless you want it stuck in your throat.
I tolerate the pill form much better than the enema, thank goodness. My biggest complaint is the severe dry mouth, especially at night. It wakes me up constantly needing water. I chew sugar-free gum all day just to keep saliva going. Been on 1600mg daily for three years. It stops the bleeding, which is the main goal, so I tolerate the dryness.
Mixed feelings. It stabilized my inflammation markers beautifully, but I developed insane joint pain, specifically in my knees and ankles. It feels like early arthritis. My GI doc insists it's the disease, not the Mesalamine, but the pain started exactly three weeks after starting this pill. I dropped coffee entirely because the caffeine seemed to worsen the joint stiffness.
I swear these pills give me temporary hair shedding. Not bald spots, but my brush looks full every morning. It happens every time I increase the dose and then stabilizes. It controls the flare almost instantly but the weird hair thing and the metallic taste in my mouth persist. It's a necessary evil to avoid hospital trips, though.
Just started this a few days ago, 400mg three times a day. The gut pain is much lower already, which is great, but I woke up this morning with the worst chills and back pain. Feels like the flu. I'm terrified it's a Mesalamine intolerance reaction. I called the nurse helpline, and they said to monitor my temperature. If it hits 38.5C, stop immediately.
Lifesaver for localized Crohn's in the terminal ileum. Been chewing these pills daily for 8 years now. Tip: always take with a solid meal, not just a snack. Taking it on an empty stomach gives me indigestion and cramping that rivals the disease symptoms themselves. Also, drink a full glass of water, minimum, with each dose to help your kidneys flush it out.