Periactin

Buy Periactin
periactin

$29.70

  • Active ingredient: Cyproheptadine
  • Category: Allergy & Asthma
  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Periactin (Cyproheptadine) 4mg tablets are available to order from our Singapore pharmacy with reliable delivery. This antihistamine medication works by blocking histamine receptors to provide relief from allergy symptoms while also stimulating appetite through its effect on serotonin. It serves as an effective solution for adults and children dealing with seasonal allergies, skin reactions, or needing appetite enhancement for weight gain.

Table of contents

Periactin (Cyproheptadine) Buyer and Patient Handbook in Singapore

What is Periactin?

Periactin is a 4 mg oral antihistamine belonging to the cyproheptadine class, used to relieve allergy-related symptoms and to suppress certain Asthma triggers. It works by blocking histamine receptors and also has antiserotonergic activity, which can reduce itching, sneezing, and runny nose. Periactin is approved by the US FDA and the European EMA, and is available in Singapore as a tablet (pill).

Who Should Use Periactin?

  • Adults and adolescents (≥ 12 years) with seasonal or perennial Allergic Rhinitis.
  • Individuals experiencing mild-to-moderate allergic skin reactions (e.g., Urticaria).
  • Patients whose asthma is aggravated by allergic triggers and need adjunct symptom control.
  • Those who have not responded adequately to first-line antihistamines (under medical guidance).

How Does It Work?

Cyproheptadine, the active ingredient, binds to H1 histamine receptors, preventing histamine from triggering the classic allergy cascade (redness, swelling, mucus). It also antagonises serotonin (5-HT) receptors, which can dampen Cough reflexes and bronchial hyper-responsiveness. Think of it as a “traffic controller” that stops allergy signals from reaching the brain and lungs, reducing the urge to sneeze or wheeze.

Why Choose Periactin?

  • Proven efficacy: Decades of clinical use for allergic rhinitis and itch control.
  • Dual action: Antihistamine + antiserotonergic effects give broader symptom relief compared with standard H1 blockers.
  • Convenient dosing: Once-daily 4 mg tablet simplifies the routine.
  • Generic option: Cyproheptadine tablets are bio-equivalent and often more affordable, while Periactin offers a trusted brand formulation.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • Adults & adolescents (≥ 12 years): 4 mg (one tablet) once daily, preferably in the evening.

How to Take

  • Swallow the tablet whole with a glass of water.
  • Can be taken with or without food; a light snack may reduce mild stomach upset.

Missed Dose

  • If you remember within 12 hours, take the missed tablet.
  • If it’s been longer, skip it and resume the regular schedule-do not double-dose.

Overdose

  • Seek immediate medical attention if more than two tablets are taken at once.
  • Supportive care (e.g., monitoring breathing, gastric lavage) will be provided by clinicians.

Special Populations

  • Elderly: Start with the standard dose; monitor for Sedation.
  • Children < 12 years: Not recommended without professional advice.
  • Liver or kidney impairment: Dose adjustment may be needed; consult a healthcare professional.

Lifestyle & Diet

  • Avoid driving or operating machinery until you know how Periactin affects you (possible Drowsiness).
  • Grapefruit juice can increase blood levels of cyproheptadine; limit intake.
  • Alcohol may enhance sedation-drink cautiously.

Precautions and Warnings

  • Do not use if you have a known hypersensitivity to cyproheptadine or any tablet excipients.
  • Caution in patients with Glaucoma, urinary retention, or severe asthma.
  • May cause weight gain with long-term use; monitor body weight regularly.
  • If you experience persistent dizziness, rapid heartbeat, or severe skin reactions, stop the medication and seek medical advice.

Drug Interactions

Drug Class Risk Action
MAO inhibitors Severe hypertension, serotonin syndrome Avoid concurrent use
CNS depressants (e.g., benzodiazepines) Enhanced sedation Reduce dose or monitor closely
Anticholinergics Increased dry mouth, constipation Observe and adjust as needed

Potential Side Effects

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Increased appetite

Less Common Side Effects

  • Dizziness
  • Constipation
  • Weight gain

Serious Side Effects

  • Severe rash or hives (possible allergic reaction) - stop and seek care
  • Rapid heartbeat or palpitations - consult a doctor
  • Difficulty breathing or swelling of face/throat - call emergency services

Who Should Avoid This Medication?

  • Anyone with a documented allergy to cyproheptadine or its inactive ingredients.
  • Patients with severe hepatic impairment (risk of accumulation).
  • Individuals taking monoamine oxidase inhibitors within the past 14 days.

Storage Instructions

  • Keep the tablets in a dry place at room temperature (15 °C-30 °C).
  • Protect from direct sunlight and moisture.
  • Keep out of reach of children.

Periactin Alternatives

Name Class Key Difference
Cetirizine Second-gen antihistamine Less sedation, no antiserotonergic effect
Fexofenadine Second-gen antihistamine Non-sedating, shorter half-life
Diphenhydramine First-gen antihistamine More sedating, shorter duration

Frequently Asked Questions

How long does it take for Periactin to start working?

Most people notice relief of itching and sneezing within 30 minutes to 1 hour after the first dose. Full effect may be reached after a few days of consistent use.

Can I take Periactin with my daily multivitamin?

Yes, there are no known interactions with standard multivitamins.

Is it safe to use Periactin while pregnant or breastfeeding?

Safety during pregnancy and lactation has not been firmly established; discuss alternatives with a healthcare professional.

Will Periactin make me gain weight?

Long-term use can increase appetite, which may lead to modest weight gain in some individuals. Monitor your diet and activity level.

Can I drink coffee while on Periactin?

