Buy Theophylline Online

Generic Theophylline Buyer and Patient Handbook in Singapore

What is Theophylline?

Theophylline is a xanthine bronchodilator used to treat chronic Asthma and certain allergic respiratory conditions. It relaxes airway smooth muscle, improving breathing in patients with persistent symptoms. The drug is approved by the Health Sciences Authority (HSA) and is available as a 400 mg oral tablet.

Who Should Use Theophylline?

• Adults with moderate-to-severe persistent asthma who need additional control beyond inhaled therapy.
• Patients experiencing exercise-induced bronchospasm.
• Individuals with certain allergic airway disorders where a bronchodilator is indicated.

How Does It Work?

Theophylline inhibits phosphodiesterase enzymes, raising intracellular cyclic AMP levels. ↑cAMP → relaxation of airway smooth muscle and reduced inflammatory mediator release. Think of it as “pressing the gas pedal” for the lungs, allowing air to flow more freely. Caution: Theophylline has a narrow therapeutic window; high levels can cause toxicity.

Why Choose Theophylline?

• Generic advantage: Identical efficacy to brand forms at a lower cost.
• Convenient oral dosing for patients who prefer tablets over inhalers for occasional use.
• Off-label uses (e.g., Apnea of Prematurity) should only be considered after professional guidance.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 400 mg tablet taken once daily for most adults (dose may be adjusted based on blood levels).

How to Take

• Swallow whole with a full glass of water.
• Can be taken with or without food; however, a consistent routine helps maintain steady blood levels.

Missed Dose

• If you remember within 12 hours, take the missed tablet.
• If more than 12 hours have passed, skip and resume the regular schedule.

Overdose

• Seek emergency care immediately.
• Symptoms may include Nausea, Vomiting, rapid heartbeat, or Seizures.

Special Populations

• Elderly: Start at a lower dose (e.g., 200 mg) and monitor blood levels.
• Renal or hepatic impairment: Dose reduction is often required.
• Pregnancy & breastfeeding: Use only if clearly needed; discuss risks with a healthcare professional.

Lifestyle & Diet

• Avoid large amounts of caffeine (coffee, tea, cola) as they can increase side-effects.
• Grapefruit juice may raise theophylline levels; limit intake.
• Alcohol can potentiate central nervous system effects-consume sparingly.

Precautions and Warnings

• Monitor blood theophylline concentrations regularly, especially after dose changes.
• Do not combine with strong CYP1A2 inhibitors (e.g., fluoroquinolones, cimetidine) without supervision.
• Use cautiously in patients with cardiac arrhythmias, seizures, or a history of liver disease.

Drug Interactions

Potential Side Effects

Common Side Effects

• Nausea
• Headache
• Insomnia

Less Common Side Effects

• Tremor
• Palpitations
• Diarrhea

Serious Side Effects

• Seizures
• Severe arrhythmias
• Persistent vomiting (call emergency services)

Who Should Avoid This Medication?

• Known hypersensitivity to theophylline or other xanthines.
• Uncontrolled cardiac arrhythmias.
• Active Peptic Ulcer Disease (risk of irritation).

Storage Instructions

• Keep tablets in a dry place at room temperature (15-30 °C).
• Store away from direct sunlight and moisture.
• Keep out of reach of children.

Theophylline Alternatives

Frequently Asked Questions

How quickly does Theophylline start working?

Effects may appear within 30 minutes to 2 hours, but full steady-state benefit usually requires several days of consistent dosing.

Can I take Theophylline with my inhaled corticosteroid?

Yes, the two drugs work via different mechanisms and are often prescribed together for better asthma control.

Does smoking affect Theophylline levels?

Smoking induces metabolism, potentially lowering drug concentration; dose adjustment may be needed.

Is it safe to consume caffeine while on Theophylline?

Moderate caffeine intake is generally acceptable, but high amounts can increase side-effects; limit to 1-2 cups of coffee per day.

What should I do if I experience a headache?

Stay hydrated and assess for other symptoms. If headaches are persistent or severe, consult a healthcare professional.

Can Theophylline be used for acute asthma attacks?

It is not a rescue medication; keep a fast-acting inhaler for sudden symptoms.

Why am I required to have blood tests while taking Theophylline?

Because the therapeutic range is narrow, blood monitoring ensures the dose remains effective without toxicity.

Is Theophylline suitable for children?

Pediatric use is limited and requires weight-based dosing; a specialist should determine suitability.

Glossary

• Bronchodilator: A medication that relaxes airway muscles to improve airflow.
• Cyclic AMP (cAMP): A cellular messenger that promotes muscle relaxation in the lungs.
• Therapeutic window: The blood concentration range where a drug is effective without causing harmful effects.

Disclaimer

This handbook provides general information about Theophylline and is not a substitute for professional medical advice. Off-label uses require careful consideration and should be discussed with a qualified health professional. Our service offers educational resources only; users remain responsible for their health decisions. Always consult a licensed practitioner before starting or changing any medication regimen.