Caffeine does not interact significantly, but both can cause nervousness in sensitive people; use moderation.

What should I do if I feel unusually sleepy at work?

If drowsiness interferes with daily tasks, consider taking the tablet in the evening or discuss a dose adjustment with your clinician.

Does Periactin help with asthma attacks?

It can reduce allergy-triggered bronchial irritation but is not a rescue medication for acute asthma attacks; keep your prescribed reliever inhaler handy.

I missed a dose for two days; can I restart the treatment?

Yes, simply resume the regular once-daily schedule; do not take a double dose to “catch up”.

Are there any foods I should avoid while taking Periactin?

Besides grapefruit juice (which may raise drug levels), no major dietary restrictions exist.

How long can I stay on Periactin?

Short-term use (a few weeks) is common for seasonal Allergies. For chronic conditions, periodic review by a healthcare professional is advisable.

Glossary

  • Antihistamine: A drug that blocks histamine receptors, reducing allergic symptoms.
  • Antiserotonergic: Refers to inhibition of serotonin receptors, which can lessen cough and bronchial hyper-responsiveness.
  • Cyproheptadine: The generic name of the active ingredient in Periactin.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses are not discussed; any decision to start, stop, or change treatment should be made in consultation with a qualified healthcare provider. Our online platform offers convenient access to licensed pharmacies in Singapore, but the ultimate responsibility for medication safety rests with the user. Always read the product label and seek medical attention if you experience unexpected symptoms.

Periactin Properties

  • Original Manufacturer: Various
  • Clinical use: Used for the treatment of allergic disorders, migraines, and appetite stimulation.
  • Spectrum of activity: Antihistamine and antiserotonin
  • Mechanism of action: Blocks histamine H1 and serotonin 5-HT2 receptors.
  • Classification: Antihistamine
  • Recommended Dosage: 4-8 mg two to three times daily, taken orally.
  • Basic Side Effects: Drowsiness, Dry mouth
  • Moderate Side Effects: Constipation, Weight gain
  • Serious Side Effects: Rare cases of severe allergic reactions

Periactin Drug Class

Antihistamines

How to order Periactin from our Pharmacy

To order Periactin | Cyproheptadine on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Periactin / Cyproheptadine pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Periactin pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.72/166
Periactin

First week on Periactin 4mg for severe chronic hives (urticaria). The itch finally stopped, which is a massive relief. The trade-off? I feel like I constantly took a sleeping pill. My eyes are heavy all the time, I can barely focus past 10 AM. Been splitting the 4mg pill in half, taking 2mg at noon, and 2mg right before bed. Helps a little, but the daytime sedation is brutal.

Sara K. Kuala Lumpur, Malaysia

I was prescribed Periactin not for allergies, but to stimulate appetite. I lost too much weight after an illness. This stuff works almost too well. Within two days, I was constantly hungry, specifically craving carbs and sweets. Gained 3kg in two weeks. Be extremely careful if you take this long-term and struggle with weight management. My "hack" is to drink a huge glass of water right when the hunger hits to curb the immediate urge.

Ahmad R. Jakarta, Indonesia

Been using this 4mg for about a year as a preventative for migraines. It cut the frequency down from 4-5 per month to maybe 1 or 2 mild ones. It's a keeper for that reason. HOWEVER, the brain fog is real. I cannot take it in the morning. I take the entire 4mg dose at 7 PM sharp. If I take it later, I wake up still groggy. If you rely on sharp mental focus for work, stick to an evening-only routine.

Michelle C. Singapore

Just started 4mg two days ago. I was warned about the sleepiness, but wow. I feel absolutely dried out. My mouth is like sandpaper, and I keep getting weird little sharp twinges in my bladder area-like my whole system is seizing up from dehydration. I noticed that if I take the pill with a fatty food, like a bit of yogurt or a tablespoon of peanut butter, the initial rush of drowsiness isn't quite as bad. Still, the dry mouth must be managed constantly.

Nawaporn S. Bangkok, Thailand

This is my second round of Periactin, used off-label for helping with SSRI withdrawal insomnia. It guarantees 8+ hours of sleep, even if it's not the most restful sleep. The worst side effect, for me, is the severe constipation it causes. It's worse than codeine. If you use this regularly, you HAVE to supplement with fibre (psyllium husk) or stool softeners, otherwise, you'll be miserable and bloated the whole time. Don't skip that step, seriously.

Benny L. Surabaya, Indonesia

I use this for cold and exercise urticaria. It truly keeps the red welts away, even if I go swimming in a cold pool. The major issue? Mood swings. I feel slightly flat and irritable, especially if I skip a dose. I worked with my pharmacist and started taking 2mg in the morning (just enough to cover the work day) and the remaining 2mg at dinner. This leveled out the mood issues and the evening "crash" feeling.

Maria A. Cebu City, Philippines

Okay, I take the 4mg pill about three times a week for a specific skin issue. It works like a charm for inflammation. But here is the critical part: DO NOT drink coffee within 4 hours of taking this. The combination of the heavy sedative effect and the caffeine wired me up but also left me incredibly nauseous and dizzy. The few times I tried it, I felt completely physically uncoordinated for hours. Stick to plain water or herbal tea.

Huda M. Johor Bahru, Malaysia

Long-timer here, maybe three years. It completely manages my seasonal allergies (pollen, dust, etc.)-better than Zyrtec ever did. I’ve learned my body builds tolerance to the sleepiness after about two weeks, thankfully. The persistent side effect is minor short-term memory loss. I sometimes forget what I was doing right after I walk into a room. My partner handles the appointment scheduling now. Great for allergies, poor for memory.

Elias P. Geylang, Singapore

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